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Proteoglycans

Data up to Jan 2025

Published1991
Citations99
References116

Total Citations Per Year

Abstract

References (116)

Negative regulation of transforming growth factor-β by the proteoglycan decorin

1990 • 1,490 citations

Recent developments in the cell biology of basic fibroblast growth factor.

1989 • 1,049 citations

Molecular architecture of basement membranes

1990 • 937 citations

Specific inhibition of type I and type II collagen fibrillogenesis by the small proteoglycan of tendon

1984 • 865 citations

Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

1988 • 845 citations

Deduced protein sequence of bone small proteoglycan I (biglycan) shows homology with proteoglycan II (decorin) and several nonconnective tissue proteins in a variety of species

1989 • 706 citations

Cultured endothelial cells produce heparinlike inhibitor of smooth muscle cell growth

1981 • 685 citations

Proteoglycan-fibrillar collagen interactions

1988 • 677 citations

Expression and localization of the two small proteoglycans biglycan and decorin in developing human skeletal and non-skeletal tissues.

1990 • 657 citations

Multiple domains of the large fibroblast proteoglycan, versican.

1989 • 646 citations

Structure and biology of cartilage and bone matrix noncollagenous macromolecules

1989 • 565 citations

Primary structure of an extracellular matrix proteoglycan core protein deduced from cloned cDNA.

1986 • 533 citations

Molecular cloning of syndecan, an integral membrane proteoglycan.

1989 • 505 citations

Heparin : chemical and biological properties, clinical applications

1989 • 497 citations

Evidence for a 3-O-sulfated D-glucosamine residue in the antithrombin-binding sequence of heparin.

1980 • 489 citations

Aggregation of Cartilage Proteoglycans

1974 • 486 citations

Purification and partial characterization of small proteoglycans I and II, bone sialoproteins I and II, and osteonectin from the mineral compartment of developing human bone.

1987 • 437 citations

Cell biology of arterial proteoglycans.

1989 • 409 citations

Aggregation of Cartilage Proteoglycans

1974 • 393 citations

Structure and Metabolism of Connective Tissue Proteoglycans

1980 • 381 citations

Complete primary structure of the rat cartilage proteoglycan core protein deduced from cDNA clones.

1987 • 367 citations

Interaction of a 59-kDa Connective Tissue Matrix Protein with Collagen I and Collagen II

1989 • 333 citations

FSH stimulates hyaluronic acid synthesis by oocyte–cumulus cell complexes from mouse preovulatory follicles

1979 • 327 citations

A collagen-binding 59-kd protein (fibromodulin) is structurally related to the small interstitial proteoglycans PG-S1 and PG-S2 (decorin).

1989 • 295 citations

Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts.

1990 • 292 citations

Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor.

1990 • 274 citations

Distribution of keratan sulfate in cartilage proteoglycans.

1977 • 268 citations

Expression of human proteoglycan in Chinese hamster ovary cells inhibits cell proliferation

1988 • 260 citations

Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man.

1988 • 257 citations

Synthesis and Accumulation of Hyaluronic Acid and Proteoglycans in the Mouse Cumulus Cell-oocyte Complex during Follicle-stimulating Hormone-induced Mucification

1989 • 243 citations

The transforming growth factor-beta receptor type III is a membrane proteoglycan. Domain structure of the receptor.

1988 • 240 citations

The core proteins of large and small interstitial proteoglycans from various connective tissues form distinct subgroups

1985 • 240 citations

Involvement of phosphatidylinositol and insulin in the coordinate regulation of proteoheparan sulfate metabolism and hepatocyte growth.

1987 • 237 citations

Cell-surface heparan sulfate. Mechanisms of proteoglycan-cell association.

1980 • 230 citations

Cell-surface heparan sulfate. Isolation and characterization of a proteoglycan from rat liver membranes.

1979 • 223 citations

Syndecan, a developmentally regulated cell surface proteoglycan that binds extracellular matrix and growth factors

1990 • 218 citations

Molecular cloning and sequence analysis of a chondroitin sulfate proteoglycan cDNA.

1985 • 202 citations

Partial Primary Structure of the 48- and 90-Kilodalton Core Proteins oF Cell Surface-Associated Heparan Sulfate Proteoglycans of Lung Fibroblasts

1989 • 191 citations

Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans.

1990 • 184 citations

Biology of Proteoglycans

1987 • 182 citations

Characterization of an activity-dependent, neuronal surface proteoglycan identified with monoclonal antibody Cat-301

1989 • 180 citations

Binding of oligosaccharides of hyaluronic acid to proteoglycans (Short Communication)

1973 • 180 citations

Proteoglycans synthesized by smooth muscle cells derived from monkey (Macaca nemestrina) aorta.

1983 • 176 citations

The Primary Structure of the Core Protein of the Small, Leucine-rich Proteoglycan (PG I) from Bovine Articular Cartilage

1989 • 172 citations

Functions of the proteoglycans.

1986 • 157 citations

Basement membrane heparan sulfate proteoglycans are concentrated in the laminae rarae and in podocytes of the rat renal glomerulus.

1985 • 154 citations

Anchorage of collagen-tailed acetylcholinesterase to the extracellular matrix is mediated by heparan sulfate proteoglycans.

1985 • 153 citations

Identification of cDNA clones encoding different domains of the basement membrane heparan sulfate proteoglycan.

1988 • 153 citations

Cartilage proteoglycans: comparison of sectioned and spread whole molecules

1980 • 150 citations

Epithelial-mesenchymal interactions regulate the stage-specific expression of a cell surface proteoglycan, syndecan, in the developing kidney

1989 • 149 citations

Cartilage proteoglycans. Assembly with hyaluronate and link protein as studied by electron microscopy

1988 • 148 citations

ROLE OF HYALURONIDASE IN FERTILIZATION

1942 • 146 citations

Phosphorylation of chondroitin sulfate in proteoglycans from the swarm rat chondrosarcoma.

1984 • 141 citations

Extended and globular protein domains in cartilage proteoglycans

1987 • 140 citations

Cartilage ultrastructure after high pressure freezing, freeze substitution, and low temperature embedding. II. Intercellular matrix ultrastructure - preservation of proteoglycans in their native state.

1984 • 138 citations

High resolution immunoelectron microscopic localization of functional domains of laminin, nidogen, and heparan sulfate proteoglycan in epithelial basement membrane of mouse cornea reveals different topological orientations.

1988 • 132 citations

Isolation and preliminary characterization of proteoglycans dissociatively extracted from human aorta.

1981 • 128 citations

Identification of the precursor protein to basement membrane heparan sulfate proteoglycans.

1985 • 124 citations

The primary structure of link protein from rat chondrosarcoma proteoglycan aggregate.

1986 • 123 citations

Identification of the keratan sulfate attachment sites on bovine fibromodulin

1990 • 120 citations

Proteoglycans in primate arteries. III. Characterization of the proteoglycans synthesized by arterial smooth muscle cells in culture.

1983 • 120 citations

Vitreous humor of chicken contains two fibrillar systems: An analysis of their structure

1988 • 118 citations

A segment of the cartilage proteoglycan core protein has lectin-like activity.

1988 • 117 citations

Control of cell division in hepatoma cells by exogenous heparan sulfate proteoglycan

1989 • 112 citations

Structure of the glycosaminoglycan domain in the type IX collagen-proteoglycan.

1987 • 108 citations

Shared and distinct structural features of interstitial proteoglycans from different bovine tissues revealed by electron microscopy

1989 • 106 citations

Chondroitin/dermatan sulfate proteoglycan in human fetal membranes. Demonstration of an antigenically similar proteoglycan in fibroblasts.

1984 • 104 citations

Immunogold quantitation of laminin, type IV collagen, and heparan sulfate proteoglycan in a variety of basement membranes.

1988 • 104 citations

Structure of the heparan sulfate-protein linkage region. Demonstration of the sequence galactosyl-galactosyl-xylose-2-phosphate.

1985 • 104 citations

Isolation of the N-terminal globular protein domains from cartilage proteoglycans. Identification of G2 domain and its lack of interaction with hyaluronate and link protein

1989 • 104 citations

Structures of N-linked and O-linked oligosaccharides on proteoglycan monomer isolated from the Swarm rat chondrosarcoma.

1982 • 102 citations

Self-assembly of a high molecular weight basement membrane heparan sulfate proteoglycan into dimers and oligomers.

1987 • 101 citations

Investigation of molecular motion of proteoglycans in cartilage by 13C magnetic resonance.

1977 • 95 citations

Heparan sulfate proteoglycans are concentrated on the sinusoidal plasmalemmal domain and in intracellular organelles of hepatocytes.

1985 • 94 citations

Occurrence in chick embryo vitreous humor of a type IX collagen proteoglycan with an extraordinarily large chondroitin sulfate chain and short alpha 1 polypeptide.

1990 • 93 citations

The NH2-terminal amino acid sequence of bovine skin proteodermatan sulfate.

1983 • 93 citations

The Keratan Sulfate-enriched Region of Bovine Cartilage Proteoglycan Consists of a Consecutively Repeated Hexapeptide Motif

1989 • 92 citations

Cartilage proteoglycan aggregates. The link protein and proteoglycan amino-terminal globular domains have similar structures.

1987 • 91 citations

Immunological characterization of a basement membrane-specific chondroitin sulfate proteoglycan.

1989 • 90 citations

Endothelial Heparan Sulfate Proteoglycan. I. Inhibitory Effects on Smooth Muscle Cell Proliferation

1990 • 89 citations

Link protein cDNA sequence reveals a tandemly repeated protein structure.

1986 • 84 citations

Complete amino acid sequence of chicken cartilage link protein deduced from cDNA clones.

1986 • 84 citations

Functional domains of rabbit thrombomodulin.

1986 • 79 citations

Domain structure of cartilage proteoglycans revealed by rotary shadowing of intact and fragmented molecules

1984 • 79 citations

Structure of oligosaccharides and the linkage region between keratan sulfate and the core protein on proteoglycans from monkey cornea.

1983 • 74 citations

Identification of a Cell Surface-binding Protein for the Core Protein of the Basement Membrane Proteoglycan

1989 • 70 citations

Maturation of the Rat Cumulus Oophorus: A Scanning Electron Microscopic Study

1979 • 68 citations

The melanoma proteoglycan: restricted expression on microspikes, a specific microdomain of the cell surface.

1986 • 66 citations

Membrane anchoring of heparan sulfate proteoglycans by phosphatidylinositol and kinetics of synthesis of peripheral and detergent-solubilized proteoglycans in Schwann cells.

1989 • 64 citations

The alkali-labile linkage between keratan sulphate and protein

1974 • 63 citations

Structure of the cumulus matrix and zona pellucida in the golden hamster: A new view of sperm interaction with oocyte-associated extracellular matrices

1988 • 62 citations

Multiple forms of heparan sulfate proteoglycans in the Engelbreth-Holm-Swarm mouse tumor. The occurrence of high density forms bearing both heparan sulfate and chondroitin sulfate side chains.

1987 • 61 citations

Immortalization of murine connective tissue-type mast cells at multiple stages of their differentiation by coculture of splenocytes with fibroblasts that produce Kirsten sarcoma virus.

1988 • 59 citations

Characterization of novel sequences containing 3-O-sulfated glucosamine in glomerular basement membrane heparan sulfate and localization of sulfated disaccharides to a peripheral domain.

1990 • 58 citations

Colloidal gold immunostaining on deplasticized ultra-thin sections.

1988 • 57 citations

Link protein interactions with hyaluronate and proteoglycans. Characterization of two distinct domains in bovine cartilage link proteins.

1987 • 57 citations

Heparan sulfate proteoglycans of human lung fibroblasts. Structural heterogeneity of the core proteins of the hydrophobic cell-associated forms.

1987 • 54 citations

Two Forms of Plasma Membrane-intercalated Heparan Sulfate Proteoglycan in Rat Ovarian Granulosa Cells

1989 • 52 citations

Nerve terminal anchorage protein 1 (TAP-1) is a chondroitin sulfate proteoglycan: biochemical and electron microscopic characterization.

1987 • 51 citations

Isolation of a cDNA that encodes the peptide core of the secretory granule proteoglycan of rat basophilic leukemia-1 cells and assessment of its homology to the human analogue.

1988 • 51 citations

Structural Organization of Proteoglycans in Cartilage

1987 • 50 citations

Identification of the glycosaminoglycan-attachment site of mouse invariant-chain proteoglycan core protein by site-directed mutagenesis.

1988 • 49 citations

Arterial chondroitin sulfate proteoglycan: localization with a monoclonal antibody.

1988 • 48 citations

Visualization of the large heparan sulfate proteoglycan from basement membrane

1988 • 48 citations

Two linkage-region fragments isolated from skeletal keratan sulphate contain a sulphated N-acetylglucosamine residue

1990 • 34 citations

Organization of the Hamster Cumulus Extracellular Matrix: A Hyaluronate‐Glycoprotein Gel which Modulates Sperm Access to the Oocyte

1990 • 33 citations

Integral Membrane Proteoglycans as Matrix Receptors: Role in Cytoskeleton and Matrix Assembly at the Epithelial Cell Surface

1987 • 30 citations

Heparan Sulfate Species and Blood Vessel Wall Function

1987 • 27 citations

Ciba Foundation Symposium 124 ‐ Functions of the Proteoglycans

2007 • 27 citations

Physical properties of chondroitin sulphate/dermatan sulphate proteoglycans from bovine aorta

1986 • 27 citations

Heparin and heparan sulfate binding sites on B‐16 melanoma cells

1988 • 22 citations

Cell-Associated Proteoglycans in Human Malignant Melanoma

1987 • 22 citations

Structure and synthesis of intracellular proteoglycan in HL-60 human leukemic promyelocytes.

1990 • 20 citations

Intracellular Proteoglycans in Cells of the Immune System

1987 • 16 citations

Molecular Biology of Cartilage Proteoglycan (Aggrecan) and Link Protein

1990 • 16 citations

The gene that encodes the peptide core of secretory granule proteoglycans of haematopoietic cells

1990 • 3 citations

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