Changes in Cell-Mediated Immunity in Atopic Eczema

Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG.

1977 • 1,205 citations

The beta adrenergic theory of the atopic abnormality in bronchial asthma

1968 • 1,102 citations

IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.

1988 • 939 citations

Staphylococcus aureus in the lesions of atopic dermatitis

1974 • 864 citations

Regulation of the immune response by prostaglandins

1980 • 772 citations

Immunologic Functions of Ia-Bearing Epidermal Langerhans Cells

1978 • 732 citations

IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants.

1988 • 713 citations

Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones.

1988 • 509 citations

BASOPHILS IN ALLERGEN-INDUCED PATCH TEST SITES IN ATOPIC DERMATITIS

1982 • 422 citations

Dermal Deposition of Eosinophil-Granule Major Basic Protein in Atopic Dermatitis

1985 • 416 citations

The presence of IgE molecules on epidermal langerhans cells in patients with atopic dermatitis

1986 • 383 citations

RAISED SERUM-IgE LEVELS AND DEFECTIVE NEUTROPHIL CHEMOTAXIS IN THREE CHILDREN WITH ECZEMA AND RECURRENT BACTERIAL INFECTIONS

1974 • 329 citations

Immunoglobulin E in Dermatoses

1969 • 298 citations

Newer Concepts of Atopic Dermatitis

1977 • 259 citations

Microbial Flora of Atopic Dermatitis

1977 • 257 citations

Complete Correction of the Wiskott-Aldrich Syndrome by Allogeneic Bone-Marrow Transplantation

1978 • 256 citations

Characterization of the mononuclear cell infiltrate in atopic dermatitis using monoclonal antibodies

1983 • 244 citations

Involvement of immunoglobulin E in the secretory processes of alveolar macrophages from asthmatic patients.

1983 • 241 citations

Elevated leukocyte cyclic AMP—phosphodiesterase in atopic disease: a possible mechanism for cyclic AMP—agonist hyporesponsiveness

1982 • 226 citations

Depression of cell-mediated immunity in atopic eczema

1975 • 196 citations

Allergic Contact Sensitivity in Atopic Dermatitis

1973 • 179 citations

IgE-dependent release of leukotriene C4 from alveolar macrophages

1982 • 178 citations

Immunological reactivity in dermatophytosis

2006 • 144 citations

Increased leukocyte histamine release with elevated cyclic AMP-phosphodiesterase activity in atopic dermatitis

1983 • 143 citations

Immunodeficiencies in Severe Atopic Dermatitis

1976 • 141 citations

Enumeration of T cell subsets in atopic dermatitis using monoclonal antibodies

1981 • 135 citations

Subpopulations of circulating B cells and regulatory T cells involved in in vitro immunoglobulin E production in atopic patients with elevted serum immunoglobulin E.

1980 • 132 citations

Functional heterogeneity among human inducer T cell clones.

1988 • 131 citations

Human T-lymphocyte subset specificity of the regulatory effects of leukotriene B4.

1984 • 131 citations

In situ quantification of T-lymphocyte subsets and Langerhans cells in the inflammatory infiltrate of atopic eczema

1985 • 128 citations

Skin Histamine Levels in Chronic Atopic Dermatitis**From the Division of Dermatology, Department of Medicine, Western Reserve University, School of Medicine, Cleveland, Ohio.(Aided by grant from Research and Development Division, Department of the Army, Contract #DA-49-007-MD-573)

1960 • 127 citations

A Clinical, Mycological, and Immunological Survey for Dermatophytosis

1973 • 124 citations

Bacterial infection and atopic eczema.

1986 • 121 citations

Human IgE Biosynthesis in Vitro: Studies with Atopic and Normal Blood Mononuclear Cells and Subpopulations

1979 • 120 citations

T Lymphocyte Numbers and Function in Human IgE-Mediated Allergy

1978 • 112 citations

SOME RESULTS OF PATCH TESTS

1937 • 109 citations

Pityrosporum orbiculare--a pathogenic factor in atopic dermatitis of the face, scalp and neck?

1985 • 105 citations

Phosphodiesterase Inhibition by Ro 20-1724 Reduces Hyper-IgE Synthesis by Atopic Dermatitis Cells In Vitro

1985 • 104 citations

Essential Fatty Acids in Serum Lecithin of Children with Atopic Dermatitis and in Umbilical Cord Serum of Infants with High or Low IgE Levels

1987 • 98 citations

T Lymphocytes in Atopic Children

1976 • 94 citations

Clinical and Immunologic Aspects of the Hyperimmunoglobulin E Syndrome

1988 • 93 citations

Circulating IgG autoantibodies to IgE in atopic syndromes

1986 • 91 citations

Immunological Capabilities of Patients with Atopic Dermatitis*

1966 • 91 citations

Eczema Vaccinatum

1964 • 90 citations

The presence of IgE on macrophages and dendritic cells infiltrating into the skin lesion of atopic dermatitis

1987 • 89 citations

Recurrent viral infections in patients with past or present atopic dermatitis

1986 • 87 citations

Localization and content of histamine in normal and diseased skin.

1967 • 80 citations

LYMPHOCYTE TRANSFORMATION INDUCED BY AUTOLOGOUS CELLS

1973 • 79 citations

Leukocyte and Lymphocyte Cyclic AMP Responses In Atopic Eczema

1977 • 73 citations

The probable role of interferon in allergy.

1975 • 71 citations

COMPLEXED IgE IN ATOPY

1977 • 71 citations

Human IgE synthesis in vitro: a reassessment.

1981 • 70 citations

NUMERICAL AND FUNCTIONAL DEFICIENCY OF SUPPRESSOR T CELLS PRECEDES DEVELOPMENT OF ATOPIC ECZEMA

1983 • 69 citations

Defective T cell function in atopic dermatitis

1976 • 68 citations

Nonspecific suppressor cell function in atopic subjects

1979 • 67 citations

Differences between normal and milk allergic subjects in their immune responses after milk ingestion.

1983 • 67 citations

The human autologous mixed lymphocyte reaction. III. Immune circuits.

1982 • 66 citations

Quantitative analysis of T-lymphocyte subsets in atopic eczema, using monoclonal antibodies and flow cytoafluorimetry

1983 • 65 citations

Elevated umbilical cord blood leukocyte cyclic adenosine monophosphate-phosphodiesterase activity in children with atopic parents

1984 • 64 citations

T Cell Abnormalities in Atopic Dermatitis Patients: Imbalances in T Cell Subpopulations and Impaired Generation of Con A-induced Suppressor Cells

1981 • 62 citations

Histamine inhibits interferon-γ production via suppression of interleukin 2 synthesis

1986 • 59 citations

Abnormalities of leukotaxis in atopic dermatitis

1977 • 58 citations

Histamine Inhibits Interleukin 1 Production by Lipopolysaccharide‐Stimulated Human Peripheral Blood Monocytes

1988 • 58 citations

Histamine suppression of lymphocyte activation.

1980 • 56 citations

Altered arachidonic acid content in polymorphonuclear and mononuclear cells from patients with allergic rhinitis and/or asthma

1986 • 55 citations

Quantitative and functional deficit of suppressor T cells in children with atopic eczema.

1982 • 54 citations

Modulation of Natural Killer Cell Activity in Patients with Atopic Dermatitis

1984 • 53 citations

IgE immune complexes stimulate arachidonic acid release by mouse peritoneal macrophages.

1982 • 53 citations

Selective deficiency of a T cell subpopulation in active atopic dermatitis.

1980 • 52 citations

Increased Sensitivity of Lymphocytes from Atopic Individuals to Histamine‐Induced Suppression

1977 • 52 citations

Cell-mediated immunity in cutaneous disease

1986 • 51 citations

Interferon and natural killer cells in systemic lupus erythematosus.

1982 • 49 citations

Histamine modulates the production of interferon-γ and interleukin-2 by mitogen-activated human mononuclear blood cells

1985 • 48 citations

Plasma complement and histamine changes in atopic dermatitis*

1979 • 47 citations

RECURRENT ECZEMA HERPETICUM ASSOCIATED WITH ICHTHYOSIS VULGARIS

1972 • 46 citations

Epstein-Barr Virus Antibodies in Children with Atopic Disease

1981 • 46 citations

T lymphocytes and blood eosinophils in early infancy in relation to heredity for allergy and type of feeding

1979 • 45 citations

Increased Serum Levels of Antibodies to Epstein-Barr Virus in Adults with History of Atopic Dermatitis

1984 • 42 citations

Staphylococcal colonization, infection, and atopic dermatitis—Association not etiology

1986 • 42 citations

Abnormal Suppressor Cell Function in Atopic Dermatitis

1981 • 42 citations

Epidermal cytokines: properties of epidermal cell thymocyte-activating factor (ETAF).

1984 • 42 citations

PPD and mitogen responsiveness of lymphocytes from patients with atopic dermatitis.

1977 • 41 citations

Cellular basis of defective cell-mediated lympholysis in atopic dermatitis.

1983 • 41 citations

Defective monocyte and polymorphonuclear leukocyte chemotaxis in atopic disease

1978 • 40 citations

ELECTRARGOL IN SMALL-POX

1913 • 39 citations

Cell-mediated cytotoxicity against skin fibroblasts in atopic dermatitis.

1982 • 37 citations

An in vitro study of depressed cell-mediated immunity and of T and B lymphocytes in atopic dermatitis

1977 • 35 citations

Lymphocyte Response to Phytohemagglutinin in Atopic Dermatitis

1979 • 34 citations

Histamine and immune modulation.

1983 • 33 citations

Immunoregulation in Atopic Dermatitis: Functional Analysis of T-B Cell Interactions and the Enumeration of Fc Receptor-Bearing T Cells

1983 • 33 citations

A role for IgE in patch test reactions to inhalant allergens in patients with atopic dermatitis

1988 • 31 citations

Depression of Neutrophil Chemotaxis in Atopic Individuals

1981 • 29 citations

Suppressive effect of IgE soluble immune complex on neutrophil chemotaxis.

1983 • 28 citations

Decreased natural killer cell activity in atopic eczema.

1985 • 26 citations

Neutrophil Chemotaxis in Patients With Atopic Dermatitis Without Infection

1978 • 24 citations

Natural Cell-Mediated Cytotoxic Activity in the Peripheral Blood of Patients With Atopic Dermatitis

1982 • 24 citations

Impairment of the autologous mixed lymphocyte reaction in atopic dermatitis.

1983 • 22 citations

Impaired Monocyte Cyclic AMP Responses and Monocyte Cytotoxicity in Atopic Dermatitis

1980 • 21 citations

Production of interferon and lymphoproliferative response in whole blood cultures derived from patients with atopic dermatitis

1987 • 21 citations

Langerhans Cell—and T-Lymphocyte Functions in Patients With Atopic Dermatitis With Disseminated Cutaneous Herpes Simplex Virus Infection

1987 • 21 citations

Infections as contributing factors to atopic dermatitis

1989 • 20 citations

Studies on T-cell subsets in atopic dermatitis: Human T-cell subpopulations defined by specific monoclonal antibodies

1982 • 20 citations

FcIgG Receptor-Bearing Lymphocytes and Monoclonal Antibody-Defined T Cell Subsets in Atopic Dermatitis: Effect of Treatment with Thymopoietin Pentapeptide (TP-5)

1982 • 20 citations

Interferon production in primary immunodeficiencies

1984 • 20 citations

Delayed dermal and epidermal reactivity in atopic dermatitis (prurigo Besnier). 3. Further studies with bacterial and viral allergens.

1968 • 18 citations

Atopic Dermatitis and Tuberculin Reactivity

1977 • 17 citations

Antibody‐Dependent Monocyte‐Mediated Cytotoxidty in Severe Atopic Dermatitis

1979 • 17 citations

Elevated IgG immune complexes in children with atopic eczema

1984 • 15 citations

Besnier's prurigo (atopic dermatitis) in children.

1966 • 15 citations

Study of T-cell subpopulations defined by monoclonal antibodies in asthmatic children with or without atopic eczema and normals.

1982 • 15 citations

Lymphocyte Stimulation with Phorbol Myristate Acetate in Atopic and Non-Atopic Individuals

1979 • 14 citations

Effect of Cyclic AMP-Elevating Agents on Human Spontaneous IgE Synthesis in vitro

1984 • 13 citations

T-cell subsets in patients with mild and severe atopic dermatitis.

1985 • 13 citations

ADCC effector function in patients with atopic dermatitis

1980 • 13 citations

Atopic dermatitis

1988 • 13 citations

Characterization of T cell subsets in patients with atopic dermatitis using OKT monoclonal antibodies.

1985 • 13 citations

Stimulatory and Inhibitory Effects of Cyclic AMP on Lymphocytes from Atopic Children

1979 • 12 citations

Activation of T lymphocytes and autologous mixed lymphocyte reaction in allergic patients.

1984 • 12 citations

Abnormal regulation of in vitro IgE synthesis by T cells obtained from patients with atopic dermatitis

1985 • 12 citations

Monocyte Chemotaxis under Agarose: Defects in Atopic Disease, Aspirin Therapy, and Mucocutaneous Candidiasis

1980 • 12 citations

Severe varicella in a child with atopic eczema and ichthyosis.

1986 • 11 citations

T-Cell Subset Assay

1988 • 8 citations

Evidence for histamine-mediated inhibition of monocyte chemotaxis in atopic dermatitis

1982 • 8 citations

Adherent Suppressor Cells in Atopic Disease

1981 • 7 citations

Lymphocyte Transformation Induced by Autologous Cells

1985 • 6 citations

Role of T gamma and T mu sub-set lymphocytes in allergic disease.

1980 • 5 citations

Atopic Dermatitis, Eczema Herpeticum, Infectious Mononucleosis, and Depressed Cell-Mediated Immunity

1978 • 4 citations

Viability of Cultured Peripheral Blood Mononuclear Cells from Atopic Individuals

1984 • 3 citations

LYMPHOCYTE TRANSFORMATION

1974 • 1 citations

Suppressor cell phenotype deficiency and its restoration by thymopoietin pentapeptide in atopic dermatitis.

1983 • 1 citations

Deleted Work

1955 • 0 citations