Expression and function of membrane attack complex inhibitory proteins on thyroid follicular cells.

CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.

1989 • 640 citations

Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers.

1990 • 529 citations

Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria.

1989 • 407 citations

The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9.

1990 • 403 citations

Autoimmune Thyroid Disease: Developments in Our Understanding

1984 • 344 citations

Interferon-gamma induces HLA-DR expression by thyroid epithelium.

1985 • 314 citations

Homologous species restriction in lysis of human erythrocytes: a membrane-derived protein with C8-binding capacity functions as an inhibitor.

1986 • 241 citations

Isolation of a human erythrocyte membrane protein capable of inhibiting expression of homologous complement transmembrane channels.

1986 • 240 citations

A novel membrane glycoprotein capable of inhibiting membrane attack by homologous complement

1989 • 203 citations

Hypothyroidism as a Late Sequela in Patients with Graves' Disease Treated with Antithyroid Agents

1979 • 172 citations

Presence of the organ-specific 'microsomal' autoantigen on the surface of human thyroid cells in culture: its involvement in complement-mediated cytotoxicity.

1981 • 170 citations

Thein VitroRegulation of Human Thyrocyte HLA-DR Antigen Expression*

1985 • 121 citations

Tissue distribution of HRF20, a novel factor preventing the membrane attack of homologous complement, and its predominant expression on endothelial cells in vivo.

1990 • 101 citations

Regulatory control of complement on blood platelets

1989 • 101 citations

Human T cells from autoimmune and normal individuals can produce tumor necrosis factor

1987 • 94 citations

The thyroid "microsomal" antibody revisited. Its paradoxical binding in vivo to the apical surface of the follicular epithelium.

1984 • 77 citations

Immune complex deposits in Graves' disease and Hashimoto's thyroiditis

1977 • 74 citations

Functional analysis of intercellular adhesion molecule‐1‐expressing human thyroid cells

1990 • 67 citations

Isolation and characterization of a membrane-attack-complex-inhibiting protein present in human serum and other biological fluids

1990 • 65 citations

Immunoaffinity purification of human complement component C9 using monoclonal antibodies

1983 • 58 citations

Terminal complement complexes and C1/C1 inhibitor complexes in autoimmune thyroid disease.

1989 • 47 citations

Immunohistochemical analysis of intrathyroidal lymphocytes in Graves' disease: Evidence of activated T cells and production of interferon-γ

1988 • 46 citations

Expression of HRF20, a regulatory molecule of complement activation, on peripheral blood mononuclear cells.

1990 • 42 citations

Demonstration of Interleukin-βon Perifollicular Endothelial Cells in the Thyroid Glands of Patients with Graves’ Disease*

1989 • 24 citations

Protection of human amniotic epithelial cells (HAEC) from complement-mediated lysis: expression on the cells of three complement inhibitory membrane proteins.

1990 • 23 citations

The Homologous Species Restriction of the Complement Attack: Structure and Function of the C8 Binding Protein

1988 • 20 citations

Asialoagalactothyroglobulin binds to the surface of human thyroid cells at a site distinct from the 'microsomal' autoantigen.

1984 • 16 citations

Thyroid follicular cell function after non-lethal complement membrane attack

1990 • 12 citations