Control of synthesis and release of radioactive acetylcholine in brain slices from the rat. Effects of neurotropic drugs

The mechanism of excitation by acetylcholine in the cerebral cortex

1971 • 698 citations

Tetrodotoxin‐resistant electric activity in presynaptic terminals

1969 • 613 citations

The measurement of synaptic delay, and the time course of acetylcholine release at the neuromuscular junction

1965 • 600 citations

Electrochemical aspects of physiological and pharmacological action in excitable cells. I. The resting cell and its alteration by extrinsic factors.

1958 • 579 citations

Further study of the role of calcium in synaptic transmission

1970 • 461 citations

Effect of barbiturates on ‘quantal’ synaptic transmission in spinal motoneurones

1969 • 429 citations

MICRODETERMINATION OF CHOLINE ACETYLASE IN NERVOUS TISSUE

1965 • 367 citations

Spontaneous and evoked activity of motor nerve endings in calcium Ringer

1969 • 352 citations

Changes in end‐plate activity produced by pre‐synaptic polarization

1954 • 286 citations

The mechanism of acetylcholine release from parasympathetic nerves

1971 • 251 citations

Tetrodotoxin and neuromuscular transmission

1967 • 249 citations

Electrochemical aspects of physiological and pharmacological action in excitable cells. II. The action potential and excitation.

1958 • 240 citations

The control by internal calcium of membrane permeability to sodium and potassium

1971 • 232 citations

Calcium and synaptic transmission in a sympathetic ganglion

1940 • 194 citations

Choline Acetyltransferase from Rat Brain

1968 • 188 citations

Quantal Mechanism of Neural Transmitter Release

1971 • 188 citations

Ionic Requirements of Synaptic Transmitter Release

1967 • 169 citations

Choline ester formation in, and choline esterase activities of, tissues in vitro

1936 • 166 citations

[¹⁴C]ACETYLCHOLINE SYNTHESIS BY CORTEX SLICES OF RAT BRAIN¹²

1968 • 158 citations

Acetylcholine metabolism in the central nervous system

1939 • 152 citations

STANDARDIZATION OF A RADIOCHEMICAL ASSAY OF CHOLINE ACETYLTRANSFERASE AND A STUDY OF THE ACTIVATION OF THE ENZYME IN RABBIT BRAIN

1971 • 149 citations

Actions of dinitrophenol and some other metabolic inhibitors on cortical neurones

1971 • 138 citations

The inhibition of chymotrypsin by diethyl p-nitrophenyl phosphate

1952 • 136 citations

On the mechanism of acetylcholine formation in brain in vitro

1938 • 136 citations

Acetylcholine release in the cat's superior cervical ganglion

1953 • 134 citations

Some esterases of the rat

1954 • 123 citations

Barbiturates and oxidative phosphorylation

1960 • 114 citations

Calcium: Is It Required for Transmitter Secretion?

1971 • 109 citations

Competition between sodium and calcium ions in transmitter release at mammalian neuromuscular junction

1966 • 107 citations

THE ROLE OF SODIUM IONS IN THE METABOLISM OF ACETYLCHOLINE

1963 • 106 citations

CONTROL OF ACETYLCHOLINE SYNTHESIS?THE INHIBITION OF CHOLINE ACETYLTRANSFERASE BY ACETYLCHOLINE

1969 • 104 citations

The action of acetylcholine on conduction in mammalian non‐myelinated fibres and its prevention by anticholinesterase

1960 • 101 citations

Exchangeability of radioactive acetylcholine with the bound acetylcholine of synaptosomes and synaptic vesicles

1968 • 101 citations

Excitatory acidic amino acids and the cation content and sodium ion flux of isolated tissues from the brain

1968 • 96 citations

SPECIES DIFFERENCES IN SUBCELLULAR DISTRIBUTION OF CHOLINE ACETYLASE IN THE CNS

1965 • 92 citations

The influence of atropine on the release and uptake of acetylcholine by the isolated cerebral cortex of the rat

1966 • 92 citations

IONIC BASIS FOR THE DEPOLARIZATION OF CEREBRAL TISSUES BY EXCITATORY ACIDIC AMINO ACIDS

1966 • 89 citations

Carbohydrate – Amino-Acid Inter-Relations in Brain Cortex In Vitro

1959 • 85 citations

Cholinergic receptors at sympathetic preganglionic nerve terminals

1968 • 78 citations

Water uptake and energy metabolism in brain slices from the rat

1970 • 70 citations

Effects of acetylcholine on axonal conduction of lobster nerve

1963 • 64 citations

The effect of sodium ions on neuromuscular transmission

1952 • 63 citations

Antagonism between Na+ and Ca2+ at the Neuromuscular Junction

1965 • 63 citations

Molecular transport at cell membranes

1965 • 62 citations

The subcellular distribution of [N-Me−3H]-acetylcholine synthesized by brain in vivo

1969 • 61 citations

ON THE ORIGIN OF THE ACETYL MOIETY OF ACETYLCHOLINE IN BRAIN STUDIED WITH A DIFFERENTIAL LABELLING TECHNIQUE USING ³H‐¹⁴C‐MIXED LABELLED GLUCOSE AND ACETATE

1970 • 59 citations

Effect of Calcium Ions on the Release of Acetylcholine from the Cerebral Cortex

1967 • 58 citations

A COMPARISON OF THE N‐ALKYL GROUP SPECIFICITY OF CHOLINE ACETYLTRANSFERASE FROM DIFFERENT SPECIES.*

1964 • 56 citations

Biological Sciences: Release of Protein from Mouse Motor Nerve Terminals

1972 • 55 citations

Properties and biological significance of choline acetylase.

1957 • 55 citations

Tetrodotoxin-sensitive uptake of ions and water by slices of rat brain in vitro

1970 • 53 citations

A specific antidote against lethal alkyl phosphate intoxication. IV. Effects in brain

1957 • 50 citations

Action of Snake Venom on Acetylcholine Synthesis in Brain

1952 • 47 citations

THE SYNTHESIS AND STORAGE OF ACETYLCHOLINE IN THE STRIATUM *

1966 • 45 citations

Presynaptic Action of Central Depressant Drugs: Inhibition of Depolarization–Secretion Coupling

1972 • 44 citations

Effect of ouabain on ion transport and metabolic turnover of phospholipid of brain slices

1961 • 44 citations

Metabolism of rat brain mitochondria. Studies on the potassium ion-stimulated oxidation of pyruvate

1971 • 44 citations

Uptake of acetylcholine in rat brain cortex slices

1969 • 41 citations

Vesicular and Synaptoplasmic Synthesis of Acetylcholine

1970 • 40 citations

Cholinergic Neurons in Vertebrates

1961 • 38 citations

ORIGIN AND FUNCTION OF SYNAPTIC VESICLES

1971 • 38 citations

Effects of inhibitors of glutamine synthesis on the inhibition of acetylcholine synthesis in brain slices by ammonium ions

1953 • 38 citations

Acetylcholine metabolism in the central nervous system

1939 • 38 citations

The release of acetylcholine by acetylcholine in the cat's superior cervical ganglion

1970 • 37 citations

Human Placental Choline Acetyltransferase

1971 • 35 citations

FACTORS AFFECTING THE SYNTHESIS OF ACETYLCHOLINE BY BRAIN SLICES

1950 • 35 citations

Neuromuscular Pharmacology

1965 • 33 citations

Studies on ali-esterases. 4. Differentiation of esterases in pancreas and brain by the use of organophosphorus inhibitors

1956 • 32 citations

Relation between Na+-K+ transport and the uptake of choline by brain slices

1967 • 27 citations

FURTHER STUDIES ON THE POTASSIUM AND SODIUM CONCENTRATIONS OF MAMMALIAN CEREBRAL SLICES IN VITRO

1964 • 26 citations

THE EFFECT OF SOME INORGANIC IONS ON BRAIN SLICES METABOLIZING GLUCOSE OR PYRUVATE

1957 • 26 citations

Effects of tetrodotoxin and anaesthetics on brain metabolism and transport during anoxia

1972 • 26 citations

Effect of Lithium Ions on the Release of Acetylcholine from the Cerebral Cortex

1971 • 22 citations

THE ABSENCE OF 'SURPLUS' ACETYLCHOLINE FORMATION IN PRISMS PREPARED FROM RAT CEREBRAL CORTEX

1972 • 21 citations

Applied electrical pulses and the ammonia and acetylcholine of isolated cerebral cortex slices

1954 • 20 citations

FACTORS CONTROLLING THE LIBERATION OF ACETYLCHOLINE AT THE NEUROMUSCULAR JUNCTION

1959 • 16 citations

The effect of calcium on the sodium permeability of a giant nerve fibre.

1955 • 15 citations

Inhibition of cholinesterases of rat diaphragm muscle by organophosphates and spontaneous recovery of enzyme activity in vitro

1972 • 14 citations

Effect of triperidol on processes involving acetylcholine in rat brain in vitro

1971 • 14 citations

Effects of anesthetics on sodium uptake into rat brain cortex in vitro

1972 • 13 citations

STUDIES ON SOLUBLE PROTEINS RELEASED FROM THE SYNAPTIC VESICLES OF RAT BRAIN CORTEX

1971 • 12 citations

Oxidation of succinate and pyruvate in rat brain and its effect on barbiturate anaesthesia

1969 • 9 citations