Subnuclear fractionation by mild micrococcal-nuclease treatment of nuclei of different transcriptional activities causes a partition of expressed and non-expressed genes

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

Isolation of High‐Molecular‐Weight DNA from Mammalian Cells

1973 • 1,723 citations

Nuclei from Rat Liver: Isolation Method That Combines Purity with High Yield

1966 • 1,687 citations

Structure of Chromatin

1977 • 1,276 citations

[29] Analysis of repeating DNA sequences by reassociation

1974 • 1,040 citations

Electron microscopic and biochemical evidence that chromatin structure is a repeating unit

1975 • 860 citations

Action of micrococcal nuclease on chromatin and the location of histone H1

1977 • 686 citations

Chromatin

1978 • 569 citations

Selective digestion of transcriptionally active ovalbumin genes from oviduct nuclei.

1976 • 523 citations

Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences.

1978 • 459 citations

The chromatin structure of specific genes: I. Evidence for higher order domains of defined DNA sequence

1979 • 445 citations

Ultrastructural patterns of RNA synthesis during early embryogenesis of Drosophila melanogaster

1976 • 409 citations

Biogenesis of mRNA: Genetic Regulation in Mammalian Cells

1973 • 398 citations

Kinetic analysis of deoxyribonuclease I cleavages in the nucleosome core: Evidence for a DNA superhelix

1978 • 383 citations

Isolation of a subclass of nuclear proteins responsible for conferring a DNase I-sensitive structure on globin chromatin.

1979 • 337 citations

Fractionation of hen oviduct chromatin into transcriptionally active and inactive regions after selective micrococcal nuclease digestion

1978 • 313 citations

Structure of chromatin containing extensively acetylated H3 and H4

1978 • 290 citations

Gel Electrophoresis of Avian Leukosis and Sarcoma Viral RNA in Formamide: Comparison with Other Viral and Cellular RNA Species

1973 • 223 citations

Comparative organization of active transcription units in Oncopeltus fasciatus

1976 • 205 citations

Changes of nucleosome frequency in nucleolar and non-nucleolar chromatin as a function of transcription: an electron microscopic study

1978 • 161 citations

Nucleosome Structure III: The Structure and Transcriptional Activity of the Chromatin Containing the Ovalbumin and Globin Genes in Chick Oviduct Nuclei

1978 • 161 citations

DNA associated with hyperacetylated histone is preferentially digested by DNase I

1978 • 147 citations

Acetylated histone H4 is preferentially associated with template-active chromatin.

1978 • 146 citations

Genes transcribed at diverse rates have a similar conformation in chromatin

1977 • 140 citations

Effect of histone acetylation on structure and in vitro transcription of chromatin

1978 • 132 citations

Activation of chromatin by acetylation of histone side chains.

1976 • 132 citations

Structure of transcriptionally active chromatin.

1975 • 127 citations

An altered subunit configuration associated with the actively transcribed DNA of integrated adenovirus genes

1977 • 124 citations

Active conformation of the globin genes in uninduced and induced mouse erythroleukemia cells

1978 • 110 citations

Partial purification of transcriptionally active nucleosomes from trout testis cells

1978 • 106 citations

DNAase I, DNAase II and staphylococcal nuclease cut at different, yet symmetrically located, sites in the nucleosome core

1978 • 102 citations

Selective degradation of integrated murine leukemia proviral DNA by deoxyribonucleases

1977 • 100 citations

Enzymatic fractionation of nuclei: Polynucleosomes and RNA polymerase II as endogenous transcriptional complexes

1978 • 97 citations

Structure of transcriptionally-active chromatin subunits

1977 • 93 citations

Cloning of a double-stranded cDNA that codes for a portion of chicken preproalbumin. A general method for isolating a specific DNA sequence from partially purified mRNA.

1978 • 90 citations

Characterisation of bacterial clones containing DNA sequences derived from Xenopus laevis vitellogenin mRNA

1979 • 81 citations

Morphology of Transcriptionally Active Chromatin

1978 • 72 citations

Sequence composition of the template-active fraction of rat liver chromatin

1976 • 65 citations

Chapter 6 Isolation and Characterization of Chromatin Subunits

1978 • 59 citations

Analysis of Xenopus laevis globins during development and erythroid cell maturation and the construction of recombinant plasmids containing sequences derived from adult globin mRNA

1979 • 52 citations

Translation of Xenopus vitellogenin mRNA during primary and secondary induction

1978 • 50 citations

H1 Histone and the Condensation of Chromatin and DNA

1978 • 50 citations

Preparation of soluble chromatin and specific chromatin fractions with restriction nucleases

1977 • 49 citations

Template-engaged and free RNA polymerases during Xenopus erythroid cell maturation

1978 • 47 citations

Chemical and physical properties of fractionated chromatin.

1975 • 47 citations

The role of H1 histone phosphorylation in the cell cycle

1978 • 46 citations

Deoxyribonuclease I produces staggered cuts in the DNA of chromatin

1977 • 46 citations

The erythroid cells of anaemic Xenopus laevis. I. studies on cellular morphology and protein and nucleic acid synthesis during differentiation

1975 • 44 citations

Differential subnuclear distribution of polyadenylate-rich ribonuclei acid during induction of egg-yolk protein synthesis in male Xenopus liver by oestradiol-17β

1975 • 38 citations

Sub-nuclear fractionation

1974 • 37 citations

Nucleosome structure

1978 • 37 citations

Nuclear protein synthesis and phosphorylation in Friend erythroleukemia cells stimulated with DMSO

1978 • 35 citations

Sub-nuclear fractionation

1974 • 33 citations

Chapter 28 Methods for Fractionation of Chromatin into Transcriptionally Active and Inactive Segments

1977 • 30 citations

Two Chromatin Fractions with Different Metabolic Properties of Non‐histone Proteins and of Newly Synthesized RNA

1979 • 26 citations

Enrichment for the globin coding region in a chromatin fraction from chick reticulocytes by endonuclease digestion

1977 • 26 citations

Chapter 3 Dissection of the Eukaryotic Chromosome with Deoxyribonucleases

1978 • 8 citations

Transcription, processing and structure of chromatin in SV40-transformed cell

1978 • 6 citations

Initiation of transcription in normal and phosphorylated rat liver nucleosomes

1978 • 5 citations