Cytoskeletal Abnormalities in Parkinson’s Disease

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1983 • 2,149 citations

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

1986 • 1,942 citations

HANDBUCH DER NEUROLOGIE

1912 • 691 citations

Permanent human parkinsonism due to 1‐methy 1–4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)

1985 • 620 citations

Diffuse type of Lewy body disease: progressive dementia with abundant cortical Lewy bodies and senile changes of varying degree--a new disease?

1984 • 397 citations

Locus ceruleus lesions and eosinophilic inclusions in MPTP‐treated monkeys

1986 • 347 citations

Slow Axonal Transport of Neurofilament Proteins: Impairment of β,β′-Iminodipropionitrile Administration

1978 • 340 citations

PHASE AND ELECTRON MICROSCOPIC OBSERVATIONS OF LEWY BODIES AND MELANIN GRANULES IN THE SUBSTANTIA NIGRA AND LOCUS CAERULEUS IN PARKINSONʼS DISEASE

1965 • 330 citations

THE DISTRIBUTION OF LEWY BODIES IN THE CENTRAL AND AUTONOMIC NERVOUS SYSTEMS IN IDIOPATHIC PARALYSIS AGITANS

1960 • 291 citations

Lewy Bodies of Parkinson's Disease Contain Neurofilament Antigens

1983 • 256 citations

Lewy bodies in cerebral cortex. Report of three cases

1978 • 230 citations

Parkinson's disease: Distribution of Lewy bodies and monoamine neuron system

1976 • 205 citations

Association of microtubule-associated protein 2 (MAP 2) with microtubules and intermediate filaments in cultured brain cells.

1983 • 193 citations

Handbuch der Neurologie.

1911 • 192 citations

Ultrastructure of Lewy bodies in the stellate ganglion

1976 • 154 citations

Pathogenesis of experimental giant neurofilamentous axonopathies: A unified hypothesis based on chemical modification of neurofilaments

1985 • 144 citations

Immunocytochemical studies of neurofilament antigens in the neurofibrillary pathology induced by aluminum

1986 • 131 citations

Reaction of Lewy bodies with antibodies to phosphorylated and non-phosphorylated neurofilaments

1986 • 131 citations

Ultrastructural observations in Parkinsonism

1969 • 103 citations

Microtubule-neurofilament segregation produced by beta, beta'- iminodipropionitrile: evidence for the association of fast axonal transport with microtubules

1983 • 92 citations

Microtubule-associated protein 2 within axons of spinal motor neurons: associations with microtubules and neurofilaments in normal and beta,beta'-iminodipropionitrile-treated axons.

1985 • 89 citations

Immunohistochemical localization of neurofilament protein in neuronal degenerations

1984 • 66 citations

Tyrosine hydroxylase protein in Lewy bodies of parkinsonian and senile brains

1984 • 52 citations

Giant axonal neuropathy

1981 • 34 citations

Promotion of Microtubule Assembly by Neurofilament‐Associated Microtubule‐Associated Proteins

1984 • 30 citations

Infantile neurodegenerative disease with neuronal accumulation of phosphorylated neurofilaments

1987 • 27 citations

monoclonal antibodies raised against Lewy bodies in brains from subjects with Parkinson's disease

1985 • 15 citations

ACCUMULATION OF PHOSPHORYLATED NEUROFILAMENTS IN THE ANTERIOR HORN MOTOR NEURONS OF ALS PATIENTS

1986 • 8 citations

Deleted Work

1955 • 0 citations