Simvastatin upregulates coronary vascular endothelial nitric oxide production in conscious dogs

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1994 • 8,631 citations

The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels

1996 • 7,450 citations

Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia

1995 • 7,378 citations

Regulation of the mevalonate pathway

1990 • 5,282 citations

PREVENTION OF CORONARY HEART DISEASE WITH PRAVASTATIN IN MEN WITH HYPERCHOLESTEROLEMIA

1995 • 3,524 citations

Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors

1998 • 1,860 citations

Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease

1994 • 1,697 citations

Post-transcriptional Regulation of Endothelial Nitric Oxide Synthase mRNA Stability by Rho GTPase

1998 • 1,034 citations

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

1998 • 978 citations

Simvastatin, an HMG–Coenzyme A Reductase Inhibitor, Improves Endothelial Function Within 1 Month

1997 • 968 citations

Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression.

1994 • 941 citations

Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions Potential for pharmacological interventions

1997 • 594 citations

Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase

1995 • 540 citations

Endothelium-dependent dilation of the coronary microvasculature is impaired in dilated cardiomyopathy.

1990 • 444 citations

Inhibition of 3-Hydroxy-3-methylglutaryl (HMG)-CoA Reductase Blocks Hypoxia-mediated Down-regulation of Endothelial Nitric Oxide Synthase

1997 • 393 citations

Short-term cholesterol lowering decreases size and severity of perfusion abnormalities by positron emission tomography after dipyridamole in patients with coronary artery disease. A potential noninvasive marker of healing coronary endothelium.

1994 • 338 citations

Simvastatin Preserves the Ischemic-Reperfused Myocardium in Normocholesterolemic Rat Hearts

1999 • 334 citations

Reduced Nitric Oxide Production and Altered Myocardial Metabolism During the Decompensation of Pacing-Induced Heart Failure in the Conscious Dog

1998 • 310 citations

Reduced Gene Expression of Vascular Endothelial NO Synthase and Cyclooxygenase-1 in Heart Failure

1996 • 271 citations

Amlodipine Releases Nitric Oxide From Canine Coronary Microvessels

1998 • 268 citations

Function and Production of Nitric Oxide in the Coronary Circulation of the Conscious Dog During Exercise

1996 • 190 citations

ACE Inhibitors Promote Nitric Oxide Accumulation to Modulate Myocardial Oxygen Consumption

1997 • 188 citations

The Efficacy and Six-Week Tolerability of Simvastatin 80 and 160 mg/Day

1997 • 168 citations

Sites of prostaglandin synthesis in the bovine heart and isolated bovine coronary microvessels.

1981 • 111 citations

Selective Impairment of Vagally Mediated, Nitric Oxide–Dependent Coronary Vasodilation in Conscious Dogs After Pacing-Induced Heart Failure

1995 • 62 citations

Differential Effects of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Inhibitors on the Development of Myopathy in Young Rats

1996 • 57 citations

Short-term Exercise Training Enhances Reflex Cholinergic Nitric Oxide–Dependent Coronary Vasodilation in Conscious Dogs

1997 • 28 citations