Fortnightly Review Biology and clinical relevance of nitric oxide

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure

1992 • 2,138 citations

Inhaled Nitric Oxide for the Adult Respiratory Distress Syndrome

1993 • 1,811 citations

Nitric Oxide: A Physiologic Mediator of Penile Erection

1992 • 1,187 citations

Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.

1991 • 1,016 citations

Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene

1993 • 881 citations

Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock

1991 • 873 citations

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine

1991 • 813 citations

Pathological implications of nitric oxide, superoxide and peroxynitrite formation

1993 • 679 citations

Arginine: Biochemistry, Physiology, and Therapeutic Implications

1986 • 526 citations

Characterization of the novel nitric oxide synthase inhibitor 7‐nitro indazole and related indazoles: antinociceptive and cardiovascular effects

1993 • 470 citations

Nitric oxide synthase activity in ulcerative colitis and Crohn's disease

1993 • 468 citations

Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle.

1992 • 444 citations

7‐Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti‐nociceptive activity in the mouse without increasing blood pressure

1993 • 426 citations

Identification of increased nitric oxide biosynthesis during pregnancy in rats

1993 • 394 citations

Nitric oxide synthase activities in human myocardium

1993 • 358 citations

Increased nitric oxide synthesis in ulcerative colitis

1993 • 347 citations

Nitric oxide and cardiovascular control

1993 • 178 citations

Effects of S-nitroso-glutathione in the human forearm circulation: evidence for selective inhibition of platelet activation

1994 • 166 citations

Synthesis of nitric oxide from L-arginine: a recently discovered pathway induced by cytokines with antitumour and antimicrobial activity

1991 • 153 citations

Role of endogenous nitric oxide in septic shock.

1993 • 131 citations

Endothelium, endocardium, and cardiac contraction

1992 • 38 citations

Inhibition by N^ω‐nitro‐L‐arginine methyl ester of the electrocortical arousal response in rats

1993 • 37 citations