The Interaction of the LH/hCG Receptor with Adenylate Cyclase in the Rat Ovary

The Determination of Enzyme Dissociation Constants

1934 • 11,865 citations

The Fluid Mosaic Model of the Structure of Cell Membranes

1972 • 8,835 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 811 citations

Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site

1977 • 726 citations

Hormonal regulation of peptide receptors and target cell responses

1979 • 531 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 519 citations

Adenylate cyclase assay.

1979 • 485 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 469 citations

GTP-binding proteins in membranes and the control of adenylate cyclase activity.

1977 • 456 citations

Granulosa Cell Maturation in the Rat: Increased Binding of Human Chorionic Gonadotropin Following Treatment with Follicle-Stimulating Hormonein Vivo¹¹

1974 • 398 citations

Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP.

1978 • 372 citations

Mode of coupling between the β-adrenergic receptor and adenylate cyclase in turkey erythrocytes

1978 • 347 citations

Protein Hormone Action: A Key to Understanding Ovarian Follicular and Luteal Cell Development

1976 • 337 citations

Role of Cyclic Amp in Cell Function

1970 • 317 citations

Hormone-stimulated desensitization of hormone-dependent adenylyl cyclase. Dual action of luteninizing hormone on pig graafian follicle membranes.

1976 • 244 citations

5′-Guanylylimidodiphosphate, A Potent Activator of Adenylate Cyclase Systems in Eukaryotic Cells

1974 • 244 citations

Coupling of catecholamine receptor from one cell with adenylate cyclase from another cell by cell fusion.

1976 • 240 citations

Ovarian Follicular and Corpus Luteum Function

1979 • 225 citations

Gonadotropin Action on Cultured Graafian Follicles: Induction of Maturation Division of the Mammalian Oocyte and Differentiation of the Luteal Cell

1974 • 223 citations

Hormone-sensitive adenylyl cyclases useful models for studying hormone receptor functions in cell-free systems

1973 • 219 citations

Adenylyl Cyclase Activities in Ovarian Tissues. I. Homogenization and Conditions of Assay in Graafian Follicles and Corpora Lutea of Rabbits, Rats, and Pigs: Regulation by ATP, and Some Comparative Properties

1976 • 218 citations

The Role of Cyclic AMP in Gonadal Steroidogenesis1

1976 • 215 citations

Mode of coupling between hormone receptors and adenylate cyclase elucidated by modulation of membrane fluidity

1978 • 202 citations

Stimulatory and Inhibitory Effects of Guanyl Nucleotides on Fat Cell Adenylate Cyclase

1973 • 198 citations

ACTION OF PROSTAGLANDIN E2 AND OF LUTEINIZING HORMONE ON OVARIAN ADENYLATE CYCLASE, PROTEIN KINASE AND ORNITHINE DECARBOXYLASE ACTIVITY DURING POSTNATAL DEVELOPMENT AND MATURITY IN THE RAT

1973 • 196 citations

The hepatic adenylate cyclase system. I. Evidence for transition states and structural requirements for guanine nucloetide activiation

1975 • 171 citations

Reconstitution of catecholamine-sensitive adenylate cyclase. Reconstitution of the uncoupled variant of the S40 lymphoma cell.

1979 • 171 citations

Quantitative determination of the lateral diffusion coefficients of the hormone-receptor complexes of insulin and epidermal growth factor on the plasma membrane of cultured fibroblasts.

1978 • 148 citations

Isoproterenol-induced desensitization of adenylate cyclase in human astrocytoma cells. Relation of loss of hormonal responsiveness and decrement in beta-adrenergic receptors.

1979 • 142 citations

Adenylyl Cyclase Activities in Ovarian Tissues. II. Regulation of Responsiveness to LH, FSH, and PGE₁in the Rabbit

1976 • 136 citations

Role of adenine and guanine nucleotides in the activity and response of adenylate cyclase systems to hormones: evidence for multisite transition states.

1975 • 133 citations

Mechanism of action of luteinizing hormone and follicle-stimulating hormone on the ovary in vitro

1977 • 123 citations

Binding of Gonadotropins to Ovarian Cells

1974 • 118 citations

Hormonal regulation of membrane receptors and cell responsiveness: A review

1978 • 117 citations

On the mechanism of activation of fat cell adenylate cyclase by guanine nucleotides. An explanation for the biphasic inhibitory and stimulatory effects of the nucleotides and the role of hormones.

1975 • 106 citations

Beta adrenergic receptors and adenylate cyclase: products of separate genes?

1976 • 98 citations

Intraovarian factors in ovulation: determinants of follicular response to gonadotrophins

1977 • 90 citations

Molecular Mechanisms of Biological Recognition

1980 • 88 citations

Basic Concepts of the Mechanism of Action of Peptide Hormones

1976 • 85 citations

Internalization and degradation of receptor-bound hCG in granulosa cell cultures.

1979 • 81 citations

Evidence for specific binding sites for guanine nucleotides in adipocyte and hepatocyte plasma membranes. A difference in fate of GTP and guanosine 5'-(beta, gamma-imino) triphosphate.

1975 • 79 citations

The regulatory GTPase cycle of turkey erythrocyte adenylate cyclase.

1977 • 78 citations

Mechanism of desensitization of adenylate cyclase in lutropin. GTP-dependent uncoupling of the receptor.

1980 • 74 citations

In vitro induction of binding sites for hCG in rat granulosa cells by FSH

1977 • 73 citations

The Porcine Ovarian Follicle: III. Development of Chorionic Gonadotropin Receptors Associated with Increase in Adenyl Cyclase Activity During Follicle Maturation

1976 • 69 citations

Adenylate Cyclase Activity in Adrenocorticotropic Hormone-sensitive and Mutant Adrenocortical Tumor Cell Lines

1972 • 69 citations

Receptor regulation and target cell responses: Studies in the ovarian luteal cell

1978 • 64 citations

The effect of catecholamines on the adenyl cyclase of frog and tadpole hemolysates

1968 • 62 citations

Refractoriness of ovarian adenylate cyclase to continued hormonal stimulation

1976 • 61 citations

Interactions of Gonadotropins with Corpus Luteum Membranes. I. Properties and Distributions of Some Marker Enzyme Activities after Subcellular Fractionation of the Superovulated Rat Ovary*

1978 • 53 citations

Isoproterenol-induced desensitization of adenylate cyclase responsiveness in a cell-free system.

1979 • 52 citations

Appearance of LH-receptors and LH-stimulable cyclic AMP accumulation in granulosa cells during follicular maturation in the rat ovary

1977 • 51 citations

Mechanism of hormonally induced refractoriness of ovarian adenylate cyclase to luteinizing hormone and prostaglandin E.

1977 • 47 citations

Molecular mechanisms of activation and desensitization of adenylate cyclase coupled beta-adrenergic receptors.

1978 • 43 citations

Resensitization of the Desensitized Follicular Adenylyl Cyclase System to Luteinizing Hormone*

1979 • 41 citations

BINDING OF LUTEINIZING HORMONE AND HUMAN CHORIONIC GONADOTROPHIN TO OVARIAN CELLS AND ACTIVATION OF ADENYLATE CYCLASE

1974 • 37 citations

Properties of LH-sensitive adenylate cyclase in purified plasma membranes from rat ovary

1978 • 37 citations

On the development and properties of the brain adenyl cyclase system.

1970 • 36 citations

Beta-adrenergic receptors, cyclic AMP, and ion transport in the avian erythrocyte.

1975 • 31 citations

Studies on the Receptor for Luteinizing Hormone in a Purified Plasma Membrane Preparation from Rat Ovary*

1980 • 28 citations

Hormone-sensitive adenylate cyclase: resolution and reconstitution of some components necessary for regulation of the enzyme.

1978 • 19 citations

Synchronous generation of ovarian hCG binding sites and LH-sensitive adenylate cyclase in immature rats following treatment with pregnant mare serum gonadotropin.

1977 • 17 citations

Interactions of gonadotropins with corpus luteum membranes

1978 • 16 citations

Gonadal luteinizing hormone receptors and adenylate cyclase: transfer of functional ovarian luteinizing hormone receptors to adrenal fasciculata cells.

1978 • 16 citations

[Properties of the adenyl cyclase systems in liver and adipose cells: the mode of action of hormones].

1970 • 14 citations

Effect of modulators of cytoskeletal function on desensitization and recovery of PGE2-responsive ovarian adenylate cyclase

1979 • 12 citations

Evidence for Specific Binding Sites for Guanine Nucleotides in Adipocyte and Hepatocyte Plasma Membranes

1975 • 11 citations

Lutropin Induced Desensitization of Rat Ovarian Adenylate Cyclase: A GTP-Dependent Process

1979 • 2 citations

Mechanism and Significance of Luteal Desensitization: Chairman’s Concluding Remarks

1979 • 2 citations

Photo-induced inactivation and uncoupling of gonadotropin receptors in rat ovarian plasma membrane

1980 • 1 citations

ADENYLATE CYCLASE IN THE IMMATURE RAT OVARY

1978 • 1 citations