Establishment of ‘normal’ nervous cell lines after transfer of polyoma virus and adenovirus early genes into murine brain cells.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

1979 • 2,285 citations

Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence

1972 • 1,456 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

Galactocerebroside is a specific cell-surface antigenic marker for oligodendrocytes in culture

1978 • 813 citations

Clonal cell lines from the rat central nervous system

1974 • 727 citations

A new dominant hybrid selective marker for higher eukaryotic cells

1981 • 662 citations

Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

1981 • 657 citations

Uptake and metabolism of γ-aminobutyric acid by neurones and glial cells

1975 • 564 citations

Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein

1981 • 435 citations

Glia are a unique substrate for the in vitro growth of central nervous system neurons

1984 • 425 citations

The roles of individual polyoma virus early proteins in oncogenic transformation

1982 • 366 citations

Glial heterogeneity may define the three-dimensional shape of mouse mesencephalic dopaminergic neurones

1984 • 326 citations

Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines.

1983 • 240 citations

Defective transforming capacity of adenovirus type 5 host-range mutants

1978 • 211 citations

Biochemical and Ultrastructural Studies of Cultured Rat Astroglial Cells

1980 • 166 citations

Construction and functional characterization of polyomavirus genomes that separately encode the three early proteins

1984 • 108 citations

Astrocytic cell clones derived from established cultures of 8-day postnatal mouse cerebella

1984 • 105 citations

Expression of cell adhesion molecules during embryogenesis and regeneration

1985 • 100 citations

The relationship between region E1a and E1b of human adenoviruses in cell transformation

1982 • 91 citations

The E4 transcilpilonal unit of Ad2: far upstream sequences are required for its transactivation by E1A

1984 • 86 citations

A neuronal clone derived from a Rous sarcoma virus-transformed quail embryo neuroretina established culture

1983 • 70 citations

Establishment of a Clone of Mouse Hypothalamic Neurosecretory Cells Synthesizing Neurophysin and Vasopressin

1974 • 68 citations

Behaviour of neuroblasts in the presence of glial cells, fibroblasts and meningeal cells in culture

1974 • 60 citations

Astroglial proliferation and phenotype are modulated by neuronal plasma membrane

1984 • 47 citations

Amplification and excision of integrated polyoma DNA sequences require a functional origin of replication

1984 • 46 citations

Site-specific excision of integrated polyoma DNA

1984 • 42 citations

Two simian virus 40 (SV40)-transformed cell lines from the mouse striatum and mesencephalon presenting astrocytic characters. II. Interactions with mesencephalic neurons

1986 • 26 citations

[19] Techniques for culture of hypothalamic neurons

1983 • 19 citations