Antigenic Determinants of Proteins of Defined Sequences

Atlas of protein sequence and structure

1965 • 4,462 citations

Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution

1965 • 1,623 citations

AUTOMATION IN ANALYTICAL CHEMISTRY

1967 • 980 citations

Nonenzymatic Cleavage of Peptide Bonds: The Methionine Residues in Bovine Pancreatic Ribonuclease

1962 • 929 citations

Antibodies to Bradykinin and Angiotensin: A Use of Carbodiimides in Immunology

1964 • 820 citations

The Amino Acid Sequence of Egg White Lysozyme

1963 • 726 citations

The Preparation of Subtilisin-modified Ribonuclease and the Separation of the Peptide and Protein Components

1959 • 632 citations

Atlas of Protein Sequence and Structure 1969

1970 • 623 citations

Tertiary Structure of Ribonuclease

1967 • 573 citations

The Sequence of Amino Acid Residues in Bovine Pancreatic Ribonuclease: Revisions and Confirmations

1963 • 562 citations

Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells.

1954 • 545 citations

A Partial Determination by X-ray Methods, and its Correlation with Chemical Data

1961 • 486 citations

Conformation of Biopolymers

1967 • 463 citations

Book Review: Treatise on Collagen

1969 • 442 citations

Structure and function of haemoglobin

1965 • 440 citations

Cytochrome c

1966 • 428 citations

Antigenicity: Some Molecular Aspects

1969 • 418 citations

Amino-Acid Sequence of Sperm Whale Myoglobin

1965 • 395 citations

Die Konstitution des normalen adulten Humanhämoglobins

1961 • 386 citations

Margaret O. Dayhoff: Atlas of Protein Sequence and Structure 1969 (Volume 4) XXIV u. 361 S., 21 Ausklapptafeln, 68 Abb. und zahlreiche Tabellen. National Biomedical Research Foundation, Silver Spring/Maryland 1969. Preis $ 12,50

1971 • 353 citations

Micromethods for the Study of Proteins and Antibodies

1954 • 352 citations

The Structure of Ribonuclease-S at 3.5 A Resolution

1967 • 351 citations

Structure Of Hæemoglobin: A Three-Dimensional Fourier Synthesis of Reduced Human Haemoglobin at 5.5 Å Resolution

1963 • 328 citations

THE PREPARATION, PURIFICATION, AND AMINO ACID SEQUENCE OF A POLYPEPTIDE RENIN SUBSTRATE

1957 • 320 citations

New X-Ray Evidence on the Configuration of Polypeptide Chains: Polypeptide Chains in Poly-γ-benzyl-L-glutamate, Keratin and Hæmoglobin

1951 • 313 citations

Amino-Acid Sequence of Human Insulin

1960 • 304 citations

Immunologic Specificity and Molecular Structure

1963 • 301 citations

Immunochemical Studies with Synthetic Human Gastrin

1968 • 296 citations

Structural concepts in immunology and immunochemistry

1968 • 283 citations

The Disulfide Bonds of Egg White Lysozyme (Muramidase)

1965 • 258 citations

The correlation of ribonuclease activity with specific aspects of tertiary structure

1957 • 237 citations

The Nature of an Antigenic Determinant

1966 • 217 citations

Immunological Studies with Synthetic Polypeptides

1966 • 209 citations

Immunochemistry of sperm whale myoglobin. I. Specific interaction of some tryptic peptides and of peptides containing all the reactive regions of the antigen

1968 • 200 citations

Antigenicity of insulin: diabetes induced by specific antibodies

1955 • 196 citations

X-Ray and Solubility Studies of the Hæmoglobin of Sickle-Cell Anæmia Patients

1951 • 189 citations

The Amino Acid Sequence of Clostridium pasteurianum Ferredoxin^*

1966 • 187 citations

Isolation and amino acid sequence of caerulein, the active decapeptide of the skin of Hyla caerulea

1968 • 186 citations

Antibodies to biologically active molecules

1967 • 177 citations

THE COMPLETE AMINO ACID SEQUENCE OF THE PROTEIN OF TOBACCO MOSAIC VIRUS

1960 • 172 citations

Immunochemical approaches to problems in microbiology

1961 • 164 citations

Primary Structure of the Protein of Tobacco Mosaic Virus

1960 • 159 citations

Antibodies to Sequential and Conformational Determinants

1967 • 157 citations

Polymers of tripeptides as collagen models

1966 • 152 citations

Plant Virus Serology

1967 • 150 citations

The structure of bradykinin — A plasma kinin from ox blood

1960 • 148 citations

The structural basis of antibody specificity

1968 • 142 citations

SPECIES-SPECIFICITY OF HUMAN ANTI-BEEF, PORK INSULIN SERUM

1959 • 137 citations

Enzymic and immunochemical properties of lysozyme. Evaluation of several amino group reversible blocking reagents

1970 • 134 citations

The antral Hormone Gastrin: Synthesis of Gastrin

1964 • 134 citations

The structural basis of antibody specificity

1968 • 131 citations

STUDIES ON THE ACTION OF CARBOXYPEPTIDASE ON TOBACCO MOSAIC VIRUS

1955 • 127 citations

Preparation and properties of an artificial antigen immunologically related to tobacco mosaic virus

1963 • 125 citations

ANTIBODIES TO A UNIQUE REGION IN LYSOZYME PROVOKED BY A SYNTHETIC ANTIGEN CONJUGATE

1969 • 124 citations

Immunological Activity of Cytochrome c

1970 • 122 citations

Immunochemistry of sperm-whale myoglobins prepared with various modified porphyrins and metalloporphyrins

1967 • 118 citations

Periodate oxidation of sperm-whale myoglobin and the role of the methionine residues in the antigen-antibody reaction

1967 • 115 citations

The immunological activity of some of the chymotryptic peptides of sperm-whale myoglobin

1965 • 114 citations

Isolation of aspartyl-phenylalanine amide from cholecystokinin-pancreozymin

1967 • 112 citations

Studies on the Antigenic Structure of Ribonuclease

1959 • 100 citations

Conformational changes in sperm-whale metmyoglobin due to combination with antibodies to apomyoglobin

1966 • 97 citations

Structure and function of hemoglobin.

1969 • 96 citations

Polymers of tripeptides as collagen models

1966 • 96 citations

Chemical and immunological characterization of a unique antigenic region in lysozyme

1971 • 95 citations

Properties of different artificial antigens immunologically related to tobacco mosaic virus

1965 • 92 citations

Quantitative Immunological Comparison of Bird Lysozymes

1967 • 91 citations

Immunochemistry of sperm whale myoglobin. IV. Role of the arginine residues in the conformation and differentiation of their roles in the antigenic reactivity

1969 • 90 citations

Induction of Antibodies to Porcine ACTH in Rabbits with Nonsteroidogenic Polymers of BSA and ACTH

1968 • 88 citations

Immunological Prediction of Sequence Differences among Proteins

1969 • 87 citations

Synthesis of Antigenic Branch-Chain Copolymers of Angiotensin and Poly-L-lysine^*

1965 • 86 citations

STUDIES ON THE IMMUNE RESPONSE TO A CHARACTERIZED ANTIGENIC DETERMINANT OF THE TOBACCO MOSAIC VIRUS PROTEIN

1970 • 85 citations

Antibodies to human A1 hemoglobin and their reaction with A2, S, C, and H hemoglobins

1964 • 84 citations

Immunological Activity of Cytochrome c

1970 • 84 citations

Studies on the Antigenic Structure of Ribonuclease

1962 • 81 citations

On the Non‐Essentiality of Two Specific Disulphide Bonds in Ribonuclease for its Biological Activity

1967 • 80 citations

On the Structure of Human Corticotropin (Adrenocorticotropic Hormone)

1961 • 76 citations

Structure of hemoglobin.

1960 • 74 citations

Enzymic and immunochemical properties of lysozyme

1971 • 72 citations

Combining sites of antibodies with l-alanine and d-alanine peptide specificity and the effect of serum proteolytic activity on their estimation

1966 • 72 citations

Human Gastrin: Isolation, Structure and Synthesis: Structures of Human Gastrins I and II

1966 • 71 citations

Immunochemical Studies on the Poly-γ-D-glutamyl Capsule of Bacillus anthracis. II. The Synthesis of Eight Dipeptides and Four Tripeptides of Glutamic Acid^*

1966 • 71 citations

Antigens in Insulin Determinants of Specificity of Porcine Insulin in Man

1963 • 70 citations

Immunochemistry of sperm whale myoglobin. III. Modification of the three tyrosine residues and their role in the conformation and differentiation of their roles in the antigenic reactivity

1968 • 70 citations

Immunochemical studies on lysozyme and carboxymethylated lysozyme

1970 • 69 citations

Versuche zur Bestimmung der serologisch determinanten Gruppen des Tabakmosaikvirus

1963 • 66 citations

Memorial lecture: the isolation and chemistry of gastrin.

1966 • 62 citations

Immunologic Studies of Adrenocorticotropic Hormone (ACTH): Dissociation of Biologic and Immunologic Activities

1965 • 62 citations

Immunochemical studies on the tobacco mosaic virus protein. VI. Characterization of antibody populations following immunization with tobacco mosaic virus protein

1968 • 61 citations

Memorial Lecture: The Isolation and Chemistry of Gastrin

1966 • 61 citations

Immunochemistry of sperm whale of myoglobin. IX. Specific interaction of peptides obtained by cleavage at arginine peptide bonds

1971 • 60 citations

Studies on Polypeptides. XXXIII. Enzymic Properties of Partially Synthetic Ribonucleases^1-4

1965 • 60 citations

Enzymic and immunochemical properties of lysozyme — II.

1969 • 60 citations

Antigenic properties of egg-white lysozyme. I. Isolation and characterization of a tryptic peptide from reduced and alkylated lysozyme exhibiting haptenic activity

1968 • 59 citations

Immunochemical Studies on the Tobacco Mosaic Virus Protein. I. The Immunological Relationship of the Tryptic Peptides of Tobacco Mosaic Virus Protein to the Whole Protein^*

1964 • 58 citations

Antibodies to the Carboxyl-Terminal Tetrapeptide of Gastrin

1967 • 58 citations

Immunochemical studies of angiotensin

1966 • 58 citations

The Reactions of Antibodies with Hemeprotein Antigens

1969 • 58 citations

Immunochemical Studies of Hemoglobin and Myoglobin and Their Globin Moieties

1963 • 57 citations

THE PRODUCTION OF HIGH-TITRE ANTIBODY AGAINST FREE ANGIOTENSIN II

1968 • 57 citations

Immunochemical studies on the tobacco mosaic virus protein. VII. Binding of octanoylated peptides of the tobacco mosaic virus protein with antibodies to the whole protein

1968 • 56 citations

Identification of the chemical difference between chromatographic components of ribonuclease

1956 • 55 citations

Immunochemistry of sperm whale myoglobin. II. Modification of the two tryptophan residues and their role in the conformation and antigen-antibody reaction

1968 • 54 citations

Production of Antibody against Bradykinin: Demonstration of Specificity by Complement Fixation and Radio-Immunoassay

1966 • 54 citations

Immunochemical Studies on the Tobacco Mosaic Virus Protein. II. The Specific Binding of a Tryptic Peptide of the Protein with Antibodies to the Whole Protein^*

1965 • 53 citations

Immunology Conformation and Biological Activity of Insulin

1969 • 52 citations

Immunochemical Studies on Tobacco Mosaic Virus Protein. V. The Solid-Phase Synthesis of Peptides of an Antigenically Active Decapeptide of Tobacco Mosaic Virus Protein and the Reaction of These Peptides with Antibodies to the Whole Protein^*

1967 • 51 citations

Immunochemical resemblance between human leukemia and hen egg-white lysozyme and their reduced carboxymethyl derivatives

1971 • 51 citations

Immunochemical specificity: Recent conceptual advances

1969 • 50 citations

The Interaction Between Bovine Ribonuclease and Antibody: A Study of the Mechanism of Enzyme Inhibition by Antibody

1961 • 47 citations

Studies on the chemical basis of the antigenicity of proteins. 3. The role of rigidity in the antigenicity of polypeptidyl gelatins

1960 • 47 citations

Reaginic Antibody against Insulin: Demonstration of Antigenic Distinction between Native and Extracted Insulin

1969 • 47 citations

A specific antibody-hapten reaction with novel spectral properties

1963 • 47 citations

Immunological and biological properties of iodoinsulin labeled with one or less atoms of iodine per molecule

1968 • 46 citations

IMMUNOCHEMICAL REACTIONS INVOLVING RIBONUCLEASE*

1959 • 46 citations

Immunochemical Studies on Tobacco Mosaic Virus Protein. IV. The Automated Solid-Phase Synthesis of a Decapeptide of Tobacco Mosaic Virus Protein and Its Reaction with Antibodies to the Whole Protein^*

1966 • 45 citations

Studies of the Immunochemical I Specificity of Some Antibodies to Human Gastrin

1969 • 45 citations

The properties and interactions of the isolated α- and β-chains of human haemoglobin

1966 • 45 citations

ANTIBODY AS INHIBITOR OF RIBONUCLEASE: THE ROLE OF STERIC HINDRANCE, AGGREGATE FORMATION, AND SPECIFICITY

1963 • 44 citations

A Selective Fractionation of Anti-Lysozyme Antibodies of Different Determinant Specificities

1968 • 43 citations

The Antigenic Structure of Tobacco Mosaic Virus

1965 • 42 citations

The Amino Acid Sequence of Human Heart Cytochrome c

1962 • 42 citations

The immunochemical difference between horse oxy- and deoxyhaemoglobin

1964 • 41 citations

Antibodies against the Component Polypeptide Chains of Bovine Insulin

1965 • 40 citations

Studies on the Antigenic Structure of Ribonuclease

1963 • 40 citations

Immunochemical analysis of rabbit antibodies against angiotensin II

1967 • 40 citations

Enzyme activation by antibody. I. Fractionation of immune sera in search for an enzyme activating antibody.

1969 • 39 citations

The specificity of antibodies to a peptide determinant of the tobacco mosaic virus protein induced by immunization with the peptide conjugate

1971 • 38 citations

IMMUNOLOGIC PRODUCTION OF ANTIANGIOTENSIN

1960 • 37 citations

Structural basis for immune recognition of lysozymes. I. Effect of cyanogen bromide on hen egg-white lysozyme

1969 • 37 citations

Immunochemistry of sperm-whale myoglobin

1973 • 35 citations

Tolerance Induction by an Apparently Non-immunogenic Molecule

1970 • 34 citations

Genetic differences of combining sites of insulin antibodies and importance of C-terminal portion of the A chain to biological and immunological activity of insulin

1966 • 34 citations

Immunochemical studies on tobacco mosaic virus protein. IX. Binding and antigenic specificity of antibodies to an antigenic area of tobacco mosaic virus protein

1969 • 33 citations

Structural Requirements for Binding to Antibody of Sequence Variants of Bradykinin^*

1967 • 32 citations

The reaction of porcine and ovine ribonucleases with antibody to bovine ribonuclease

1960 • 32 citations

Immunochemical studies on the poly-γ-D-glutamyl capsule of Bacillus anthracis. III. Activity with rabbit antisera of peptides derived from the homologous polypeptide

1968 • 32 citations

Immunochemistry of sperm whale myoglobin. VIII. Specific interaction of peptides obtained by cleavage at proline peptide bonds

1970 • 31 citations

Effect of rabbit antibodies against angiotensin‐II on the pressor response to angiotensin‐II and renal hypertension in the rat

1968 • 31 citations

Studies on the Nature of Antigenicity of A and B Chains of Bovine Insulin^*

1967 • 31 citations

THE ANTIGENICITY OF SOME SYNTHETIC POLY-IMINOACIDS. I. ANTIGENIC PROPERTIES OF POLY-L-PROLINE.

1965 • 30 citations

Studies on the Antigenic Structure of Ribonuclease

1960 • 30 citations

Immunological comparison of bird and human lysozymes and of their “loop” regions

1970 • 29 citations

Antibodies to the C-Terminal Tetrapeptide Amide of Gastrin

1968 • 28 citations

Effect of modification of insulin on specific binding in insulin-resistant sera

1959 • 28 citations

Aminos�ureaustausche und Terti�rstruktur eines Proteins

1965 • 28 citations

The Interaction of Subtilisin-modified Ribonuclease with Antisera against Native Ribonuclease

1959 • 28 citations

An Antigenic Site of Sperm Whale Myoglobin

1967 • 28 citations

A Sensitive Technique for Detecting and Estimating the Peptide Hormone Angiotensin‐II‐β‐amide and its Antibodies by Using Chemically Modified Bacteriophage and Activated Sepharose

1970 • 28 citations

Enzyme Activation by Antibody

1969 • 27 citations

Studies of ACTH Antibodies and Their Reactions with Inactive Analogues of ACTH

1966 • 27 citations

Immunochemistry of sperm whale myoglobin—V. Specific modification of the methionine residues with β-propiolactone

1969 • 27 citations

Enzyme-activation by antibody. II. The distribution of activating antibody in chromatographic fractions of ribonuclease antisera and their competition with inhibiting antibody for enzyme sites.

1970 • 26 citations

The role of α and β chains in the immunochemical difference between oxy and deoxy human haemoglobin

1965 • 26 citations

Role of the Amino Groups and C-Terminal of Sperm-Whale Myoglobin in the Antigen–Antibody Reaction

1966 • 24 citations

Immunochemical Studies on the Tobacco Mosaic Virus Protein. III. The Degradation of an Immunologically Active Tryptic Peptide of Tobacco Mosaic Virus Protein and the Reactivity of the Degradation Products with Antibodies to the Whole Protein^*

1966 • 24 citations

Antibodies to Rabbit CytochromecArising in Rabbits

1967 • 23 citations

Antibodies to Synthetic Corticotrophin

1966 • 23 citations

The Effect on Antigenic Specificity of Changes in the Molecular Structure of Ribonuclease

1963 • 22 citations

Antigenicity of Synthetic Polypeptides with known Amino-Acid Sequence

1963 • 22 citations

THE ANTIGENIC LOCI OF INSULIN

1967 • 22 citations

Immunological studies on the major haptenic peptides from performic acid oxidized ferredoxin from Clostridium pasteurianum

1971 • 21 citations

IMMUNOLOGIC PRODUCTION OF ANTIANGIOTENSIN

1960 • 21 citations

The antigenicity of insulin: A review

1962 • 21 citations

The Immunology of Insulin

1966 • 21 citations

Immunochemical studies on the tobacco mosaic virus protein. VIII. Solid-phase synthesis and immunological activity of peptides related to an antigenic area of tobacco mosaic virus protein

1968 • 21 citations

GENERATION AND USE OF ANTIBODIES TO ANGIOTENSIN II

1967 • 21 citations

IMMUNOLOGIC STUDIES OF BOVINE RIBONUCLEASE DERIVATIVES*

1963 • 20 citations

Radioimmunoassay of Angiotensin

1968 • 20 citations

Structure and Function of Antigen and Antibody Proteins

1965 • 20 citations

THE ANTIGENIC PROPERTIES OF SOME SYNTHETIC POLY-IMINOACIDS. II. THE ANTIGENICITY OF POLYPEPTIDES RELATED TO COLLAGEN; PEPTIDES CONTAINING HYDROXYPROLINE AND ACETYL-HYDROXY-PROLINE.

1965 • 20 citations

The Relationship Between Antigenic Structure and Immune Specificity

1972 • 19 citations

The C-terminal antigenic site of sperm-whale myoglobin: the immunological activities of synthetic peptides related to the C-terminus of myoglobin

1970 • 19 citations

A common size parameter for hydrophobic binding of inhibitors by α-Chymotrypsin, alkylated α-Chymotrypsin, and yeast alcohol dehydrogenase

1968 • 19 citations

Conformational changes in the antigenic determinant of tobacco mosaic virus protein resulting from polymerization of the subunits

1970 • 18 citations

Antigenicity of hemoglobin and its constituents

1964 • 18 citations

Structural requirements for binding of bradykinin to antibody. II. Studies with bradykinin fragments

1968 • 18 citations

IMMUNOCHEMICAL STUDIES OF INSULIN

1960 • 18 citations

Hypersensitivity to Peptide Fragments

1967 • 18 citations

Studies on the Physical, Immunological and Biological Properties of Insulin Conjugated with Fluorescein Isothiocyanate

1961 • 18 citations

Die Reihenfolge der Aminosäuren im Protein des Tabakmosaikvirus

1960 • 18 citations

The distribution of specificity in rabbit antisera directed toward human hemoglobins

1970 • 18 citations

Studies on the antigenicity of bacterial ferredoxins. I. The effect of modification of cysteinyl residues on the antigenicity of Clostridium pasteurianum ferredoxin.

1969 • 17 citations

Enzyme-Activation by Antibody

1970 • 16 citations

Einfluß der Tertiärstruktur auf die serologischen Eigenschaften des Tabakmosaikvirus

1963 • 16 citations

THE IMMUNOLOGICAL REACTIVITY AND BIOLOGICAL ACTIVITY OF IODINATED INSULIN

1968 • 16 citations

Immunochemical study of β-corticotropin-(1–24)-tetracosa-peptide

1968 • 16 citations

Failure of Guinea Pig Antibody to Beef Insulin to Neutralize Coypu (Nutria) Insulin

1968 • 16 citations

Structural studies of pancreatic ribonuclease.

1967 • 15 citations

The synthesis and immunological activity of a peptide related to collagen

1967 • 15 citations

Synthesis of haptenic C-terminal octapeptides of two cross-reacting bacterial ferredoxin molecules

1970 • 14 citations

Properties and interactions of the isolated α and β chains of human haemoglobin

1965 • 14 citations

Antigenicity of the β-Chain of Human Hæmoglobin

1964 • 14 citations

Failure of Guinea Pig Antibodies to Beef Insulin, Chicken Insulin, and Cod Insulin to Neutralize Capybara Insulin

1969 • 14 citations

Biologically effective immunization against angiotensin

1968 • 14 citations

The Essential Role of Specific Conformation in the Antigenicity of Ribonuclease^*

1966 • 13 citations

Chemical studies on antigenic determinants of hen egg white lysozyme. I.

1967 • 13 citations

The tertiary structure of ribonuclease.

1962 • 12 citations

Comparative studies on the chemistry of collagen utilizing cyanogen bromide cleavage.

1968 • 12 citations

Studies on the Antigenicity of Bacterial Ferredoxins

1969 • 12 citations

Interaction of a peptide with antibody to oxidized ribonuclease

1970 • 11 citations

The Analysis of the Antigenic Structure of Protein Molecules

2015 • 11 citations

Structural basis for immune recognition of lysozymes. II. Reactive but non-immunogenic epitopes

1971 • 11 citations

Immunological Studies of the A and B Chains of Insulin

1970 • 10 citations

Studies on the Antigenic Structure of Ribonuclease

1967 • 10 citations

Antigenic structures of hen egg white lysozyme. II. Significance of the N-and C-terminal region as an antigenic site.

1968 • 10 citations

Binding of caerulein by antibodies to human gastrin I

1969 • 10 citations

Antigenic determinants in human hemoglobin: the alpha polypeptide chain.

1967 • 8 citations

FAILURE OF GUINEA PIG ANTIBODY TO BEEF INSULIN TO NEUTRALIZE PANCREATIC AND SERUM GUINEA PIG INSULIN ACTIVITY IN VITRO

1965 • 8 citations

Analysis of Antibodies against Synthetic Angiotensin II by the Passive Haemagglutination Technique

1968 • 8 citations

Delayed-Type Hypersensitivity to Synthetic Antigens

1968 • 8 citations

Binding of caerulein by antibodies to human gastrin I.

1969 • 8 citations

Antigenic Determinants in Human Hemoglobin: The α Polypeptide Chain

1967 • 7 citations

The immunologic role of methionine and cysteine residues in ribonuclease

1968 • 7 citations

Darstellung und Nachweis von Antik�rpern gegen �1?24

1965 • 7 citations

Antigenicity of the Peptide Chains Isolated from Human Hemoglobins A and F.

1965 • 6 citations

Localisation of Antibody-binding Sites on Insulin Molecules

1969 • 5 citations

Die Reihenfolge der Aminosäuren im Protein des Tabakmosaikvirus

1962 • 5 citations

[Cross-reaction of antoangiotensin II antibiodies with other analogs of angiotensin].

1969 • 4 citations

Antigenic Determinants of Hen Egg White Lysozyme

1967 • 3 citations

The immunological activity of chymotryptic peptides of sperm-whale myoglobin.

1964 • 2 citations