Sickle erythrocytes adhere to polymorphonuclear neutrophils and activate the neutrophil respiratory burst

Mortality In Sickle Cell Disease -- Life Expectancy and Risk Factors for Early Death

1994 • 3,225 citations

Effect of Hydroxyurea on the Frequency of Painful Crises in Sickle Cell Anemia

1995 • 2,210 citations

Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

1983 • 1,808 citations

Pain in Sickle Cell Disease

1991 • 1,510 citations

ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18).

1990 • 898 citations

Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke.

1992 • 617 citations

Mechanics of Stimulated Neutrophils: Cell Stiffening Induces Retention in Capillaries

1989 • 612 citations

Simulation of cell rolling and adhesion on surfaces in shear flow: general results and analysis of selectin-mediated neutrophil adhesion

1992 • 540 citations

In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury.

1993 • 452 citations

Stroke in a cohort of patients with homozygous sickle cell disease

1992 • 429 citations

Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia [see comments]

1992 • 422 citations

Effect of flow on polymorphonuclear leukocyte/endothelial cell adhesion

1987 • 376 citations

Inhibition of polymorphonuclear leukocyte adherence suppresses no-reflow after focal cerebral ischemia in baboons.

1992 • 368 citations

Cytokine-activated human endothelial monolayers support enhanced neutrophil transmigration via a mechanism involving both endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1.

1991 • 359 citations

Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia [see comments]

1992 • 296 citations

Alpha 4 beta 1-integrin expression on sickle reticulocytes: vascular cell adhesion molecule-1-dependent binding to endothelium

1993 • 283 citations

Abnormalities in membrane phospholipid organization in sickled erythrocytes.

1981 • 259 citations

Role of CD11/CD18 in shear rate-dependent leukocyte-endothelial cell interactions in cat mesenteric venules.

1991 • 258 citations

Phagocytosis mediated by three distinct Fc gamma receptor classes on human leukocytes.

1990 • 254 citations

Leukocyte—endothelial cell interactions

1992 • 246 citations

Margination of leukocytes in blood flow through small tubes

1984 • 230 citations

The role of the neutrophil and free radicals in ischemic myocardial injury

1989 • 214 citations

Vascular occlusion in sickle cell disease: current concepts and unanswered questions

1991 • 211 citations

Integrin alpha 4 beta 1 and glycoprotein IV (CD36) are expressed on circulating reticulocytes in sickle cell anemia

1993 • 202 citations

Endothelial cell killing by neutrophils. Synergistic interaction of oxygen products and proteases.

1989 • 199 citations

Thrombospondin from activated platelets promotes sickle erythrocyte adherence to human microvascular endothelium under physiologic flow: a potential role for platelet activation in sickle cell vaso-occlusion

1993 • 196 citations

Sickle reticulocytes adhere to VCAM-1

1995 • 194 citations

[9] Separation of lymphocytes, granulocytes, and monocytes from human blood using iodinated density gradient media

1984 • 190 citations

Elevated immunoreactive tumor necrosis factor and interleukin-1 in sickle cell disease.

1992 • 174 citations

Increased adherence of sickled and phosphatidylserine-enriched human erythrocytes to cultured human peripheral blood monocytes.

1985 • 151 citations

Degranulating Stimuli Decrease the Negative Surface Charge and Increase the Adhesiveness of Human Neutrophils

1980 • 113 citations

Endotoxin, interleukin-1, and tumor necrosis factor cause neutrophil-dependent microvascular leakage in postcapillary venules.

1992 • 102 citations

The Biophysics of Sickle Cell Hydroxyurea Therapy

1995 • 96 citations

Sickle erythrocyte-endothelial interactions in microcirculation: the role of von Willebrand factor and implications for vasoocclusion

1993 • 94 citations

Priming of polymorphonuclear neutrophils by tumor necrosis factor alpha in whole blood: identification of two polymorphonuclear neutrophil subpopulations in response to formyl-peptides

1993 • 88 citations

Adhesion of sickle cells to vascular endothelium is critically dependent on changes in density and shape of the cells

1994 • 87 citations

Sickle Cell Anemia and Major Organ Failure

1990 • 78 citations

Effects of hydroxyurea on hemoglobin F and water content in the red blood cells of dogs and of patients with sickle cell anemia

1991 • 72 citations

Rapid Adhesive Responses of Endothelial Cells and of Neutrophils Induced by Leukotriene B4 are Mediated by Leucocytic Adhesion Protein CD18

1990 • 67 citations

CD18-dependent adherence reactions play an important role in the development of the no-reflow phenomenon

1993 • 66 citations

Tumor necrosis factor-alpha regulates expression of receptors for formyl-methionyl-leucyl-phenylalanine, leukotriene B4, and platelet-activating factor. Dissociation from priming in human polymorphonuclear neutrophils.

1991 • 62 citations

Demonstration of endothelial adhesion of sickle cells in vivo: a distinct role for deformable sickle cell discocytes

1992 • 60 citations

Circulating intercellular adhesion molecule-1 levels and neutrophil adhesion in stroke

1993 • 56 citations

White Blood Cell Count and Stroke Incidence and Death

1994 • 53 citations

Studies on phagocytosis in patients with acute bacterial infections.

1989 • 51 citations

Kinetics of granulocyte deformability following exposure to chemotactic stimuli.

1992 • 49 citations

Surface Mol (CD11b/CD18) glycoprotein is up-modulated by neutrophils recruited to sites of inflammation in vivo

1989 • 45 citations

Effect of flow on polymorphonuclear leukocyte/endothelial cell adhesion

1987 • 45 citations

Formation of isotonic Nycodenz gradients for cell separations

1982 • 43 citations

Cell-bound autologous immunoglobulin in erythrocyte subpopulations from patients with sickle cell disease

1985 • 40 citations

Leukotriene B4 induced hyperadhesiveness of endothelial cells for neutrophils

1990 • 38 citations

Rheologic impairment of sickle RBCs induced by repetitive cycles of deoxygenation-reoxygenation

1988 • 37 citations

Leukocyte—endothelial cell interactions

1992 • 32 citations

Erythrocyte/endothelial interactions in the pathogenesis of sickle-cell disease: a "real logical" assessment.

1982 • 27 citations

Leukocyte adhesion molecules and myocardial ischemia

1991 • 26 citations

Some model experiments in hemodynamics: VI. Two-body collisions between blood cells

1981 • 24 citations

Sickling-induced binding of immunoglobulin to sickle erythrocytes

1988 • 23 citations

Inhibition of tumour necrosis factor alpha (TNF-alpha)-induced neutrophil respiratory burst by a TNF inhibitor.

1991 • 19 citations

Thrombospondin from activated platelets promotes sickle erythrocyte adherence to human microvascular endothelium under physiologic flow: a potential role for platelet activation in sickle cell vaso-occlusion

1993 • 17 citations

Radial distribution of white cells in tube flow.

1984 • 16 citations

Phorbol ester causes down-regulation of CD11/CD18-independent neutrophil adherence to endothelium.

1990 • 15 citations

Erythrocyte/endothelial interactions and the vasocclusive severity of sickle cell disease.

1981 • 14 citations

Sickle erythrocyte-endothelial interactions in microcirculation: the role of von Willebrand factor and implications for vasoocclusion

1993 • 10 citations

Demonstration of endothelial adhesion of sickle cells in vivo: a distinct role for deformable sickle cell discocytes

1992 • 10 citations

Interactions between sphered human red cells in tube flow: Technique for measuring the strength of antigen-antibody bonds

1982 • 8 citations

Erythrocyte calcium abnormalities in sickle cell disease.

1981 • 7 citations

SHEAR‐INDUCED COLLISIONS BETWEEN HUMAN BLOOD CELLSa

1983 • 6 citations

Leukocyte aggregation: a possible link between infection and ischemic stroke.

1992 • 5 citations

Cell-bound autologous immunoglobulin in erythrocyte subpopulations from patients with sickle cell disease

1985 • 4 citations

Sickling-induced binding of immunoglobulin to sickle erythrocytes

1988 • 4 citations

Rheologic impairment of sickle RBCs induced by repetitive cycles of deoxygenation-reoxygenation

1988 • 3 citations