Prognostic Factors in Node-Negative Breast Cancer Patients

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian Cancer

1989 • 6,734 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

Histological Grading and Prognosis in Breast Cancer

1957 • 2,897 citations

Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation

1983 • 2,745 citations

A Randomized Clinical Trial Evaluating Tamoxifen in the Treatment of Patients with Node-Negative Breast Cancer Who Have Estrogen-Receptor–Positive Tumors

1989 • 1,471 citations

Effects of Adjuvant Tamoxifen and of Cytotoxic Therapy on Mortality in Early Breast Cancer

1988 • 921 citations

Neu-Protein Overexpression in Breast Cancer

1988 • 860 citations

Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer. An overview of 61 randomized trials among 28,896 women

1988 • 631 citations

Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer.

1989 • 592 citations

HER-2/neu oncogene protein and prognosis in breast cancer.

1989 • 579 citations

Prediction of Relapse or Survival in Patients with Node-Negative Breast Cancer by DNA Flow Cytometry

1989 • 571 citations

Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading.

1988 • 570 citations

OVEREXPRESSION OF THE c-erbB-2 ONCOPROTEIN IN HUMAN BREAST CARCINOMAS: IMMUNOHISTOLOGICAL ASSESSMENT CORRELATES WITH GENE AMPLIFICATION

1987 • 409 citations

A Randomized Clinical Trial Evaluating Sequential Methotrexate and Fluorouracil in the Treatment of Patients with Node-Negative Breast Cancer Who Have Estrogen-Receptor-Negative Tumors

1989 • 400 citations

Prognostic value of histologic grade nuclear components of Scarff-Bloom-Richardson (SBR). An improved score modification based on a multivariate analysis of 1262 invasive ductal breast carcinomas

1989 • 376 citations

Efficacy of Adjuvant Chemotherapy in High-Risk Node-Negative Breast Cancer

1989 • 359 citations

Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1.

1989 • 321 citations

Prolonged Disease-Free Survival after One Course of Perioperative Adjuvant Chemotherapy for Node-Negative Breast Cancer

1989 • 280 citations

Autocrine Growth Stimulation of the MCF 7 Breast Cancer Cells by the Estrogen-Regulated 52 K Protein*

1986 • 273 citations

The importance of histologic grade in long-term prognosis of breast cancer: a study of 1,010 patients, uniformly treated at the Institut Gustave-Roussy.

1987 • 269 citations

Association between high concentrations of Mr 52,000 cathepsin D and poor prognosis in primary human breast cancer.

1989 • 250 citations

Improving the prognostic value of DNA flow cytometry in breast cancer by combining DNA index and S-phase fraction: A proposed classification of DNA histograms in breast cancer

1988 • 226 citations

The long‐term prognostic significance of the thymidine labelling index in breast cancer

1984 • 225 citations

DNA ploidy and survival in breast cancer patients

1987 • 223 citations

Expression of the c‐erbB‐2 protein in normal and transformed cells

1987 • 197 citations

Cell proliferation kinetics in human solid tumors: relation to probability of metastatic dissemination and long-term survival

1989 • 184 citations

Prognostic significance of tumor grade in clinical trials of adjuvant therapy for breast cancer with axillary lymph node metastasis

1986 • 155 citations

Prognostic value of steroid hormone receptors: multivariate analysis of systemically untreated patients with node negative primary breast cancer.

1987 • 150 citations

Assessment of tumor cell kinetics by immunohistochemistry in carcinoma of breast

1987 • 128 citations

Proliferative index of breast carcinoma by thymidine labeling: Prognostic power independent of stage, estrogen and progesterone receptors

1988 • 125 citations

The correlation of growth fractions with histologic grading and lymph node status in human mammary carcinoma

1987 • 124 citations

c-erbB-2 amplification in node-negative human breast cancer.

1989 • 117 citations

Predictive value of nuclear DNA content in breast cancer in relation to clinical and morphologic factors. A retrospective study of 227 consecutive cases

1988 • 117 citations

Comparison of monoclonal antibody Ki-67 reactivity with grade and DNA flow cytometry of breast carcinomas

1988 • 113 citations

Danish Breast Cancer Cooperative Group (DBCG): A description of the register of the nation-wide programme for primary breast cancer

1988 • 107 citations

The relation of flow cytometry to clinical and biologic characteristics in women with node negative primary breast cancer

1989 • 105 citations

An evaluation of immunoreactivity for c-erbB-2 protein as a marker of poor short-term prognosis in breast cancer

1989 • 102 citations

Prognostic significance of the DNA content of human breast cancer

1987 • 100 citations

Cell kinetics as a prognostic indicator in node-negative breast cancer

1989 • 93 citations

Histopathological systems of breast cancer classification: reproducibility and clinical significance.

1983 • 77 citations

Proliferative index, cytosol estrogen receptor and axillary node status as prognostic predictors in human mammary carcinoma.

1986 • 71 citations

Histologic malignancy grading of invasive ductal breast carcinoma. A regression analysis of prognostic factors in low-risk carcinomas from a multicenter trial

1987 • 58 citations

Danish Breast Cancer Cooperative Group--DBCG.

1977 • 55 citations

Factors affecting relapse in node-negative breast cancer. A multivariate analysis including the labeling index

1989 • 51 citations

Prognostic and therapeutic significance of pathological features of breast cancer.

1986 • 50 citations

Prognostic value of nuclear DNA content in breast cancer in relation to tumor size, nodal status, and estrogen receptor content

1989 • 43 citations

K-67 Immunoreactivity in Breast Carcinomas in Relation to Transferrin Receptor Expression, Estrogen Receptor Status and Morphological Criteria

1989 • 31 citations

Estrogen and progesterone receptor profile patterns in primary breast cancer

1983 • 21 citations

Assessment and Presentation of Survival Experience in the Danish Breast Cancer Cooperative Group

1988 • 10 citations

Adjuvant Hormonal Therapy: Whom to Treat

1989 • 2 citations

Deleted Work

1955 • 0 citations