Correlation Between Teratogenic and Mutagenic Effects of Chemicals in Mammals

Biology of the Laboratory Mouse

1941 • 826 citations

Teratology: Principles and Techniques.

1965 • 682 citations

Teratology. Principles and Techniques

1965 • 522 citations

X-RAY-INDUCED MUTATIONS IN MICE

1951 • 486 citations

EMBRYOLOGICAL CONSIDERATIONS IN TERATOLOGY*

1965 • 439 citations

The Chemical Production of Mutations

1947 • 437 citations

Biology of the Laboratory Mouse

1967 • 296 citations

An analysis of the changing radiation response of the developing mouse embryo

1954 • 294 citations

Experimental production of congenital malformations in strains of inbred mice by maternal treatment with hypervitaminosis A.

1961 • 235 citations

Chemical Mutagens in the Human Environment

1968 • 224 citations

Induction of dominant lethal mutations by alkylating agents in male mice

1968 • 212 citations

Teratology of the Central Nervous System

1969 • 156 citations

Teratology of the Central Nervous System

1970 • 142 citations

Congenital Malformations in Offspring of Mice Treated with Caffcine.

1960 • 141 citations

RADIATION-INDUCED PRESUMED SOMATIC MUTATIONS IN THE HOUSE MOUSE

1957 • 139 citations

ANTIFERTILITY SUBSTANCES AND THEIR ASSESSMENT IN THE MALE RODENT

1961 • 136 citations

The teratogenicity of cyclophosphamide in mice.

1968 • 127 citations

Compounds interfering with ovum implantation and development

1966 • 127 citations

Effects of ionizing radiation on the reproductive system

1965 • 122 citations

The mutagenic action of caffeine in higher organisms.

1968 • 121 citations

Congenital defects in guinea pigs: Fetal resorptions, abortions, and malformations following induced hyperthermia during early gestation

1969 • 120 citations

A chemically-induced variegated-type position effect in the mouse

1961 • 120 citations

Ethyl methanesulfonate-induced chromosome breakage in the mouse

1968 • 117 citations

The effects of hydroxyurea and related compounds on the rat fetus.

1966 • 115 citations

The Chemical Production of Mutations

1967 • 111 citations

EFFECTS OF IONIZING RADIATIONS ON MAMMALIAN DEVELOPMENT.

1967 • 106 citations

Studies in Mammalian Radiation Genetics

1965 • 103 citations

Embryopathic Activity of Drugs.

1966 • 100 citations

Differentiation and the reaction of rat embryos to radiation

1954 • 98 citations

A preliminary report on hydrocephalus, spina bifida and other congenital anomalies in the rat produced by trypan blue; the significance of these results in the interpretation of congenital malformations following maternal rubella.

1948 • 97 citations

Teratogenic Response by Hamsters, Rats and Mice to Aflatoxin B1

1967 • 95 citations

Skeletal abnormalities in the offspring of rats reared on deficient diets

1941 • 93 citations

Some effects of nitrogen mustard on the development of external body form in the fetal rat

1948 • 93 citations

THE INDUCTION BY X-RAYS OF HEREDITARY CHANGES IN MICE

1935 • 91 citations

THE COMPARATIVE EFFECTS OF FIVE POLYFUNCTIONAL ALKYLATING AGENTS ON THE RAT FETUS, WITH ADDITIONAL NOTES ON THE CHICK EMBRYO

1958 • 91 citations

The induction of dominant lethal mutations in rats and mice with triethylenemelamine (TEM)

1960 • 90 citations

Congenital malformations in inbred strains of mice induced by riboflavin-deficient, galactoflavin containing diets

1957 • 89 citations

THE EFFECTS OF ALKYLATING AGENTS ON FERTILITY

1964 • 87 citations

Teratogenic effects of diphenylhydantoin sodium.

1966 • 84 citations

Some further observations on the sex ratio among infants born to survivors of the atomic bombings of Hiroshima and Nagasaki.

1966 • 79 citations

COMPARISON OF TERATOGENIC CHEMICALS IN THE RAT AND CHICK EMBRYOS

1957 • 75 citations

TERATOGENIC INTERACTION OF CHEMICAL AGENTS IN THE RAT

1964 • 75 citations

Chemically induced mutations in mice

1966 • 75 citations

The Genetic and Phenotypic Characteristics of Radiation-Induced Mutations in Mice

1959 • 75 citations

The production of congenital defects in the offspring of female mice treated with cortisone. A preliminary report.

1950 • 74 citations

A translocation in the house mouse and its effect on development

1934 • 73 citations

Effect of 4-Amino-Pteroylglutamic Acid (Aminopterin) on Early Pregnancy.

1950 • 73 citations

LIMITS OF TOXIC AND TERATOGENIC TOLERANCE OF DIMETHYL SULFOXIDE

1967 • 73 citations

Developmental Anomalies in Offspring of Pregnant Mice Treated with Nicotine

1958 • 72 citations

Drugs as Teratogens in Animals and Man

1965 • 72 citations

AN ANALYSIS OF TRANSLOCATIONS IN THE MOUSE

1946 • 71 citations

Strain and sex variations in the sensitivity of mice to dominant-lethal induction with ethyl methanesulfonate

1969 • 71 citations

Testing Chemicals for Mutagenicity in a Mammal

1966 • 69 citations

The Action of Various Agents upon the Rabbit Embryo

1961 • 64 citations

X‐ray sterility in the male house mouse

1933 • 63 citations

Effect of phenobarbital and SKF 525‐A on the teratogenicity of cyclophosphamide in mice

1968 • 63 citations

Effect of Azaserine and other growth-inhibiting agents on fetal development of the rat

1956 • 62 citations

Induction of Translocations in Mice by Triethylenemelamine

1957 • 60 citations

CHEMICAL INDUCTION OF DOMINANT LETHALS IN FEMALE MICE

1969 • 60 citations

TERATOGENICITY OF CAFFEINE IN MICE RELATED TO ITS MODE OF ADMINISTRATION

1969 • 59 citations

EFFECT OF BUSULPHAN ON THE DEVELOPING GONAD OF THE MALE RAT

1963 • 59 citations

The induction of dominant lethal mutations in rats by alkane sulphonic esters

1963 • 59 citations

Dominant lethal mutations induced in male mice by methyl methanesulphonate

1964 • 59 citations

The embryocidal and teratogenic effects of 5-bromodeoxyuridine in the pregnant hamster.

1965 • 58 citations

Mutagenicity tests in mice

1968 • 57 citations

THE EFFECT OF ALKYLATING AGENTS ON MALE RAT FERTILITY

1959 • 57 citations

Chlorambucil‐induced abnormalities of the urogenital system of rat fetuses

1961 • 56 citations

EFFECT OF BUSULPHAN ON THE DEVELOPING OVARY IN THE RAT

1963 • 56 citations

Die mutagene Wirkung von Endoxan bei der Maus

1966 • 55 citations

PRELIMINARY SURVEY OF HYDROXYUREA (NSC-32065) AS A TERATOGEN.

1964 • 55 citations

Colchicine‐induced heteroploidy in the mouse. I. The induction of triploidy by treatment of the gametes

1958 • 54 citations

A test for mutagenicity of caffeine in mice

1962 • 51 citations

GENETIC EFFECTS OF RADIATION ON MAMMALIAN POPULATIONS

1968 • 50 citations

�ber den Einflu� von Trenimon und Endoxan auf die Meiose der m�nnlichen Maus

1966 • 50 citations

THE ACTION OF TRIETHYLENEMELAMINE ON THE FERTILITY OF MALE RATS

1957 • 49 citations

The sensitivity of the mouse testis to the mutagenic action of triethylenemelamine

1959 • 49 citations

Polydactylism in the Offspring of Mice Injected with 5-Bromodeoxyuridine

1964 • 49 citations

Absence of teratogenic effect of butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) in rats and mice

1965 • 48 citations

Some effects of ionizing radiation and metabolic inhibition on the developing mammalian nervous system

1952 • 47 citations

�ber den Einflu� von Trenimon und Endoxan auf die Meiose der m�nnlichen Maus

1966 • 45 citations

Genetical effects of nitrogen mustard in the house mouse

1952 • 44 citations

Nitrogen Mustard as a Teratogenic Agent in the Mouse.

1954 • 43 citations

SEGMENTAL INTERCHANGE IN MICE

1944 • 43 citations

THE ACTION OF SOME NUCLEOTOXIC SUBSTANCES ON PREGNANCY

1956 • 43 citations

An investigation of the teratogenic potential of captan, folpet, and Difolatan

1968 • 42 citations

Die mutagene Wirkung von Trenimon bei der m�nnlichen Maus

1965 • 41 citations

Effect of feeding benzpyrene on reproduction in the rat

1964 • 41 citations

Mutationen durch chemische Einwirkung bei Säuger und Mensch

1967 • 41 citations

Antifertility Action and Metabolism of Trimethylphosphate in Rodents

1968 • 38 citations

Die teratogene Wirkung von Cyclophosphamid während der embryonalen Entwicklungsphase bei der Ratte

1965 • 38 citations

Induction of paternal sex-chromosome losses and deletions and of autosomal gene mutations by the treatment of mouse post-meiotic germ cells with triethylenemelamine

1967 • 37 citations

Colchicine Teratogenesis in Hamster Embryos.

1963 • 37 citations

Teratogenic effects in rats of growth inhibiting chemicals, including studies on thalidomide.

1962 • 37 citations

Compounds Interfering with Ovum Implantation and Development

1967 • 36 citations

Genetical effects of caffeine in mice

1962 • 36 citations

IV.—The Effects of Triethylenemelamine on the Fertility of Male Mice

1958 • 35 citations

The rapid detection of teratogenic activity.

1965 • 35 citations

TERATOGENICITY OF LITHIUM IN MICE

1969 • 35 citations

Effect of 2,4,6, Triamino-"S"-Triazine (TR), 2,4,6 "Tris" (Ethyleneimino)-"S"-Triazine (TEM) and N, N', N''-Triethylenephosphoramide (TEPA) on Rat Litter in Utero.

1957 • 34 citations

Congenital malformations induced by dimethyl sulphoxide in the golden hamster

1966 • 33 citations

A RADIOMIMETIC EFFECT OF TRIETHYLENEMELAMINE ON REPRODUCTION IN THE MALE RAT¹²³

1959 • 32 citations

Embryo Resorption and Placental Scar Formation in the Rat

1955 • 32 citations

Embryotoxic activity of some pesticides and drugs related to phthalimide

1965 • 31 citations

Chromosome changes in embryos treated with various teratogens

1967 • 31 citations

Experimenteller Beitrag zur Pr�fung teratogener Wirkungen von Arzneimitteln an der Laboratoriumsratte

1964 • 30 citations

Chromosomal Anomalies in Embryos of Diabetic Mice

1968 • 30 citations

A specific transplacental effect of urethane in mice.

1950 • 29 citations

Effects of Mitomycin C Administered at Various Stages of Pregnancy upon Mouse Fetuses

1968 • 28 citations

A New Mutant in the Progeny of Mice Treated with Nitrogen Mustard

1949 • 28 citations

Chromosome Breakage and Sterility in the Mouse

1941 • 27 citations

Induction by Roentgen Rays of Hereditary Changes in Mice

1941 • 27 citations

Chromosome Damage Induced by 5-Fluoro-2′ -Deoxyuridine in Relation to the Cell Cycle of the Chinese Hamster<xref ref-type="fn" rid="FN2">2</xref>

1968 • 27 citations

Changing perspectives on the genetic effects of radiation

1964 • 27 citations

Changing Perspectives on the Genetic Effects of Radiation

2012 • 26 citations

Effect of Triethylene Melamine on the Fertility of Rats

1955 • 26 citations

Does caffeine induce dominant lethal mutations in mice?

1969 • 26 citations

Dominant lethals in young female mice

1967 • 25 citations

Mesodermal Alterations Induced by Dimethyl Sulfoxide.

1966 • 25 citations

�ber einen Geschlechtsunterschied in der mutagenen Wirkung von Trenimon bei der Maus

1966 • 24 citations

TERATOGENIC EFFECT OF DIMETHYL SULPHOXIDE

1966 • 24 citations

The comparison of teratogenic and carcinogenic effects of some carbamate compounds.

1967 • 24 citations

Book Review: Chemistry and Prevention of Congenital Anomalies

1964 • 24 citations

The Effect of Triethylene-melamine on the Fertility of Female Mice

1959 • 24 citations

The prenatal exposure of mice to urethan and the consequent development of tumors in various tissues.

1967 • 23 citations

Mutagenit�tsuntersuchungen mit Trypaflavin und Hexamethylentetramin am S�uger in vivo und in vitro

1967 • 23 citations

Cell proliferation in embryonic mouse neural tube following urethane exposure

1969 • 22 citations

Relationship of dosage and time of administration to teratogenic effects of thio-TEPA in mice

1968 • 21 citations

Teratogenesis in Inbred Strains of Mice

1966 • 21 citations

Chlorpromazine Effects on Pregnancy and Offspring in Mice.

1963 • 20 citations

Artificial Production of Monstrosities in the Rabbit

1944 • 20 citations

Effect of transplacental mitotic inhibitors on the fetal hamster eye

1964 • 20 citations

A search for dominant mutations in F1 progeny of male mice treated with trenimone (triethyleneiminobenzoquinone-1,4)

1969 • 20 citations

The Effect of Prenatally Administered Busulphan on Rat Gonads

1966 • 20 citations

The sterilizing, carcinogenic and teratogenic effects of metepa in rats.

1966 • 19 citations

Effects of x‐rays in an inbred strain of guinea‐pigs

1932 • 19 citations

The experimental induction of gynogenesis in the mouse. III. Treatment of sperm with trypaflavine, toluidine blue, or nitrogen mustard

1958 • 18 citations

EMBRYOPATHIES IN THE RAT DUE TO ALKANE SULPHONATES

1968 • 18 citations

Acquired Chromosomal Anomalies Induced in Mice by Injection of a Teratogen in Pregnancy

1963 • 18 citations

Fibrillation and Potassium Influx

1959 • 18 citations

DEVELOPMENTAL ABNORMALITIES OF SKELETAL SYSTEM INDUCED BY ETHYLURETHAN IN THE RAT

1966 • 17 citations

Effects of Maternal Intake of Nicotine on Fetal and Newborn Rats.

1964 • 17 citations

Effects of Aflatoxin on Reproduction in Swine

1967 • 17 citations

Exogene Bildungsfehler (?Mi�bildungen?) durch Lostinjektion bei der graviden Maus

1955 • 17 citations

[Chemical constitution and teratogenic effect in rats. I. Carbonic acid amides, carbonic acid hydrazides and hydroxamic acids].

1968 • 17 citations

Further Investigations on the Cytotoxic and Morphogenetic Effects of Some Nitrogen Mustard Derivatives

1961 • 16 citations

Action of Some Sympatholytic Agents on Pregnancy in the Rat

1959 • 16 citations

Developmental anomalies in the eye of the rat after various experimental procedures

1953 • 15 citations

Effect of N-Desacetyl Thio Colchicine (TG) and N-Desacetyl-Methyl-Colchicine (MC) on Rat Fetus and Litter in utero.

1958 • 15 citations

Ultrastructural changes in embryonic mouse neural tube cells after urethane exposure

1968 • 15 citations

The Teratogenic Effect of the Steroid Nucleus in the Rat

1964 • 14 citations

Chemistry and Prevention of Congenital Anomalies

1964 • 14 citations

Effect of Maternal Administration of Dimethyl Sulfoxide on the Development of Rat Fetuses

1967 • 14 citations

Action of Triethanomelamine (TEM) on Early and Later Stages of Mouse Embryos

1959 • 14 citations

[Comparative teratologic studies in mouse and rat].

1965 • 14 citations

Additional observations on the effects of busulfan on cataract formation, duration of anesthesia, and reproduction in rats

1967 • 13 citations

Zur Wirkung von Teratogenen auf frühe Stadien der vorgeburtlichen Entwicklung der Ratte

1965 • 13 citations

Preliminary Notes on the Teratogenic and Embryocidal Effects of Colchicine on Mouse Embryos

1966 • 12 citations

EFFECT OF ALKANE SULPHONIC ESTERS ON OVARIAN DEVELOPMENT AND FUNCTION IN THE RAT

1969 • 11 citations

[ON THE PRENATAL TOXICITY OF DIPHENYLPYRALINE 8-CHLOROTHEOPHYLLINATE WITH REFERENCE TO EXPERIENCES WITH THALIDOMIDE AND CAFFEINE].

1964 • 11 citations

Probable induction of congenital anomalies in a lamb by apholate.

1965 • 11 citations

[Teratogenic effect of griseofulvin-forte on rat fetus].

1969 • 11 citations

TERATOGENIC ACTIVITY OF HYDROXY UREA

1965 • 11 citations

Effect of a Folic Acid Antagonist, Aminopterin, on Fetal Development and Nucleic Acid Metabolism in the Rat

1964 • 11 citations

Anti-mesodermal Activity of a Nitrogen Mustard Derivative

1963 • 10 citations

Does nitrogen mustard affect the foetus directly or secondarily by its effect on the mother ?

1966 • 10 citations

Untersuchungen �ber die teratogene Wirkung von Hydroxyharnstoff w�hrend der fr�hen und embryonalen Entwicklung der Maus

1969 • 10 citations

[Stress as a teratogenic factor. Experimental animal studies on induction of cleft palate].

1969 • 10 citations

Vascular changes in the gonopodium of poeciliid fishes during the metamorphosis of the anal fin.

1947 • 10 citations

Colchicine-Induced Craniofacial Defects in the Mouse Embryo

1968 • 9 citations

The susceptibility of the offspring of alloxan-diabetic mice to a teratogen

1965 • 9 citations

Effects of Feeding Benzo[a]pyrene on Fertility, Embryos, and Young Mice2

1965 • 9 citations

Developmental anomalies in mouse embryos induced by triethylene melamine (TEM).

1961 • 9 citations

Teratogenic effects of aminopterin in sheep

1968 • 9 citations

PRODUCTION OF HERITABLE PARTIAL STERILITY IN THE MOUSE BY METHYL METHANESULPHONATE

1964 • 8 citations

Analysis of the Lethal Effect of ‘Myleran’ on Rat Embryos

1966 • 8 citations

Effect of Triethylenemelamine on Reproductive Capacity of Mouse Spermatozoa.

1960 • 8 citations

Congenital malformations in mice induced by nitrogen mustard.

1959 • 8 citations

[INDUCED EMBRYOPATHIES IN MAMMALS].

1964 • 8 citations

Effects of nitrogen mustard injections on the embryos of pregnant rats.

1950 • 7 citations

Is man a unique animal in response to drugs?

1969 • 7 citations

On the Effects of Oolchicine Treatment of Mouse Embryos

1947 • 6 citations

MATERNAL AND FOETAL RESPONSES TO CHRONIC STRESS IN PREGNANCY - A STUDY IN ALBINO RATS

1963 • 6 citations

Characteristics of the teratogenic effect of aminopterin compared with that of other teratogenic agents

1966 • 6 citations

[Chemically induced fetopathies in the rat. Experimental studies on the effect of cyclophosphamide and N-methyl-N-nitroso-urea after administration on day 15 or 16 of gestation].

1967 • 6 citations

Mitigated Teratogenicity of Thio-TEPA in Goldthioglucose Obese Mice.

1967 • 5 citations

The effects of some antimitotic compounds on pregnancy in the mouse.

1957 • 5 citations

Some Aspects of the Effect of Endoxan on Developing Mouse Embryos (With 3 Text-figures and 1 Table)

1965 • 4 citations

STRESS AND PREGNANCY

1956 • 4 citations

The teratogenicity of 5-bromodeoxyuridine in the pregnant Syrian hamster

1965 • 4 citations

The effect of nicotine on the female rabbit and developing foetus; an experimental study.

1951 • 4 citations

[Peculiarities of the pathogenic effect of sarcolysine on embryogenesis in rats].

1966 • 4 citations

Effects of myleran on the development of the skeletal system in the rat and mouse embryos.

1965 • 4 citations

THE PATHOGENIC ACTION OF MYELOSAN ON EMBRYOGENESIS

1964 • 3 citations

Effects of Ethyl Urethane on Reproduction in Mice

1952 • 3 citations

Transplacental effects of drugs in mice.

1965 • 3 citations

Effects of urethan on the teratogenic action of hypervitaminosis A.

1965 • 3 citations

Effects of chlorpromazine and psilocin on pregnancy of c57bl/10 mice and their offspring at birth. Abstr.

1967 • 3 citations

Effect of Maternal Nicotine Intake on Fetal Weight and Length in Rats.

1967 • 3 citations

Verschiedene Wirkmechanismen im teratologischen Experiment

1965 • 3 citations

[The peculiar features of the injuring effect of aminopterin at different stages of rat embryogenesis].

1965 • 3 citations

The effect of methylcholanthrene painting of the ovaries on the progeny of mice.

1959 • 3 citations

Does nitrogen mustard mimic the X-ray effects in any case?

1964 • 2 citations

[Fertilization and embryonic development in rabbits after affecting spermatozoa with chemical mutagens in vitro].

1968 • 2 citations

Colcemid-induced teratogenesis in hybrid mouse embryos. Abstr.

1966 • 2 citations

Lack of effect of nicotine on the fertility of male and female mice

1962 • 2 citations

Atomic bombs, inbreeding, and Japanese genes: the Russel Lecture for 1966.

1966 • 2 citations

The induction of dominant lethals in inbred mice by ethylene imine. (russ., Eng. Summ.).

1967 • 1 citations

[Postnatal fate of polydactyly induced by administration of ethylurethane to pregnant mice].

1966 • 1 citations

A search for urinary 4',10-dimethyl-1,2-benzanthracene and other hydrocarbons.

1967 • 1 citations

The influence of the drug Bayer E-39 solubile on the embryonic development of the rat.

1966 • 1 citations

Experimentally produced congenital anomalies through folio acid deficient diet.

1958 • 1 citations

MALDEVELOPMENT OF THE FETUS CAUSED BY NICOTINE ADMINISTRATION DURING PREGNANCY AND ITS RELATION TO MATERNAL AGE

1964 • 1 citations