The Characteristics Of Animal Cells Transformed In Vitro
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Abstract
References (205)
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1956 • 12,141 citations
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1965 • 5,595 citations
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1957 • 1,241 citations
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1953 • 686 citations
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1958 • 555 citations
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1968 • 547 citations
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1958 • 488 citations
Density Dependent Inhibition of Cell Growth in Culture
1967 • 440 citations
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1966 • 436 citations
Basis for the Acquisition of Malignant Potential by Mouse Cells Cultivated in vitro
1968 • 425 citations
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1958 • 402 citations
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1963 • 362 citations
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1968 • 336 citations
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1963 • 329 citations
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1958 • 329 citations
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1966 • 322 citations
A SPECIFIC COMPLEMENT-FIXING ANTIGEN PRESENT IN SV40 TUMOR AND TRANSFORMED CELLS
1963 • 320 citations
SV40‐induced transformation of human diploid cells: Crisis and recovery
1965 • 317 citations
INDUCTION OF CELLULAR DNA SYNTHESIS BY POLYOMA VIRUS
1965 • 304 citations
In Vitro Cell Transformation with Chemical Carcinogens
1963 • 304 citations
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1965 • 298 citations
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1960 • 250 citations
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1963 • 247 citations
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1963 • 243 citations
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1961 • 242 citations
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1961 • 241 citations
Transformation of Cultures of Human Tissue Infected with Simian Virus SV40
1962 • 237 citations
Quantitative studies on the malignant transformation of mouse prostate cells by carcinogenic hydrocarbons in vitro
1969 • 237 citations
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1964 • 236 citations
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1967 • 222 citations
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1958 • 220 citations
Transplantation of Polyoma Virus-induced Tumors in Mice
1961 • 199 citations
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1963 • 193 citations
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1960 • 187 citations
Studies on transformation of hamster cells by polyoma virus in vitro
1961 • 178 citations
Metabolic Controls in Cultured Mammalian Cells
1965 • 178 citations
ROLE OF CHROMOSOMES IN CANCEROGENESIS, AS STUDIED IN SERIAL TISSUE CULTURE OF MAMMALIAN CELLS
1958 • 176 citations
SPECIFIC COMPLEMENT-FIXING VIRAL ANTIGENS IN HAMSTER AND GUINEA PIG TUMORS INDUCED BY THE SCHMIDT-RUPPIN STRAIN OF AVIAN SARCOMA
1964 • 175 citations
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1966 • 175 citations
Studies on carcinogenesis by avian sarcoma viruses. VI. Differential multiplication of uninfected and of converted cells in response to insulin
1967 • 174 citations
Heritability of cellular differentiation: clonal growth and expression of differentiation in retinal pigment cells in vitro.
1966 • 167 citations
Chromosomal Evolution in Cell Populations
1962 • 157 citations
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1965 • 154 citations
Induction of cellular DNA synthesis by polyoma virus.
1965 • 146 citations
Multiplication and Cytopathogenicity of Simian Vacuolating Virus 40 in Cultures of Human Tissues.
1962 • 142 citations
Avian Tumor Viruses
1965 • 140 citations
Putrescine and related amines as growth factors for a mammalian cell line
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Requirements for Growth of Single Human Cells
1959 • 133 citations
Discrete foci of altered chicken embryo cells associated with Rous sarcoma virus in tissue culture
1956 • 131 citations
Reversion of Properties in Cells transformed by Polyoma Virus
1968 • 128 citations
A substance in conditioned medium which enhances the growth of small numbers of chick embryo cells
1966 • 127 citations
INDUCED MALIGNANCY IN CELLS FROM RAT MYOCARDIUM SUBJECTED TO INTERMITTENT ANAEROBIOSIS DURING LONG PROPAGATION IN VITRO
1953 • 127 citations
Two spontaneously transformed cell lines derived from the same hamster embryo culture
1967 • 126 citations
Effect of SV40 Virus Immunization on Growth of Transplantable SV40 and Polyoma Virus Tumors in Hamsters.
1963 • 125 citations
Specific complement-fixing antigens in polyoma tumors and transformed cells
1965 • 123 citations
The interaction of 7,12-dimethylbenz(a)anthracene with cells sensitive and resistant to toxicity induced by this carcinogen.
1967 • 121 citations
New Surface Antigen in Cells Transformed by Simian Papovavirus SV40.
1965 • 117 citations
Cell susceptibility to transformation and cytotoxicity by the carcinogenic hydrocarbon benzo[a]pyrene.
1966 • 116 citations
Rapid transformation of human fibroblasts with low growth potential into established cell lines by SV40
1963 • 112 citations
Studies of Carcinogenesis by Avian Sarcoma Viruses
1966 • 111 citations
Reversion in Hamster Cells Transformed by Rous Sarcoma Virus
1965 • 110 citations
In Vitro Transformation of Normal Cells by Polyoma Virus
1961 • 106 citations
The Oncogenic DNA Viruses: A Review of In Vitro Transformation Studies
1968 • 105 citations
TISSUE CULTURE POPULATIONS AND THEIR RELATION TO THE TISSUE OF ORIGIN
1960 • 103 citations
On the mechanism of polyoma virus-induced synthesis of cellular DNA.
1965 • 103 citations
Surface mucopolysaccharides of polyoma virus transformed cells
1963 • 102 citations
The production of hyaluronate by spontaneously established cell lines and viral transformed lines of fibroblastic origin
1965 • 101 citations
Transformation of Bovine Tissue Culture Cells by Bovine Papilloma Virus
1963 • 100 citations
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1966 • 100 citations
Production of Malignancy in Vitro. V. Results of Injections of Cultures into Mice
1943 • 98 citations
Selection of Morphologically Normal Cell Lines from Polyoma-transformed BHK21/13 Hamster Fibroblasts
1968 • 97 citations
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1964 • 93 citations
Properties of Syrian hamster cells transformed in the presence of carcinogenic hydrocarbons
1967 • 91 citations
Loss of T-antigen from somatic hybrids between mouse cells and SV40-transformed human cells.
1968 • 90 citations
Malignant Transformation of Cells in Vitro
1965 • 89 citations
Cell susceptibility to transformation by x-irradiation and fixation of the transformed state.
1967 • 88 citations
THE DEVELOPMENT OF SOMATIC MUTATIONS IN MICE WITH AGE
1963 • 88 citations
In vitro Transformation of Hamster Kidney Cells by Human Adenovirus Type 12.
1964 • 86 citations
Electrophoretic Investigations of a Clone of Hamster Fibroblasts and Polyoma-Transformed Cells from the Same Population
1962 • 85 citations
Transformation of mouse cell line 3T3 by SV40: Dose response relationship and correlation with SV40 tumor antigen production
1966 • 83 citations
Some Properties of Bovine Papilloma Virus
1964 • 82 citations
Microelectrophoresis of Normal and Transformed Clones of Hamster Kidney Fibroblasts
1964 • 80 citations
Malignant Transformation in vitro by Carcinogenic Hydrocarbons
1967 • 78 citations
SIGNIFICANCE OF CONTINUED VIRUS PRODUCTION IN TISSUE CULTURES RENDERED NEOPLASTIC BY POLYOMA VIRUS
1960 • 77 citations
Antigenic Properties of Other Experimental Tumors
1962 • 76 citations
A DIFFUSIBLE FACTOR WHICH SUSTAINS CONTACT INHIBITION OF REPLICATION
1969 • 76 citations
CELLULAR ALTERATIONS IN THE MCH LINE OF CHINESE HAMSTER CELLS FOLLOWING INFECTION WITH HERPES SIMPLEX VIRUS
1963 • 75 citations
Albumin Replacement by Fatty Acids in Clonal Growth of Mammalian Cells
1963 • 75 citations
RAPID TRANSFORMATION OF HUMAN FIBROBLAST CULTURES BY SIMIAN VIRUS 40
1963 • 75 citations
Induction of Malignancy in vitro in Newborn Hamster Kidney Tissue Infected with Simian Vacuolating Virus (SV40)
1962 • 74 citations
Infection of chick iris epithelium with the Rous sarcoma virus in vitro
1960 • 73 citations
SV-40 Induced Proliferation of Tissue Culture Cells of Rabbit, Mouse, and Porcine Origin
1963 • 72 citations
Transformation of hamster embryo cells in vitro by polyoma virus: Morphological, karyological, immunological and transplantation characteristics
1965 • 71 citations
The synthesis of homocystine, cystathionine, and cystine by cultured diploid and heteroploid human cells.
1966 • 71 citations
Chapter 4: Contact and Short-Range Interactions Affecting Growth of Animal Cells in Culture
1967 • 71 citations
The suppression of morphological alterations in cells infected with Rous sarcoma virus
1960 • 70 citations
Parallel orientation of fibroblasts in vitro
1968 • 68 citations
Maintenance of Normal in situ Chromosomal Features in Long-Term Tissue Cultures
1961 • 63 citations
The inhibition of chick embryo cell growth by medium obtained from cultures of Rous sarcoma cells
1966 • 62 citations
Chromosome variation in cell populations derived from pig kidney.
1961 • 62 citations
National Academy of Sciences: Abstracts of Papers Presented at the Autumn Meeting, 14-16 November 1960, Philadelphia, Pennsylvania
1960 • 62 citations
Studies on carcinogenesis by avian sarcoma viruses: VIII. Glycolysis and cell multiplication
1968 • 61 citations
Biochemically marked variants of the syrian hamster fibroblast cell line BHK21 and its derivatives
1965 • 61 citations
Serum Albumin Supplemented Medium for Long Term Cultivation of Mammalian Fibroblast Strains.
1964 • 61 citations
Properties of clonal lines of murine sarcoma virus transformed cells
1969 • 60 citations
Diphenamid Metabolism in Plants
1967 • 59 citations
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1956 • 57 citations
Growth Inhibitor of Hamster Fibroblast Cells
1966 • 57 citations
Transformation of a Hamster Cell Line by Adenovirus Type 12
1968 • 57 citations
The effect of carcinogenic hydrocarbons on rodent and primate cells in vitro
1965 • 56 citations
An association between viral transformation and forssman antigen detected by immune adherence in cultured BHK21 cells
1968 • 56 citations
Malignant conversion of cells in vitro by carcinogens and viruses.
1966 • 49 citations
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1950 • 49 citations
The basis of the tumorigenicity of BHK 21 cells
1968 • 49 citations
COMPARATIVE STUDIES IN ROUS SARCOMA WITH VIRUS, TUMOR CELLS, AND CHICK EMBRYO CELLS TRANSFORMED IN VITRO BY VIRUS
1961 • 48 citations
Studies on the transformation of hamster embryo cells in culture by polyoma virus
1963 • 47 citations
Clonal growth of primary human cell cultures
1964 • 46 citations
Temperature sensitivity of polyoma virus, induction of cellular DNA synthesis, and multiplication of transformed cells at high temperature.
1967 • 46 citations
GROWTH OF HUMAN TUMOR CELLS IN SUSPENSION CULTURES.
1963 • 45 citations
Transformation in vitro of Mammalian Cells by Polyoma and Simian 40 Viruses*
2015 • 44 citations
Microbiological Aspects of Tissue Culture
1959 • 43 citations
A comparative study of respiratory metabolism in cultured mammalian cell strains
1963 • 42 citations
Changes in Surface Antigens of SV40-Virus Transformed Cells
1969 • 42 citations
Malignant Transformation <italic>In Vitro</italic> of Cells From C57BL Mouse Normal Pulmonary Tissue
1963 • 41 citations
Effect of Serum on Spontaneous Neoplastic Transformations <italic>In Vitro</italic>
1966 • 41 citations
Transformation of bovine cells in vitro after inoculation of simian virus 40 or its nucleic acid
1965 • 39 citations
Cobalt-tolerance and mucopolysaccharide production in rat dermal fibroblasts in culture
1961 • 38 citations
Limited Growth Period of Human Lung Cell Lines Transformed by Simian Virus 40
1964 • 38 citations
TRANSFORMATION INDUCED BY SIMIAN VIRUS 40 IN NEWBORN SYRIAN HAMSTER RENAL CELL CULTURES
1963 • 38 citations
Antiviral and Antitumor Immunologic Mechanisms Operative in the Shope Papilloma-Carcinoma System
1962 • 38 citations
Studies on culture lines derived from mouse liver parenchymatous cells grown in long-term tissue culture.
1958 • 37 citations
Differential Toxicity Response of Normal and Neoplastic Cells In Vitro to 3,4-Benzopyrene and 3-Methylcholanthrene
1964 • 36 citations
Reversion in Polyoma-transformed Cells: Retransformation, Induced Antigens and Tumorigenicity
1969 • 36 citations
Presence of avian tumor virus group-specific antigen in nonproducing Rous sarcoma cells of the chicken
1965 • 34 citations
OBSERVATIONS ON THE CONVERSION OF NORMAL INTO MALIGNANT CELLS
1945 • 34 citations
ISOMORPHIC SEX CHROMOSOMES, AUTOSOMAL HETEROMORPHISM, AND TELOMERIC ASSOCIATIONS IN THE GREY HAMSTER OF ARMENIA, CRICETULUS MIGRATORIUS, PALL
2009 • 34 citations
Studies on the lytic interaction and cell transformation with a large- and a small-plaque mutant of polyoma virus
1963 • 33 citations
Quantitative growth studies with chick myoblasts in glass substrate cultures.
1957 • 33 citations
Comparative Chromosomal Study of 31 Cultured Mammalian Cell Lines<xref ref-type="fn" rid="fn1">2</xref>
1962 • 31 citations
Single-cell platings from freshly isolated mammalian tissue
1961 • 31 citations
Further Studies on SV40-Induced Transformation in Human Renal Cell Cultures. I. Eventual Failure of Subcultivation Despite a Continuing High Rate of Cell Division.
1964 • 30 citations
Effect of heterologous antilymphoid-cell serum on tumor isografts and viral leukemogenesis.
1967 • 30 citations
Studies on transformation of Syrian hamster cells by simian virus 40 (SV40): acquisition of oncogenicity by virus-exposed cells apparently unassociated with the viral genome.
1965 • 29 citations
GROWTH PROPERTIES OF POLYOMA VIRUS-INDUCED HAMSTER TUMOR CELLS.
1963 • 28 citations
Stimulation of DNA Synthesis in Human and Hamster Cells by Human Adenovirus Types 12 and 5.
1966 • 27 citations
SPECIFIC TRANSPLANTATION IMMUNITY IN RELATION TO ROUS SARCOMA VIRUS TUMORIGENESIS IN MICE
1966 • 27 citations
Demonstration of common specific antigen(s) in mouse and hamster polyoma tumors
1966 • 26 citations
A Persistent Strain of Diploid Fibroblasts<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>
1964 • 25 citations
Development and Characteristics of the Rabbit Kidney Cell Strain, LLC-RK1
1965 • 24 citations
Attempts to produce carcinogenesis in organ cultures of mouse prostate with polycyclic hydrocarbons
1967 • 24 citations
The karyotypes of cell lines recently established from normal mouse tissues
1959 • 23 citations
Chromosome Number and Morphology of a Human Preinvasive Neoplasm
1964 • 22 citations
Chromosome constancy in the corneal epithelium of the mouse
1956 • 22 citations
Long-term cultivation of diploid rat cells
1964 • 22 citations
Growth and genetics of somatic mammalian cellsin vitro
1958 • 22 citations
LONG-TERM CULTIVATION OF HUMAN AND BOVINE FIBROBLASTIC CELLS MORPHOLOGICALLY TRANSFORMED IN VITRO BY ROUS SARCOMA VIRUS
1966 • 21 citations
PROLONGED CULTURE OF DIPLOID HUMAN CELLS.
1964 • 20 citations
Glycolysis and Respiration of Transformed BHκ2I Cells
1964 • 20 citations
Chromosome Analysis of Three Virus-Associated Chicken Tumors: Rous Sarcoma, Erythroleukemia, and RPL12 Lymphoid Tumor<xref ref-type="fn" rid="FN1">2</xref>
1963 • 20 citations
Clonal studies on normal cells and on their neoplastic transformation in vitro.
1958 • 20 citations
THE AMINO ACID REQUIREMENTS OF RABBIT FIBROBLASTS, STRAIN RM3-56
1957 • 20 citations
Serial culture of Syrian hamster fibroblasts in albumin fortified medium and their regular development into established lines
1968 • 19 citations
Chromosomal Variability in Clonal Populations of a Chinese Hamster Cell Strain
1964 • 19 citations
Action of 7,12-Dimethylbenz(Alpha)Anthracene on the Mitotic Activity of Normal and Malignant Rat Fibroblasts in vitro
1962 • 18 citations
Isolation and long-term culture of diploid mammalian cell lines.
1962 • 17 citations
Comparative Studies in Rous Sarcoma. IV. Glucose Metabolism of Normal and Rous Sarcoma Virus-Infected Cells.
1963 • 17 citations
Homologous Transfer of Rous Sarcoma by Cells<xref ref-type="fn" rid="fn1">2</xref>
1962 • 17 citations
The culture of embryonic chicken heart cells
1965 • 16 citations
CYTOLOGICAL ABERRATIONS IN CULTURES OF "NORMAL" MONKEY KIDNEY EPITHELIAL CELLS
1958 • 16 citations
Influence of Animal Passage on a Line of Tissue-Culture Cells
1959 • 15 citations
COMPARATIVE STUDIES IN ROUS SARCOMA WITH VIRUS, TUMOR CELLS AND CHICK EMBRYO CELLS TRANSFORMED IN VITRO BY VIRUS
1962 • 14 citations
An Epithelioid Variant of the BHK21 Hamster Fibroblast Line and Its Transformation by Polyoma Virus<xref ref-type="fn" rid="FN1">2</xref>
1966 • 14 citations
The development of resistance to carcinogen-induced cytotoxicity in hamster embryo cultures
1968 • 14 citations
Characteristics of the Syrian Hamster Ribonucleic Acid Present in Cells Transformed by Polyoma, Simian Virus 40, or Adenovirus 12
1969 • 12 citations
The morphology and transplantability of mofse embryo cells transformed in vitro by polyoma virus
1964 • 10 citations
Report on the workshop on virus induction by cell association
1968 • 9 citations
Rous sarcoma virus production from clones of nontransformed chick embryo fibroblasts
1966 • 9 citations
Malignant Transformation and Chromosome Change of Two Cell Lines from Syrian Hamster Embryonic Tissue <i>in vitro</i>
1966 • 9 citations
Effect of horse serum and fetal calf serum on stability of chromosomes in mouse embryo cells in vitro.
1967 • 8 citations
Establishment of Two Cell Lines from Syrian Hamster Embryonic Tissue <i>in vitro</i>
1965 • 8 citations
Further studies on radiation-induced sensitivity of hamster cells to transformation by polyoma virus
1964 • 8 citations
Triploidy in a Human Cell Line
1965 • 8 citations
Morphological Transformation in an Established Line of Pig Kidney Cells.
1962 • 8 citations
Observations during in vitro growth of cells derived from rabbit kidney
1961 • 7 citations
Production of Malignancy <italic>in vitro</italic>. IX. Description of Cells at the Fluid Interface of the Culture<xref ref-type="fn" rid="fn1">2</xref>
1950 • 7 citations
RECENT ADVANCES IN THE STUDY OF VIRAL ONCOGENESIS
1967 • 5 citations
Formation of tumor colonies in the lungs of rats injected with rat embryo cells immediately after infection of the cells with polyoma virus
1965 • 4 citations
Absence of Malignant Transformation After Weekly Irradiation of a Mouse Spleen Cell Culture
1966 • 3 citations
Routine Development of Permanent Strains of Fibroblasts from Bone Marrow of Adult Rabbits
1960 • 2 citations
Deleted Work
1955 • 0 citations