Quaternary derivatives of narcotic antagonists: Stereochemical requirements at the chiral nitrogen for and activity

KINETIC PARAMETERS OF NARCOTIC AGONISTS AND ANTAGONISTS, WITH PARTICULAR REFERENCE TO N‐ALLYLNOROXYMORPHONE (NALOXONE)

1968 • 392 citations

In Vitro Models in the Study of Structure-Activity Relationships of Narcotic Analgesics

1975 • 289 citations

Further properties of stereospecific opiate binding sites in rat brain: on the nature of the sodium effect.

1975 • 186 citations

Quaternary narcotic antagonists' relative ability to prevent antinociception and gastrointestinal transit inhibition in morphine-treated rats as an index of peripheral selectivity

1982 • 89 citations

Effects of naloxone and its quarternary analogue on stimulation-induced feeding

1983 • 58 citations

N-methylnalorphine: definition of N-allyl conformation for antagonism at the opiate receptor

1982 • 16 citations

Pharmacological actions of levallorphan allyl bromide (CM 32191), a new peripheral narcotic antagonist

1982 • 14 citations