Cytogenetics of Aging

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

1961 • 3,881 citations

New Technique for Distinguishing between Human Chromosomes

1971 • 1,168 citations

Chromosomal Localization of Mouse Satellite DNA

1970 • 1,119 citations

THE CHROMOSOME NUMBER OF MAN

2010 • 1,059 citations

Identification of human chromosomes by DNA-binding fluorescent agents

1970 • 989 citations

Localization of heterochromatin in human chromosomes

1971 • 965 citations

Microfluorometric Detection of Deoxyribonucleic Acid Replication in Human Metaphase Chromosomes

1973 • 838 citations

[Study of somatic chromosomes from 9 mongoloid children].

1959 • 809 citations

Zur Frage der Entstehung maligner Tumoren

1914 • 796 citations

High Resolution of Human Chromosomes

1976 • 786 citations

Mendelian Inheritance in Man

1998 • 760 citations

MULTIPLE CONGENITAL ANOMALY CAUSED BY AN EXTRA AUTOSOME

1960 • 676 citations

A NEW TRISOMIC SYNDROME

1960 • 610 citations

Characteristics of a Human Diploid Cell Designated MRC-5

1970 • 593 citations

The relationship between in vitro cellular aging and in vivo human age.

1976 • 559 citations

THE NORMAL HUMAN FEMALE AS A MOSAIC OF X-CHROMOSOME ACTIVITY: STUDIES USING THE GENE FOR G-6-PD-DEFICIENCY AS A MARKER

1962 • 503 citations

Chromosomes and Cancer.

1975 • 437 citations

OBSTETRIC DELIVERY TODAY

1976 • 419 citations

Ageing of Clones of Mammalian Cells

1973 • 409 citations

Altered Enzymes in Ageing Human Fibroblasts

1972 • 408 citations

Sur une nouvelle technique d'analyse du caryotype humain.

1971 • 382 citations

Change of Human Chromosome Count Distributions with Age: Evidence for a Sex Difference

1963 • 273 citations

Fanconi's Anaemia in the Genetics of Neoplasia

1971 • 263 citations

Age-associated aneuploidy: Loss of Y chromosome from human bone marrow cells with aging

1972 • 258 citations

Distribution of Human Chromosome Counts in Relation to Age

1961 • 242 citations

Transformation of Cultures of Human Tissue Infected with Simian Virus SV₄₀

1962 • 237 citations

The utilization of bromodeoxyuridine incorporation into DNA for the analysis of cellular kinetics

1976 • 216 citations

NEOPLASIA AND DOWNS SYNDROME

1970 • 200 citations

CELL SIZE, NUCLEAR CONTENT, AND THE DEVELOPMENT OF POLYPLOIDY IN THE MAMMALIAN LIVER

1967 • 197 citations

ANEUPLOIDY IN THE DEGENERATIVE PHASE OF SERIAL CULTIVATION OF HUMAN CELL STRAINS

1963 • 193 citations

Chromosome measurement and sorting by flow systems.

1975 • 190 citations

Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos.

1976 • 166 citations

Human Chromosome 21 Dosage: Effect on the Expression of the Interferon Induced Antiviral State

1974 • 143 citations

Chromosomal Breakage and Acute Leukemia in Congenital Telangiectatic Erythema and Stunted Growth

1966 • 129 citations

CULTURE CHARACTERISTICS OF HUMAN FIBROBLASTS PROPAGATED SERIALLY

1957 • 125 citations

Chromosome studies on adults

1966 • 123 citations

Non‐random chromosomal aberrations in SV₄₀‐transformed human cells

1963 • 115 citations

Replication Rate and Lifespan of Cultured Fibroblasts in Down's Syndrome

1972 • 101 citations

Premature centromere division: A mechanism of non‐disjunction causing X chromosome aneuploidy in somatic cells of man

1975 • 94 citations

Chromosome changes during the in vitro ageing of MRC-5 human fibroblasts

1975 • 77 citations

Chromosome Investigations of a Small Isolated Human Population: Chromosome Abnormalities and Distribution of Chromosome Counts According to Age and Sex Among the Population of Tristan Da Cunha

1965 • 76 citations

Cytological Studies of Tumors. XL. Chromosome Studies in Fifty-Two Human Tumors<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1964 • 72 citations

Chromosome Loss compared with Chromosome Size, Age and Sex of Subjects

1970 • 57 citations

Chronology and Pattern of Human Chromosome Replication

1967 • 56 citations

HUMAN CHROMOSOME ANALYSIS BY COMPUTER—AN OPTICAL PATTERN RECOGNITION PROBLEM*

1966 • 52 citations

KLINEFELTER'S SYNDROME, A CLINICAL AND CYTOGENIC STUDY IN TWENTY-FOUR CASES

1967 • 50 citations

Chromosomes in Senile Dementia

1968 • 48 citations

45,X cell lines in adult men: loss of Y chromosome, a normal aging phenomenon?

1971 • 47 citations

Aneuploidy and age in a population survey.

1967 • 46 citations

Chromosomes in old age: A six year longitudinal study

1976 • 44 citations

Senescence and human chromosome changes

1975 • 41 citations

Chromosome examinations in aged twins.

1970 • 40 citations

Effect of temperature on the longevity of human fibroblasts in culture

1973 • 40 citations

Automatic karyotyping of quinacrine mustard stained human chromosomes

1971 • 39 citations

Chromosomes in Senile, Presenile, and Arteriosclerotic Dementia

1970 • 34 citations

Chromosomal Altertions in Three Age Groups of Human Females

1969 • 33 citations

Stroop Color-Word Test, Non-Psychotic Organic Brain Syndrome, and Chromosome Loss in Aged Twins

1971 • 32 citations

Chromosome aberrations and culture time

1969 • 28 citations

In vitro cultivation of cells from aneuploid human embryos. Initiation of cell lines and longevity of the cultures

1975 • 26 citations

Variation in the Human Chromosome Number

1967 • 25 citations

Age And Polyploidy Of Rat Liver NUCLEI As Measured By Volume And DNA Content

1959 • 25 citations

Chronology and pattern of human chromosome replication

1968 • 25 citations

Rate of Chromosome Duplication at the End of the Deoxyribonucleic Acid Synthetic Period in Human Blood Cells

1965 • 23 citations

Age and Chromosomes

1966 • 20 citations

Chromosome Changes Revealed by the Q-Band Staining Method during Cell Senescence of WI-38

1974 • 19 citations

Effects of Age and Radiation Exposure on Chromosomes in a Marshall Island Population

1972 • 16 citations

A study of the cytogenetics of the human cell strain WI-38

1973 • 14 citations

Chromosomes and Mental Changes in Octogenarians Preliminary Findings

1969 • 12 citations

Chromosomal Abnormalities in Spleens of New Zealand Black Mice, A Strain Characterized by Autoimmunity and Malignancy

1973 • 11 citations

Molecular and cellular mechanisms of aging

2002 • 9 citations

Age and Chromosomes

1966 • 7 citations

Aging and X chromosome loss in the human ovary.

1975 • 4 citations

Chromosome Aberrations in Leucocytes of Normal Human Adults from 49 Couples

1971 • 3 citations