Heterogeneity of Peptide Hormones

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

1966 • 2,239 citations

Radioimmunoassay of gastrin

1970 • 805 citations

Insulin Biosynthesis: Evidence for a Precursor

1967 • 699 citations

Immunochemical Heterogeneity of Parathyroid Hormone in Plasma

1968 • 369 citations

Ectopic ACTH Production in Carcinoma of the Lung

1974 • 270 citations

An Improved Technique for the Preparation of Isolated Rat Adrenal Cells: A Sensitive, Accurate and Specific Method for the Assay of ACTH

1971 • 263 citations

Heterogeneity of Parathyroid Hormone. CLINICAL AND PHYSIOLOGIC IMPLICATIONS

1973 • 223 citations

ISOLATION OF TWO " BIG GASTRINS " FROM ZOLLINGER-ELLISON TUMOUR TISSUE

1972 • 213 citations

Size and Charge Distinctions Between Endogenous Human Plasma Gastrin in Peripheral Blood and Heptadecapeptide Gastrins

1970 • 208 citations

Size heterogeneity of immunoreactive human ACTH in plasma and in extracts of pituitary glands and ACTH-producing thymoma

1971 • 186 citations

Nature of Immunoreactive Gastrin Extracted from Tissues of Gastrointestinal Tract

1971 • 168 citations

Proparathyroid Hormone: Identification of a Biosynthetic Precursor to Parathyroid Hormone

1972 • 162 citations

Parathyroid Hormone: Secretion and Metabolism In Vivo

1971 • 156 citations

Multiple Immunoreactive Molecular Forms of Parathyroid Hormone in Human Serum

1972 • 155 citations

"Big insulin": a new component of plasma insulin detected by immunoassay.

1968 • 152 citations

Further Studies on the Nature of Immunoreactive Gastrin in Human Plasma

1971 • 138 citations

Characteristics of “Big ACTH” in Human Plasma and Pituitary Extracts

1973 • 132 citations

And now, “big, big” gastrin

1972 • 131 citations

Calcemic Fraction-A: Biosynthetic Peptide Precursor of Parathyroid Hormone

1972 • 123 citations

Evidence for “Big” and “Little” Components of Human Plasma and Pituitary Growth Hormone

1973 • 117 citations

EVIDENCE FOR PROINSULIN IN HUMAN URINE AND SERUM

1968 • 114 citations

Insulin in blood and insulin antibodies

1966 • 113 citations

Existence of Two Forms of Immunoreactive Growth Hormone in Human Plasma*

1972 • 110 citations

Additional Studies on the Nature of Big Big Gastrin

1973 • 106 citations

Big ACTH: Conversion to Biologically Active ACTH by Trypsin

1974 • 106 citations

Human parathyroid hormone: Glandular and secreted molecular species

1971 • 91 citations

Biosynthesis of Human Growth Hormone and Prolactin

1970 • 83 citations

Native Human Parathyroid Hormone: an Immunochemical Investigation

1970 • 69 citations

Synthesis and secretion of parathyroid hormone in vitro

1971 • 68 citations

Significance of Human Plasma Insulin Sephadex Fractions

1969 • 66 citations

Plasma Biological and Immunore active Human Growth Hormone-like Activity¹

1970 • 50 citations

Circulating Insulins

1969 • 44 citations

Characterization of Growth Hormone of Different Molecular Weights in Rat, Dog and Human Pituitaries

1972 • 44 citations

State of Human Growth Hormone in Plasma and Changes in Stored Solutions of Pituitary Growth Hormone

1966 • 31 citations

Peptide hormones in plasma.

1966 • 30 citations

Circulating insulin: the proinsulin-like properties of “big” insulin in patients without islet cell tumors

1971 • 28 citations

“Big, big insulin”

1973 • 27 citations

"BIG GASTRINS " IN THE ZOLLINGER-ELLISON SYNDROME

1972 • 19 citations

Regulation of Aldosterone Production During Pregnancy in the Rat1

1973 • 17 citations

Human parathyroid gland immunoreactive peptides--evidence for proparathormone.

1971 • 7 citations