Human Tumour Xenograft Models for Use with an In Vitro-Based, Disease-Oriented Antitumour Drug Screening Program

One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

1977 • 1,556 citations

PROTOCOLS FOR SCREENING CHEMICAL AGENTS AND NATURAL PRODUCTS AGAINST ANIMAL TUMORS AND OTHER BIOLOGICAL SYSTEMS

1972 • 1,130 citations

Metastatic behavior of human tumor cell lines grown in the nude mouse.

1984 • 424 citations

Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis

1986 • 382 citations

Smoking and lung cancer: An overview

1985 • 357 citations

Advances in pharmacology and chemotherapy

1969 • 269 citations

Cancer Statistics, 1985

1985 • 185 citations

The response to chemotherapy of a variety of human tumour xenografts

1983 • 167 citations

Human brain tumor xenografts in nude mice as a chemotherapy model

1983 • 162 citations

Novel intrapulmonary model for orthotopic propagation of human lung cancers in athymic nude mice.

1987 • 161 citations

Characterization of a xenograft model of human ovarian carcinoma which produces ascites and intraabdominal carcinomatosis in mice.

1984 • 155 citations

Metastasis of human tumors in athymic nude mice

1979 • 155 citations

Growth of Human Tumor Xenografts Implanted under the Renal Capsule of Normal Immunocompetent Mice

1979 • 133 citations

Biology of the human malignant lymphomasIII. Intracranial heterotransplantation in the nude, athymic mouse

1976 • 122 citations

A Model of Human Cancer Metastasis: Extensive Spontaneous and Artificial Metastasis of a Human Pigmented Melanoma and Derived Variant Sublines in Nude Mice23

1984 • 106 citations

Preclinical drug development: rationale and methods.

1981 • 92 citations

Current NCI Preclinical Antitumor Screening in Vivo: Results of Tumor Panel Screening, 1976–1982, and Future Directions

1984 • 89 citations

Metastases of Human Melanomas Transplanted in “Nude” Mice2

1973 • 87 citations

Correlation between response to chemotherapy of human tumors in patients and in nude mice

1983 • 86 citations

Comparison of tumor response in nude mice and in the patients.

1984 • 79 citations

Clinical predictivity of transplantable tumor systems in the selection of new drugs for solid tumors: rationale for a three-stage strategy.

1983 • 75 citations

Biology of the Human Malignant Lymphomas

1978 • 62 citations

Evaluation of a “Nude” Mouse-Human Tumor Panel as a Predictive Secondary Screen for Cancer Chemotherapeutic Agents<xref ref-type="fn" rid="FN2">2</xref>

1979 • 58 citations

Predictive testing with the subrenal capsule assay

1984 • 53 citations

Comparison between macroscopic and microscopic evaluation of tumour responsiveness using the subrenal capsule assay

1983 • 45 citations

Evaluation of growth and histology of human tumor xenografts implanted under the renal capsule of immunocompetent and immunodeficient mice.

1985 • 37 citations

Childhood rhabdomyosarcoma xenografts: Responses to DNA-interacting agents and agents used in current clinical therapy

1984 • 35 citations

Improvements and limitations of the subrenal capsule assay for determining tumour sensitivity to cytostatic drugs

1984 • 31 citations

Microencapsulated tumor assay: new short-term assay for in vivo evaluation of the effects of anticancer drugs on human tumor cell lines.

1987 • 27 citations

Recent concepts of cancer metastasis and their implications for therapy.

1984 • 27 citations

Chemosensitivity profiles of human cancers assessed by the 6‐day SRC assay on serially xenografted tumors

1986 • 15 citations

Metabolic stability of experimental chemotherapeutic agents in hepatocyte: tumor cell co-cultures

1986 • 9 citations

Intrabronchial Implantation

1987 • 7 citations

Metastasis models for human tumors in athymic mice: useful models for drug development.

1987 • 7 citations

A New Human Osteosarcoma Strain (Os-Beppu) with a High Rate of Pulmonary Metastasis in Nude Mice

1984 • 7 citations

Deleted Work

1955 • 0 citations