Mutations of the ras protooncogenes in chronic myelogenous leukemia: a high frequency of ras mutations in bcr/abl rearrangement-negative chronic myelogenous leukemia

The Molecular Genetics of Philadelphia Chromosome–Positive Leukemias

1988 • 867 citations

Mutations in N-ras predominate in acute myeloid leukemia

1987 • 239 citations

RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes.

1987 • 231 citations

A point mutation at codon 13 of the N-ras oncogene in myelodysplastic syndrome

1987 • 231 citations

bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia

1986 • 186 citations

Transforming genes in chronic myelogenous leukemia.

1988 • 155 citations

Philadelphia chromosome‐negative chronic myelogenous leukaemia: a morphological reassessment

1985 • 109 citations

The site of the breakpoint within the bcr is a prognostic factor in Philadelphia-positive CML patients [see comments]

1988 • 96 citations

Ph1-Negative Chronic Granulocytic Leukemia: A Nonentity

1986 • 74 citations

Relationship between an activated N-ras oncogene and chromosomal abnormality during leukemic progression from myelodysplastic syndrome

1988 • 69 citations

Clinical and prognostic features of philadelphia chromosome-negative chronic myelogenous leukemia

1986 • 68 citations

Ras oncogene mutations are rare late stage events in chronic myelogenous leukemia

1989 • 66 citations

Rare occurrence of N-ras point mutations in Philadelphia chromosome positive chronic myeloid leukemia

1989 • 65 citations

Clinical evaluation of a DNA probe assay for the Philadelphia (Ph1) translocation in chronic myelogenous leukemia.

1988 • 64 citations

Transforming genes in human leukemia cells

1985 • 56 citations

Use of the Polymerase Chain Reaction Technique to Create Base-SpecificrasOncogene Mutations

1988 • 19 citations