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Abstract
References (11)
Defective N-oxidation of sparteine in man: A new pharmacogenetic defect
1979 • 647 citations
A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.
1980 • 544 citations
Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man
1984 • 368 citations
Mephenytoin hydroxylation deficiency in Caucasians: Frequency of a new oxidative drug metabolism polymorphism
1984 • 271 citations
In vitro inhibition studies of two isozymes of human liver cytochrome P-450. Mephenytoin p-hydroxylase and sparteine monooxygenase.
1985 • 173 citations
Genetic polymorphism of mephenytoin p(4′)‐hydroxylation: difference between Orientals and Caucasians.
1985 • 111 citations
Stereoselective metabolism of mephenytoin in man.
1981 • 75 citations
Mephenytoin hydroxylation deficiency: Kinetics after repeated doses
1984 • 62 citations
Stereoselective metabolism and disposition of the enantiomers of mephenytoin during chronic oral administration of the racemic drug in man.
1982 • 52 citations
Mephenytoin and sparteine pharmacogenetics in Canadian Caucasians
1984 • 41 citations
Sparteine oxidation by the human liver: Absence of inhibition by mephenytoin
1984 • 19 citations
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