Temperature-Sensitive Mutants of Avian RNA Tumor Viruses: A Review

Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus

1970 • 2,061 citations

Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses

1970 • 1,992 citations

Proteases and biological control

1976 • 1,380 citations

Agar suspension culture for the selective assay of cells transformed by polyoma virus

1964 • 1,265 citations

Control of proliferation in animal cells

1974 • 1,177 citations

Identification of a transformation-specific antigen induced by an avian sarcoma virus

1977 • 931 citations

AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES

1973 • 779 citations

Alteration of Cell-Surface Proteins by Viral Transformation and by Proteolysis

1973 • 666 citations

Episomes

1962 • 602 citations

Characteristics of an assay for Rous sarcoma virus and Rous sarcoma cells in tissue culture

1958 • 555 citations

Cell surface protein partially restores morphology, adhesiveness, and contact inhibition of movement to transformed fibroblasts.

1976 • 518 citations

Rous Sarcoma Virus: a Function required for the Maintenance of the Transformed State

1970 • 444 citations

Proteases and biological control

1975 • 412 citations

The effects of reciprocal changes in temperature on the transformed state of cells infected with a Rous sarcoma virus mutant

1971 • 411 citations

Purification of the DNA polymerase of avian myeloblastosis virus

1971 • 314 citations

Generation of avian myeloblastosis virus structural proteins by proteolytic cleavage of a precursor polypeptide

1975 • 308 citations

Hexose Transport in Normal and in Rous Sarcoma Virus-transformed Cells

1973 • 281 citations

A nonselective analysis of SV40 transformation of mouse 3T3 cells

1974 • 261 citations

Genetic recombinants and heterozygotes derived from endogenous and exogenous avian RNA tumor viruses

1973 • 245 citations

Mapping RNase T1-resistant oligonucleotides of avian tumor virus RNAs: sarcoma-specific oligonucleotides are near the poly(A) end and oligonucleotides common to sarcoma and transformation-defective viruses are at the poly(A) end

1975 • 241 citations

TRANSFORMATION OF PROPERTIES OF AN ESTABLISHED CELL LINE BY SV40 AND POLYOMA VIRUS

1964 • 236 citations

Adenylic Acid-rich Sequence in RNAs of Rous Sarcoma Virus and Rauscher Mouse Leukaemia Virus

1972 • 229 citations

Characteristics of two new avian tumor virus subgroups

1969 • 227 citations

Association of Viral Reverse Transcriptase with an Enzyme degrading the RNA Moiety of RNA-DNA Hybrids

1971 • 226 citations

Gel Electrophoresis of Avian Leukosis and Sarcoma Viral RNA in Formamide: Comparison with Other Viral and Cellular RNA Species

1973 • 223 citations

The low molecular weight RNAs of Rous sarcoma virus

1970 • 223 citations

Mapping of poly(A) sequences in the electron microscope reveals unusual structure of type C oncornavirus RNA molecules

1976 • 218 citations

Correlation between tumor induction and the large external transformation sensitive protein on the cell surface.

1976 • 213 citations

Spontaneous segregation of nontransforming viruses from cloned sarcoma viruses

1971 • 212 citations

Changes in membrane polypeptides that occur when chick embryo fibroblasts and NRK cells are transformed with avian sarcoma viruses

1974 • 211 citations

Temperature-sensitive changes in surface modulating assemblies of fibroblasts transformed by mutants of Rous sarcoma virus.

1976 • 208 citations

Novel human serum protein from fibroblast plasma membrane

1974 • 206 citations

The reverse transcriptase

1977 • 194 citations

The control of cellular morphology in embryonic cells infected with Rous sarcoma virus in vitro

1960 • 187 citations

Immunological relationships among envelope antigens of avian tumor viruses

1966 • 186 citations

Tumor Viruses: 1974

1974 • 185 citations

Genetics of RNA Tumor Viruses

1977 • 185 citations

Control of the Initiation of DNA Synthesis in 3T3 Cells: Serum Factors

1974 • 184 citations

Transcription of DNA from the 70 S RNA of Rous Sarcoma Virus I. Identification of a Specific 4 S RNA Which Serves as Primer

1974 • 184 citations

The nucleic acid of the Bryan strain of Rous sarcoma virus: purification of the virus and isolation of the nucleic acid.

1965 • 181 citations

Advances in Virus Research

1957 • 178 citations

Changes in microfilament organization and surface topogrophy upon transformation of chick embryo fibroblasts with Rous sarcoma virus.

1976 • 174 citations

Site on the RNA of an avian sarcoma virus at which primer is bound

1975 • 170 citations

Temperature-Dependent Alterations in Sugar Transport in Cells Infected by a Temperature-Sensitive Mutant of Rous Sarcoma Virus

1971 • 168 citations

Cleavage of Rous sarcoma viral polypeptide precursor into internal structural proteins in vitro involves viral protein p15.

1977 • 167 citations

Association of a protease (plasminogen activator) with a specific membrane fraction isolated from transformed cells.

1976 • 163 citations

Temperature sensitive mutants of an avian sarcoma virus

1969 • 160 citations

Ordered transcription of RNA tumor virus genomes

1976 • 157 citations

A physical map of the Rous sarcoma virus genome

1976 • 155 citations

Blocked, methylated 5′-terminal sequence in avian sarcoma virus RNA

1975 • 153 citations

Plasminogen Activator Production Accompanies Loss of Anchorage Regulation in Transformation of Primary Rat Embryo Cells by Simian Virus 40

1974 • 151 citations

Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H

1975 • 149 citations

Proteins of helper-dependent RSV

1971 • 149 citations

Polypeptides of avian RNA tumor viruses

1970 • 147 citations

Temperature-sensitive avian sarcoma viruses: A physiological comparison of twenty mutants

1973 • 144 citations

Comparison of immature (rapid harvest) and mature Rous sarcoma virus particles

1972 • 143 citations

Plasminogen, the Serum Proenzyme Activated by Factors from Cells Transformed by Oncogenic Viruses

1974 • 139 citations

Covalently closed circular DNA of avian sarcoma virus: Purification from nuclei of infected quail tumor cells and measurement by electron microscopy and gel electrophoresis

1976 • 136 citations

Surface Glycoproteins and Glycolipids of Chicken Embryo Cells transformed by a Temperature-sensitive Mutant of Rous Sarcoma Virus

1972 • 136 citations

Location of envelope-specific and sarcoma-specific oligonucleotides on RNA of Schmidt-Ruppin Rous sarcoma virus.

1976 • 133 citations

RD-114, baboon, and woolly monkey viral RNAs compared in size and structure

1976 • 133 citations

ANALYSIS OF THE DEFECTIVENESS OF ROUS SARCOMA VIRUS, II. SPECIFICATION OF RSV ANTIGENICITY BY HELPER VIRUS

1964 • 132 citations

A Mutation in a Rous Sarcoma Virus Gene That Controls Adenosine 3′,5′-Monophosphate Levels and Transformation

1972 • 130 citations

A Comparison of Membrane Proteins of Normal and Transformed Cells by Lactoperoxidase Labeling

1974 • 130 citations

Mapping of biological functions on RNA of avian tumor viruses: location of regions required for transformation and determination of host range.

1975 • 119 citations

Agglutination of Cells transformed by Rous Sarcoma Virus by Wheat Germ Agglutinin and Concanavalin A

1972 • 118 citations

Evidence for 30-40S RNA as Precursor of the 60-70S RNA of Rous Sarcoma Virus

1973 • 117 citations

The genome-associated, specific RNA binding proteins of avian and mammalian type C viruses

1977 • 113 citations

Reversion from transformed to normal phenotype by inhibition of protein synthesis in rat kidney cells infected with a temperature-sensitive mutant of Rous sarcoma virus.

1976 • 113 citations

Temperature-Dependent Transformation of Cells Infected with a Mutant of Bryan Rous Sarcoma Virus

1972 • 112 citations

Subunit structure of the glycoprotein complex of avian tumor virus

1976 • 109 citations

Polypeptides of avian RNA tumor viruses

1972 • 109 citations

Characterization of two conditional early mutants of Rous sarcoma virus

1973 • 107 citations

Virion and Tumor Cell Antigens of C-Type RNA Tumor Viruses

1974 • 106 citations

Translation of Rous sarcoma virus RNA in a cell-free system from ascites Krebs II cells.

1975 • 105 citations

Transcription of DNA from the 70 S RNA of Rous Sarcoma Virus II. Structure of a 4 S RNA Primer

1974 • 104 citations

The selective isolation of temperature-sensitive mutants of Rous sarcoma virus

1973 • 103 citations

Alterations in surface proteins in chicken cells transformed by temperature-sensitive mutants of Rous sarcoma virus

1975 • 103 citations

Structural Studies of Avian Myeloblastosis Virus: Comparison of Polypeptides in Virion and Core Component by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1974 • 100 citations

Distinguishable transformation-defective phenotypes among temperature-sensitive mutants of Rous sarcoma virus

1977 • 99 citations

DNA polymerase activity from two temperature-sensitive mutants of Rous sarcoma virus is thermolabile

1974 • 98 citations

Surface ruffles as markers for studies of cell transformation by Rous sarcoma virus.

1975 • 98 citations

The low molecular weight RNAs of Rous sarcoma virus

1970 • 93 citations

Characterization of the Low-Molecular-Weight RNAs Associated with the 70 S RNA of Rous Sarcoma Virus

1973 • 92 citations

Analysis of the defectiveness of Rous sarcoma virus

1964 • 90 citations

Synthesis of Viral DNA in the Cytoplasm of Duck Embryo Fibroblasts and in Enucleated Cells after Infection by Avian Sarcoma Virus

1974 • 89 citations

Genetic Recombination among Temperature-sensitive Mutants of Rous Sarcoma Virus

1974 • 87 citations

Phosphoproteins of Rous sarcoma viruses

1976 • 86 citations

Changes in phosphatidylinositol metabolism correlated to growth state of normal and Rous sarcoma virus-transformed Japanese quail cells.

1977 • 85 citations

The Chick Fibroblast Cell Surface after Transformation by Rous Sarcoma Virus

1974 • 84 citations

Studies on the Reverse Transcriptase of RNA Tumor Viruses. Structural Relatedness of Two Subunits of Avian RNA Tumor Viruses

1974 • 84 citations

RNA tumor viruses of pheasants: Characterization of avian leukosis subgroups F and G

1974 • 80 citations

Structure of the intermediates leading to the integrated provirus

1977 • 79 citations

Cell-surface antigens induced by avian RNA tumor viruses: Detection by immunoferritin technique

1972 • 78 citations

Conditional lethal mutants of avian sarcoma viruses

1971 • 77 citations

Characteristics of a conditional mutant of Rous sarcoma virus defective in ability to transform cells at high temperature

1972 • 76 citations

Role of surface modulating assemblies in growth control of normal and transformed fibroblasts.

1977 • 75 citations

Transformation of Chick-Embryo Fibroblasts by Wild-Type and Temperature-Sensitive Rous Sarcoma Virus Alters Adenylate Cyclase Activity

1973 • 75 citations

Evidence That a Precursor Glycoprotein Is Cleaved to Yield the Major Glycoprotein of Avian Tumor Virus

1977 • 69 citations

Identification of the 5' end of Rous sarcoma virus RNA.

1975 • 68 citations

RNA of replication-defective strains of Rous sarcoma virus.

1975 • 68 citations

Oncogenicity of avian leukosis viruses of different subgroups and of mutants of sarcoma viruses

1977 • 67 citations

Keeping the Computer Flag Flying

1971 • 64 citations

Terminal redundancy and the origin of replication of Rous sarcoma virus RNA.

1977 • 62 citations

An avian sarcoma virus mutant that is temperature sensitive for virion assembly

1976 • 62 citations

Determination of the defective function in two mutants of Rous sarcoma virus

1974 • 61 citations

In Vitro Synthesis of Rous Sarcoma Virus-Specific RNA is Catalyzed by a DNA-Dependent RNA Polymerase

1974 • 58 citations

Lipid studies of Rous sarcoma virus and host cell membranes

1972 • 57 citations

Observations on the Nature of a Genetic Cellular Resistance to Avian Tumor Viruses<xref ref-type="fn" rid="FN2">2</xref>

1968 • 56 citations

Distribution of envelope-specific and sarcoma-specific nucleotide sequences from different parents in the RNAs of avian tumor virus recombinants.

1976 • 55 citations

Growth stimulation of chick embryo neuroretinal cells infected with Rous sarcoma virus: Relationship to viral replication and morphological transformation

1976 • 54 citations

Plasminogen-independent fibrinolysis by proteases produced by transformed chick embryo fibroblasts.

1975 • 54 citations

Inhibition of protease activity in cultures of rous sarcoma virus-transformed cells: Effect on the transformed phenotype

1975 • 53 citations

Induction of Mutations in an RNA Tumour Virus by an Analogue of a DNA Precursor

1971 • 53 citations

Interference and Neutralization Studies with BRYAN Strain Rous Sarcoma Virus Synthesized in the Absence of Helper Virus

1969 • 53 citations

Differential expression of transformation in rat and chicken cells infected with an avian sarcoma virus ts mutant

1973 • 52 citations

Alterations in lipid acyl group composition and membrane structure in cells transformed by Rous sarcoma virus

1976 • 50 citations

Polypeptides of avian RNA tumor viruses

1970 • 49 citations

Ribosomal rna in avian leukosis virus particles

1971 • 48 citations

Temperature sensitive mutants of avian sarcoma viruses

1975 • 48 citations

High molecular weight RNAs from Rous sarcoma virus and Moloney murine leukemia virus contain two subunits.

1976 • 47 citations

Proposal for Numbering Mutants of Avian Leukosis and Sarcoma Viruses

1974 • 46 citations

Translation of Avian Myeloblastosis Virus RNA in a Cell-Free Lysate of Escherichia coli

1972 • 46 citations

Transformation-defective mutants of avian sarcoma viruses: The genetic relationship between conditional and nonconditional mutants

1976 • 43 citations

A replication defective mutant of Rous sarcoma virus which fails to make a functional reverse transcriptase

1975 • 42 citations

Defective cleavage of a precursor polypeptide in a temperature-sensitive mutant of avian sarcoma virus

1976 • 39 citations

Molecular events during the interaction of envelopes of myxo- and RNA-tumor viruses with cell membranes. A 270 MHz 1H nuclear magnetic resonance study

1978 • 37 citations

Adenylate cyclase activity is decreased in chick embryo fibroblasts transformed by wild type and temperature sensitive Schmidt-Ruppin Rous sarcoma virus

1973 • 37 citations

Transformation by a Temperature Sensitive Mutant of Rous Sarcoma Virus in the Absence of Serum

1975 • 37 citations

Rous-sarcoma-virus-transformed fibroblasts having low levels of plasminogen activator.

1976 • 35 citations

Glycolipids of chick embryo fibroblasts infected with temperature-sensitive mutants of avian sarcoma viruses

1977 • 34 citations

Temperature-sensitive mutants of avian sarcoma viruses

1976 • 34 citations

Accumulation of water during transformation of cells by an avian sarcoma virus

1974 • 31 citations

A PARTIAL GENETIC MAP OF ROUS SARCOMA VIRUS RNA: LOCATION OF POLYMERASE, ENVELOPE AND TRANSFORMATION MARKERS

1976 • 29 citations

Cell-free synthesis of two proteins unique to RNA of transforming virions of Rous sarcoma virus.

1977 • 28 citations

Plasma membrane alteration associated with malignant transformation in culture.

1975 • 27 citations

Characterization of “early” temperature-sensitive mutants of avian sarcoma viruses: Biological properties, thermolability of reverse transcriptase in vitro, and synthesis of viral DNA in infected cells

1976 • 26 citations

Conditional lethal mutants of avian sarcoma viruses

1971 • 24 citations

Analysis on the reproducing and cell-transforming capacities of a temperature sensitive mutant (ts 334) of avian sarcoma virus B77

1973 • 24 citations

Strain specificity of changes in adenylate cyclase activity in cells transformed by avian sarcoma viruses

1975 • 24 citations

Complementation of functions required for cell transformation by double infection with RSV mutants

1972 • 24 citations

Phenotypes of Rous sarcoma virus-transformed fibroblasts: An argument for a multifunctionalSrc gene product

1977 • 23 citations

Comparative Morphology of Avian and Murine Leukemia Viruses<xref ref-type="fn" rid="FN1">2</xref>

1971 • 20 citations

A mutant of rous sarcoma virus with a conditional defect in the determinant(s) of viral host range

1977 • 19 citations

Expression of tumor-specific surface antigens on cells infected with temperature-sensitive mutants of avian sarcoma virus

1975 • 18 citations

The defective maturation of viral progeny with a temperature-sensitive mutant of avian sarcoma virus

1976 • 17 citations

A temperature-sensitive mutant of Rous sarcoma virus that is defective for replication

1973 • 17 citations

Temperature-sensitive mutants of avian sarcoma viruses: Genetic recombination between multiple or coordinate mutants and avian leukosis viruses

1976 • 17 citations

Cell surface antigen induced by avian tumor viruses in hamster cells transformed by a temperature-sensitive mutant of rous sarcoma virus

1974 • 16 citations

Tumor producing capacity of temperature sensitive mutants of avian sarcoma viruses in chicks.

1973 • 16 citations

Expression of Virus Specific Morphological Cell Transformation Induced in E nucleated Cells

1976 • 11 citations

Cooperative transformation studies with temperature-sensitive mutants of Rous sarcoma virus

1976 • 9 citations

Agglutinability of Rous Cells by Concanavalin A: Study with a Temperature-Sensitive RSV Mutant and Inhibitors of Macromolecular Synthesis

1973 • 8 citations

Influence of defective virion core proteins on RNA maturation with an avian sarcoma virus

1977 • 8 citations

Characterization of a conditional mutant of Rous sarcoma virus with alterations in early and late functions of cell transformation

1975 • 8 citations

MANUSCRIPT PREPARATION

1976 • 6 citations