Cardioprotection by K_ATP channels in wild-type hearts and hearts overexpressing A₁-adenosine receptors

Cardioprotective Effect of Diazoxide and Its Interaction With Mitochondrial ATP-Sensitive K ⁺ Channels

1997 • 1,032 citations

Mitochondrial ATP-Dependent Potassium Channels

1998 • 825 citations

Hypoxic Dilation of Coronary Arteries Is Mediated by ATP-Sensitive Potassium Channels

1990 • 600 citations

Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery.

1995 • 558 citations

Mitochondrial ATP-sensitive K⁺channels modulate cardiac mitochondrial function

1998 • 313 citations

Blockade of ischaemic preconditioning in dogs by the novel ATP dependent potassium channel antagonist sodium 5-hydroxydecanoate

1992 • 282 citations

Role of myocardial ATP-sensitive potassium channels in mediating preconditioning in the dog heart and their possible interaction with adenosine A1-receptors.

1992 • 255 citations

Cardioprotective effects of 70-kDa heat shock protein in transgenic mice.

1996 • 252 citations

A comparison of adenosine-induced cardioprotection and ischemic preconditioning in dogs. Efficacy, time course, and role of KATP channels.

1994 • 195 citations

Adenosine A1 receptor mediated protection of the globally ischemic isolated rat heart

1990 • 182 citations

Anti-ischemic effects of the potassium channel activators pinacidil and cromakalim and the reversal of these effects with the potassium channel blocker glyburide.

1989 • 173 citations

Transgenic Mice Overexpressing Glutathione Peroxidase are Resistant to Myocardial Ischemia Reperfusion Injury

1996 • 171 citations

Ischemic preconditioning depends on interaction between mitochondrial K_ATPchannels and actin cytoskeleton

1999 • 168 citations

ATP-sensitive potassium channel is essential to maintain basal coronary vascular tone in vivo

1992 • 163 citations

Cardioprotection provided by adenosine receptor activation is abolished by blockade of the KATP channel

1994 • 158 citations

Transgenic A ₁ adenosine receptor overexpression increases myocardial resistance to ischemia

1997 • 158 citations

Specific block of the anti-ischemic actions of cromakalim by sodium 5-hydroxydecanoate.

1991 • 140 citations

The Ischemia-selective KATPChannel Antagonist, 5-Hydroxydecanoate, Blocks Ischemic Preconditioning in the Rat Heart

1997 • 124 citations

Ischemic cardioprotection by ATP-sensitive K+ channels involves high-energy phosphate preservation

1993 • 119 citations

Adenosine improves recovery of postischemic myocardial function via an adenosine A1 receptor mechanism

1992 • 114 citations

Pharmacologic Profile of Cromakalim in the Treatment of Myocardial Ischemia in Isolated Rat Hearts and Anesthetized Dogs

1990 • 94 citations

Potassium channels and preconditioning of isolated rabbit cardiomyocytes: Effects of glyburide and pinacidil

1995 • 93 citations

Direct preconditioning of cardiac ventricular myocytes via adenosine A1 receptor and KATP channel

1996 • 87 citations

Protective Effects of ATP-Sensitive Potassium-Channel Openers in Experimental Myocardial Ischemia

1994 • 83 citations

Extracellular superoxide dismutase transgene overexpression preserves postischemic myocardial function in isolated murine hearts.

1996 • 79 citations

Effects of glibenclamide and nicorandil on cardiac function during ischemia and reperfusion in isolated perfused rat hearts

1991 • 77 citations

Limitation of myocardial infarct size in the rabbit by ischaemic preconditioning is abolished by sodium 5-hydroxydecanoate

1996 • 75 citations

Glyburide-reversible cardioprotective effect of BMS-180448 is independent of action potential shortening

1995 • 73 citations

Protection from ischaemic-reperfusion injury with adenosine pretreatment is reversed by inhibition of ATP sensitive potassium channels

1993 • 68 citations

Reduction of ischemic damage in isolated rat hearts by the potassium channel opener, RP 52891

1990 • 67 citations

Effects of potassium channel modulation during global ischaemia in isolated rat heart with and without cardioplegia

1992 • 65 citations

Adenosine A₃-receptor stimulation attenuates postischemic dysfunction through K_ATP channels

1999 • 53 citations

Species differences in susceptibility to ischemic injury and responsiveness to myocardial protection.

1990 • 51 citations

Transgenic A1Adenosine Receptor Overexpression Markedly Improves Myocardial Energy State During Ischemia-Reperfusion

1998 • 45 citations

Transgenic overexpression of cardiac A₁adenosine receptors mimics ischemic preconditioning

2000 • 43 citations

Comparison ofIn VitroPreconditioning Responses of Isolated Pig and Rabbit Cardiomyocytes: Effects of a Protein Phosphatase Inhibitor, Fostriecin

1997 • 42 citations

Effect of potassium channel blockade on the anti-ischemic actions of mechanistically diverse agents.

1991 • 40 citations

Dynamics of Early Postischemic Myocardial Functional Recovery

1995 • 34 citations

Thromboxane Receptor Antagonist BMS-180291, but Not Aspirin, Reduces the Severity of Pacing-Induced Ischemia in Dogs

1994 • 28 citations

Assessment of ischemic injury and protective interventions: the Langendorff versus the working rat heart preparation.

1990 • 28 citations

Effects of Cromakalim and Glibenclamide on Myocardial High Energy Phosphates and Intracellular pH During Ischemia-reperfusion:31P NMR Studies

1997 • 27 citations

Effects of graded perfusion and isovolumic work on epicardial and venous adenosine and cytosolic metabolism

1991 • 24 citations

K_ATP‐channel activation: effects on myocardial recovery from ischaemia and role in the cardioprotective response to adenosine A₁‐receptor stimulation

1998 • 11 citations

Mitochondrial respiratory chain enzyme activities and coenzyme Q in hypertrophied human left ventricles with aortic valve stenosis

1990 • 7 citations