Detection of Micrometastasis Through Tissue-Specific Gene Expression: Its Promise and Problems

Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma

1994 • 647 citations

Micrometastases and Survival in Stage II Colorectal Cancer

1998 • 602 citations

Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patients

1992 • 563 citations

Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy

1995 • 458 citations

Prediction of early relapse in patients with operable breast cancer by detection of occult bone marrow micrometastases.

1991 • 454 citations

Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction.

1994 • 382 citations

Limitations of reverse-transcriptase polymerase chain reaction analyses for detection of micrometastatic epithelial cancer cells in bone marrow.

1997 • 290 citations

Detection of tumor cells in bone marrow of patients with primary breast cancer: a prognostic factor for distant metastasis.

1992 • 289 citations

Sensitive detection of rare circulating neuroblastoma cells by the reverse transcriptase-polymerase chain reaction.

1992 • 190 citations

Prostate-specific antigen is a new favorable prognostic indicator for women with breast cancer.

1995 • 173 citations

Immunocytological detection of bone marrow micrometastasis in operable non-small cell lung cancer.

1993 • 170 citations

Increased detection of mammary carcinoma cells in marrow smears using antisera to epithelial membrane antigen

1981 • 167 citations

Specificity of reverse transcriptase polymerase chain reaction assays designed for the detection of circulating cancer cells is influenced by cytokines in vivo and in vitro

1998 • 160 citations

Polymerase Chain Reaction Detection of Circulating Melanocytes as a Prognostic Marker in Patients With Melanoma

1995 • 150 citations

Detection of α-fetoprotein mRNA, an indicator of hematogenous spreading hepatocellular carcinoma, in the circulation: A possible predictor of metastatic hepatocellular carcinoma

1994 • 135 citations

A polymerase chain reaction-based semiquantitative assessment of malignant melanoma cells in peripheral blood.

1995 • 129 citations

Detection of Circulating Tumor Cells in Colorectal Cancer by Immunobead-PCR Is a Sensitive Prognostic Marker for Relapse of Disease

1995 • 117 citations

Neuroblastoma cell detection by reverse transcriptase‐polymerase chain reaction (RT‐PCR) for tyrosine hydroxylase mRNA

1994 • 111 citations

Diagnosis of micrometastases by the amplification of tissue-specific genes

1995 • 105 citations

Reverse Transcriptase Polymerase Chain Reaction for Prostate Specific Antigen in the Management of Prostate Cancer

1997 • 98 citations

Molecular staging of prostate cancer. II. A comparison of the application of an enhanced reverse transcriptase polymerase chain reaction assay for prostate specific antigen versus prostate specific membrane antigen.

1995 • 83 citations

Detection of Isolated Mammary Carcinoma Cells in Marrow of Patients with Primary Breast Cancer

1983 • 74 citations

Molecular Stating of Prostate Cancer. II. A Comparison of the Application of an Enhanced Reverse Transcriptase Polymerase Chain Reaction Assay for Prostate Specific Antigen Versus Prostate Specific Membrane Antigen

1995 • 63 citations

Polymerase chain reaction detection of circulating melanocytes as a prognostic marker in patients with melanoma

1995 • 62 citations

Immunobead RT-PCR: A Sensitive Method for Detection of Circulating Tumor Cells

1997 • 57 citations

Mutational spectra of a 100-base pair mitochondrial DNA target sequence in bronchial epithelial cells: a comparison of smoking and nonsmoking twins.

1998 • 40 citations

Detection of Prostatic Specific Membrane Antigen Messenger RNA Using Immunobead Reverse Transcriptase Polymerase Chain Reaction

1999 • 38 citations

Reverse transcriptase-polymerase chain reaction for prostate-specific antigen may be a prognostic indicator in breast cancer

1996 • 35 citations

Quality management and influential factors for the detection of single metastatic cancer cells by reverse transcriptase polymerase chain reaction.

1997 • 34 citations

Methods for Detection of Micrometastatic Carcinoma Cells in Bone Marrow, Blood and Lymph Nodes

1995 • 19 citations

Identification of point mutations in mixtures by capillary electrophoresis hybridization

1998 • 14 citations