Alpha-fetoprotein molecular heterogeneity

Alpha-Fetoprotein in Ontogenesis and its Association with Malignant Tumors

1971 • 892 citations

Protein-carbohydrate interaction

1967 • 632 citations

ALPHA-FETOPROTEIN IN THE ANTENATAL DIAGNOSIS OF ANENCEPHALY AND SPINA BIFIDA

1972 • 603 citations

PRODUCTION OF EMBRYONAL α-GLOBULIN BY TRANSPLANTABLE MOUSE HEPATOMAS

1963 • 601 citations

Onco-developmental gene expression

1976 • 401 citations

Glycoproteins

1973 • 373 citations

Selective removal of albumin from plasma by affinity chromatography

1973 • 293 citations

Studies of carcino‐fetal proteins. III. Development of a radioimmunoassay for α‐fetoprotein. Demonstration of α‐fetoprotein in serum of healthy human adults

1971 • 281 citations

Synthesis of Serum Albumin, Prealbumin, α-Foetoprotein, α1-Antitrypsin and Transferrin by the Human Yolk Sac

1970 • 280 citations

The presence of fatty acids in human alpha-fetoprotein.

1978 • 192 citations

THE ANONYMOUS WHITE TABLET.

1965 • 177 citations

Studies of carcino‐fetal proteins. II. Biochemical comparison of α‐fetoprotein from human fetuses and patients with hepatocellular cancer

1971 • 163 citations

α-Fetoprotein induces suppressor T cells in vitro

1977 • 162 citations

α Foetoprotein and serum albumin show sequence homology

1976 • 160 citations

Estrogen-binding properties of rat, mouse and man fetospecific serum proteins. Demonstration by immuno-autoradiographic methods

1972 • 154 citations

Studies of carcino‐fetal proteins: Physical and chemical properties of human α‐fetoprotein

1971 • 143 citations

Human α-Fetoprotein

1972 • 132 citations

Fetus-specific serum proteins in several mammals and their relation to human α-fetoprotein

1967 • 131 citations

α1-Fetoprotein: Separation of two molecular variants by affinity chromatography with concanavalin A-agarose

1973 • 123 citations

Developmental changes in carbohydrate moiety of human alpha‐fetoprotein

1978 • 114 citations

Structure and Function of Alpha-Fetoprotein

1977 • 113 citations

Rat alpha-fetoprotein: isolation, characterization and estrogen-binding properties

1974 • 110 citations

Purification and chemical characterization of α‐fetoprotein from rat and mouse

1974 • 88 citations

Binding of nonpolar molecules by crystalline concanavalin A

1973 • 85 citations

Interaction of concanavalin A, a phytohemagglutinin, with model substrates

1966 • 81 citations

Biosynthesis of Glycoproteins and its Relationship to Heterogeneity

1969 • 77 citations

Microheterogeneity of rat, mouse and human α1-fetoprotein as revealed by polyacrylamide gel electrophoresis and by crossed immuno-affino-electrophoresis with different lectins

1979 • 75 citations

The detection of alpha 1-fetoprotein in patients with viral hepatitis.

1974 • 72 citations

PRENATAL DIAGNOSIS CHEMICAL METHODS

1976 • 63 citations

The Lack of Estrogen Binding by Human α-Fetoprotein¹

1974 • 62 citations

Reactivity of amniotic fluid alpha-fetoprotein with concanavallin A in diagnosis of neural tube defects.

1979 • 60 citations

MECHANISMS BY WHICH AMNIOTIC-FLUID ALPHA-FETOPROTEIN MAY BE INCREASED IN FETAL ABNORMALITIES

1976 • 58 citations

Rat α-fetoprotein—III. Refinement of radioimmunoassay for detection of 1 ng rat α1F

1973 • 56 citations

Suppression of the primary cell-mediated immune response by human α1-fetoprotein in vitro

1977 • 55 citations

Isolation of two forms of rat alpha-fetoprotein and comparison of their binding parameters with estradiol-17β

1975 • 54 citations

Developmental changes in the plasma protein pattern of the rat

1963 • 54 citations

Immunosuppression by mouse sialylated α-foetoprotein

1977 • 53 citations

Alpha‐1 antitrypsin (AAT) and alphafoetoprotein (AFP) in sera of patients with germ‐cell neoplasms: Value as tumour markers in patients with endodermal sinus tumour (yolk sac tumour)

1977 • 52 citations

Starch-gel electrophoresis of “purified” albumins

1961 • 49 citations

Developmental changes in microheterogeneity of foetal plasma glycoproteins of mice

1973 • 49 citations

The effect of purified α-fetoprotein on in vitro assays of cell-mediated immunity

1977 • 47 citations

α-Foetoprotein: Purification on Sepharose-linked Concanavalin-A

1973 • 46 citations

Affinity chromatography of human, rat and mouse α‐fetoprotein on estradiol‐sepharose adsorbents

1975 • 44 citations

Two methods for the separation of human α-fetoprotein and albumin

1978 • 42 citations

Concanavalin A affinity molecular variants of alpha-fetoprotein in neonatal rat serum and in the serum of rats bearing hepatomas.

1977 • 42 citations

High level of alpha‐fetoprotein in sera of adult mice

1973 • 41 citations

Augmentation of proliferation of human mixed lymphocyte culture by human alpha-fetoprotein.

1977 • 41 citations

Sialyltransferase: regulation of α-foetoprotein microheterogeneity during development (Short Communication)

1973 • 41 citations

Affinity chromatography purification of rat αn₁‐foetoprotein

1974 • 40 citations

Developmental microheterogeneity of mouse α-fetoproteins: purification and partial characterization

1976 • 39 citations

Rabbit α-fetoprotein: Immunochemical purification and partial characterization

1973 • 39 citations

Conditions affecting the immunosuppressive properties of human alpha-fetoprotein.

1977 • 39 citations

Alpha-fetoproteins produced by the yolk sac and the liver are glycosylated differently

1978 • 38 citations

Post-albumin, a foetal-specific rat plasma protein: Purification, physicochemical and immunological studies

1967 • 37 citations

ISOELECTRIC FOCUSING OF HUMAN α‐FETOPROTEIN: AN AID IN PURIFICATION AND CHARACTERIZATION OF MICROHETEROGENEITY

1973 • 37 citations

Conditions Affecting the Immunosuppressive Properties of Human α-Fetoprotein

1977 • 36 citations

Characterization and isolation of nine rat alpha-fetoprotein variants by gel electrophoresis and lectin affinity chromatography

1977 • 36 citations

[Hereditary tyrosinemia and alpha-1-fetoprotein. I. Clinical value of alpha-fetoprotein in hereditary tyrosinemia].

1973 • 36 citations

Studies on human α-fetoprotein

1977 • 36 citations

Microheterogeneity of rat alpha-fetoprotein.

1975 • 36 citations

Rat alpha-fetoprotein heterogeneity comparative chemical study of the two electrophoretic variants and their ricinus lectin-binding properties

1977 • 35 citations

VARIANTS OF α-FETOPROTEIN

1970 • 34 citations

Yolk sac: Site of developmental microheterogeneity of mouse α-fetoprotein

1976 • 34 citations

Binding of 17β-estradiol by variants of α-fetoprotein in rat amniotic fluid

1976 • 34 citations

Augmentation of Proliferation of Human Mixed Lymphocyte Culture by Human α-Fetoprotein

1977 • 32 citations

Electrophoretic preparation of the two rat α‐fetoprotein variants

1975 • 32 citations

Inhibition of human lymphocyte transformation by human alpha-foetoprotein (HAFP): studies on the mode of HAFP action and the role of HAFP polymorphism.

1978 • 31 citations

MICROHETEROGENEITY OF RAT α‐FETOPROTEIN*

1975 • 30 citations

Subcellular distribution and molecular heterogeneity of .alpha.1-fetoprotein in newborn rat liver

1979 • 29 citations

Amniotic fluid proteins: Evidence for the presence of fetal plasma glycoproteins in mouse amniotic fluid

1972 • 28 citations

Rat iso-alpha1-fetoproteins purification and interaction with estradiol-17β

1977 • 28 citations

Purification and estrogen binding properties of mouse alpha1-fetoprotein and of two forms of the protein with different affinities for concanavalin-A

1977 • 25 citations

Isolation and characterization of alpha-foetoprotein from foetal pigs

1976 • 24 citations

Affinity chromatography of mouse alpha-fetoprotein (AFP) on oestradiol-sepharose adsorbents—isolation and properties

1977 • 24 citations

A postsynthetic modification of human α-fetoprotein controls its immunosuppressive potency

1977 • 23 citations

LIVER DIFFERENTIATION AND THE ESTROGEN‐BINDING PROPERTIES OF α‐FETOPROTEIN*

1975 • 22 citations

Binding of estrogens by α-fetoprotein in rat amniotic fluid

1974 • 21 citations

HUMAN α‐FETOPROTEIN IMMUNOCHEMICAL ANALYSIS OF ISOPROTEINS*

1975 • 21 citations

Effect of alpha-fetoprotein and other serum factors derived from hepatoma-bearing rats on the mixed lymphocyte response.

1976 • 21 citations

Rat alpha-fetoprotein: In vitroproduction of four molecular variants by clonal cell lines

1977 • 21 citations

Chromatography of non-human albumins on Cibacron Blue—agarose

1979 • 20 citations

Alpha-fetoprotein and human lymphocyte subpopulations.

1977 • 20 citations

Physico-chemical analogies of rat alpha-fetoprotein and rat serum albumin

1977 • 19 citations

Binding of estrogens to molecular variants of rat alpha‐fetoprotein

1977 • 19 citations

Immunochemical purification and characterization of ovine α-fetoprotein

1977 • 19 citations

Physicochemical approach to the purification of human alpha1-fetoprotein from the ascites fluid of a hepatoma-bearing patient.

1978 • 18 citations

Isolation and characterization of α-fetoprotein from the mouse hepatoma bw7756

1977 • 18 citations

Rat alpha‐fetoprotein heterogeneity

1977 • 18 citations

Alpha‐Fetoprotein

1978 • 17 citations

Human Alpha-Fetoprotein: Immunosuppressive Activity and Microheterogeneity

1978 • 17 citations

Effect of α-Fetoprotein and Other Serum Factors Derived from Hepatoma-Bearing Rats on the Mixed Lymphocyte Response

1976 • 16 citations

Fluorescence studies of the interactions of serum albumin and rat alpha1-fetoprotein with aflatoxin B1

1978 • 15 citations

Immunosuppressive Activity of Isolated Rat and Human Fetoproteins

1978 • 15 citations

Murine alpha-fetoprotein: N-terminal amino acid sequence and C-terminal residue

1978 • 14 citations

EFFECT OF CHEMICAL MODIFICATION ON THE IMMUNO‐GENICITY OF HOMOLOGOUS α‐FETOPROTEIN*

1975 • 14 citations

α-Fetoprotein and Human Lymphocyte Subpopulations

1977 • 12 citations

Statement by the Editors

1978 • 11 citations

Heterogeneity of human α-fetoprotein as revealed by isoelectric focusing in urea-containing gels

1978 • 11 citations

Bovine alpha-fetoprotein

1978 • 10 citations

Purification of alpha1-fetoprotein.

1976 • 10 citations

Purification of alpha1-fetoprotein.

1976 • 10 citations

Separation and characterization of two bovine alpha1-fetoprotein molecular variants by concanavalin A-Sepharose chromatography

1978 • 10 citations

Serum alpha-feto-protein. 3. Electrophoresis of sera from cases of primary cancer of the liver: an electrophoretic variant.

1969 • 9 citations

Sialyltransferase in fetal tissues: Incorporation of sialic acid into endogenous and exogenous glycoprotein acceptors

1976 • 9 citations

Oestrone binding properties of nine molecular variants of rat alpha-foetoprotein

1978 • 8 citations

Mouse Alpha‐fetoprotein: Genetic Studies

1978 • 7 citations

Circular dichroic study of rat alphafetoprotein

1977 • 7 citations

N‐terminal Amino Acid Sequences and C‐terminal Residues of Rat Alpha‐fetoprotein Electrophoretic Variants, ‘Fast’ and ‘Slow’

1978 • 7 citations

Copper(II)‐Binding Ability of Human Alpha‐fetoprotein

1978 • 7 citations

Heterogeneity of Human Alpha‐fetoprotein (HAFP) as Revealed by Agarose Gel Electrophoresis and Iso‐electric Focusing in Ureaacrylamide Gels

1978 • 6 citations

Alpha‐fetoprotein and albumin in experimentally‐induced exencephaly in the rat

1977 • 5 citations

Metabolism of Concanavalin A-Affinity Molecular Variants of Alpha-Fetoprotein in Rats<xref ref-type="fn" rid="FN2">2</xref>

1978 • 5 citations

Interactions of Alpha‐fetoprotein and Other Proteins with Concanavalin A

1978 • 5 citations

Purification and Physical Characterization of Human Alpha‐fetoprotein from Cord Blood and from Ascites Fluid of Individuals with Hepatocellular Carcinoma

1978 • 5 citations

Identification of plasma proteins in the palate of fetal mice

1972 • 5 citations

Induction of hepatomas secreting large amounts of alpha-fetoprotein

1977 • 5 citations

Molecular heterogeneity of alpha‐fetoprotein secreted by primary and transplantable hepatocellular carcinomas

1979 • 3 citations

Concanavalin A‐affinity Molecular Variants of Rat AFP: Differences Among Amniotic Fluid, Fetal Serum, Newborn Serum and Maternal Serum

1978 • 3 citations