Physiology and Biochemistry of Blood Coagulation

Preparation and Properties of Serum and Plasma Proteins. IV. A System for the Separation into Fractions of the Protein and Lipoprotein Components of Biological Tissues and Fluids^1a,b,c,d

1946 • 1,815 citations

Protides of the Biological Fluids

1969 • 1,623 citations

An Enzyme Cascade in the Blood Clotting Mechanism, and its Function as a Biochemical Amplifier

1964 • 1,099 citations

Waterfall Sequence for Intrinsic Blood Clotting

1964 • 1,088 citations

THE STRUCTURE OF A CHYMOTRYPTIC PEPTIDE FROM PSEUDOMONAS CYTOCHROME C-551

1963 • 829 citations

Rapid Attainment of Sedimentation Equilibrium

1958 • 762 citations

The Thromboplastin Generation Test

1953 • 632 citations

Evidence for an Active-Center Histidine in Trypsin through Use of a Specific Reagent, 1-Chloro-3-tosylamido-7-amino-2-heptanone, the Chloromethyl Ketone Derived from N^α-Tosyl-L-lysine^*

1965 • 521 citations

Metabolism and Physiological Significance of Lipids

1963 • 482 citations

MEASUREMENT OF PLATELET ADHESIVENESS. A SIMPLE IN VITRO TECHNIQUE DEMONSTRATING AN ABNORMALITY IN VON WILLEBRAND'S DISEASE.

1963 • 479 citations

A FAMILIAL HEMORRHAGIC TRAIT ASSOCIATED WITH A DEFICIENCY OF A CLOT-PROMOTING FRACTION OF PLASMA 1

1955 • 454 citations

Christmas Disease

1952 • 424 citations

New Hemophilia-like Disease Caused by Deficiency of a Third Plasma Thromboplastin Factor.

1953 • 402 citations

Two-stage Procedure For the Quantitative Determination of Prothrombin Concentration*

1949 • 379 citations

Preparation of Phenyl Thiohydantoins from Some Natural Amino Acids.

1950 • 368 citations

Parahaemophilia; haemorrhagic diathesis due to absence of a previously unknown clotting factor.

1947 • 333 citations

Identification and Semiquantitative Determination of Phenyl Thiohydantoins.

1956 • 304 citations

Experiments on a new Clotting Factor (Factor VII)

1951 • 300 citations

High-potency Antihæmophilic Factor Concentrate prepared from Cryoglobulin Precipitate

1964 • 300 citations

CONGENITAL SPCA DEFICIENCY: A HITHERTO UNRECOGNIZED COAGULATION DEFECT WITH HEMORRHAGE RECTIFIED BY SERUM AND SERUM FRACTIONS 1

1951 • 278 citations

MASSIVE THROMBOSIS PRODUCED BY FATTY ACID INFUSION*

1963 • 275 citations

Stuart Clotting Defect. I. Segregation of an Hereditary Hemorrhagic State from the Heterogeneous Group Heretofore Called “Stable Factor” (SPCA, Proconvertin, Factor VII) Deficiency

1957 • 267 citations

Activation of plasma by contact with glass: evidence for a common reaction which releases plasma kinin and initiates coagulation

1958 • 255 citations

Plasma Throinboplastin Component (PTC) Deficiency: A New Disease Resembling Hemophilia

1952 • 251 citations

THE ACTION OF THROMBIN ON SYNTHETIC SUBSTRATES

1954 • 250 citations

Platelet Clumping Produced by Connective Tissue Suspensions and by Collagen.

1962 • 233 citations

Die Chemie der Blutgerinnung

1905 • 230 citations

Protides of the Biological Fluids

1960 • 226 citations

Fibrinogen Detroit—a Molecular Defect in the N-terminal Disulphide Knot of Human Fibrinogen?

1968 • 225 citations

Activation of hageman factor by collagen

1968 • 221 citations

The Contact Phase of Blood Coagulation

1964 • 218 citations

The coagulation of blood

1908 • 214 citations

STUDIES ON THE ACTION OF HAGEMAN FACTOR: EVIDENCE THAT ACTIVATED HAGEMAN FACTOR IN TURN ACTIVATES PLASMA THROMBOPLASTIN ANTECEDENT*

1961 • 210 citations

The Physiology of Blood Platelets.

1965 • 210 citations

A ‘New’ Coagulation Defect

1956 • 207 citations

Metabolism and Physiological Significance of Lipids

1965 • 197 citations

The Importance of Activation of Antihemophilic Globulin and Proaccelerin by Traces of Thrombin in the Generation of Intrinsic Prothrombinase Activity

1963 • 193 citations

AMINO ACID COMPOSITION OF SIMPLE PROTEINS

1946 • 190 citations

Role of hageman factor in the initiation of clotting by glass

1958 • 188 citations

PARAHÆMOPHILIA

1947 • 176 citations

The isolation and purification of a bovine-plasma protein which is a substrate for the coagulant fraction of Russell's-viper venom

1962 • 170 citations

A Correlation between Surface Charge and Coagulant Action of Phospholipids

1961 • 169 citations

Observations on the interaction of phospholipids and certain clotting factors in prothrombin activator formation

1964 • 169 citations

Blood clotting enzymology

1968 • 169 citations

Assay of Plasma Antihaemophilic Globulin (AHG)*

1959 • 167 citations

The Reaction between Bovine Brain Tissue Factor and Factors VII and X^*

1966 • 165 citations

Molecular configuration and thermodynamic parameters from intrinsic viscosities

1950 • 160 citations

ON THE CONSTITUTION OF PROTHROMBIN

1943 • 154 citations

ACTIVATION OF HAGEMAN FACTOR BY SOLUTIONS OF ELLAGIC ACID.

1964 • 152 citations

The phospholipid requirement of tissue factor in blood coagulation

1968 • 151 citations

Studies on the formation of the prothrombin-converting complex

1967 • 147 citations

THE INTERRELATIONSHIP OF COAGULATION OF PLASMA AND RELEASE OF PEPTIDES

1963 • 145 citations

The fractionation of Russell's-viper (Vipera russellii) venom with special reference to the coagulant protein

1962 • 142 citations

MECHANISMS OF ACTIVATION OF C'1 ESTERASE IN HEREDITARY ANGIONEUROTIC EDEMA PLASMA IN VITRO

1968 • 142 citations

The Demise of John Hageman

1968 • 141 citations

The formation of thromboplastin in human blood

1953 • 134 citations

THE ACTIVE PRINCIPLE OF PLACENTAL TOXIN: THROMBOPLASTIN; ITS INACTIVATOR IN BLOOD: ANTITHROMBOPLASTIN

1947 • 132 citations

The Nembutal Metabolic Rate as an Aid in the Study of Thyroid Function

1957 • 123 citations

SOME PROPERTIES OF PURIFIED PROTHROMBIN AND ITS ACTIVATION WITH SODIUM CITRATE

1950 • 123 citations

Chemistry and Physiology of the Fibrinogen-Fibrin Transition

1964 • 120 citations

SERUM AC-GLOBULIN: FORMATION FROM PLASMA AC-GLOBULIN; ROLE IN BLOOD COAGULATION; PARTIAL PURIFICATION; PROPERTIES; AND QUANTITATIVE DETERMINATION

1948 • 117 citations

The Activation of Christmas Factor (Factor IX) by Activated Plasma Thromboplastin Antecedent (Activated Factor XI)^*

1962 • 116 citations

The Purification of Activated Hageman Factor (Activated Factor XII)^*

1962 • 115 citations

Initiation of blood coagulation by glass and related surfaces

1957 • 115 citations

Hematologic and coagulation studies in various animal species.

1959 • 114 citations

Biophysical mechanisms in vascular homeostasis and intravascular thrombosis

1966 • 113 citations

Note on the Adsorption of Thrombin on Fibrin

1945 • 112 citations

THE ACTIVE SITE OF THROMBIN

1958 • 110 citations

HEMOPHILIA. I. THE ABNORMAL COAGULATION OF THE BLOOD AND ITS RELATION TO THE BLOOD PLATELETS

1936 • 109 citations

A CONCENTRATE OF HUMAN ANTIHÆMOPHILIC FACTOR

1957 • 108 citations

CONTRIBUTION TO THE PATHOGENESIS OF HEMOPHILIA

1947 • 107 citations

The Coagulant Action of Russell's Viper Venom; The Use of Antivenom in Defining its Reaction with a Serum Factor

1961 • 107 citations

Prothrombin and accessory factors

1953 • 104 citations

PLATELET PHOSPHATIDES. THEIR FATTY ACID AND ALDEHYDE COMPOSITION AND ACTIVITY IN DIFFERENT CLOTTING SYSTEMS*

1962 • 103 citations

ACTIVE HAGEMAN FACTOR: A PLASMA LYSOKINASE OF THE HUMAN FIBRINOLYTIC SYSTEM*

1962 • 101 citations

The mode of action of Hageman factor in the release of plasma kinin

1960 • 100 citations

The Function of Ac-Globulin in Blood Clotting

1947 • 99 citations

Relationship between Factor V and Activated Factor X in the Generation of Prothrombinase

1967 • 99 citations

THE INFLAMMATORY PROCESS IN ACUTE GOUTY ARTHRITIS. I. ACTIVATION OF HAGEMAN FACTOR BY SODIUM URATE CRYSTALS.

1965 • 98 citations

Reaction Sequence of Blood Coagulation

1967 • 97 citations

A FACTOR IN SERUM WHICH ACCELERATES THE CONVERSION OF PROTHROMBIN TO THROMBIN: I. ITS DETERMINATION AND SOME PHYSIOLOGIC AND BIOCHEMICAL PROPERTIES

1949 • 96 citations

Bovine Factor X. II. Characterization of purified Factor X. Alterations in zone electrophoretic and chromatographic behavior occurring during purification

1968 • 96 citations

An Antithrombin Reaction Related to Prothrombin Activation

1953 • 95 citations

Blood-Clotting Enzymology

1968 • 94 citations

Role of Hageman Factor in the Activation of Vasodilator Activity in Human Plasma

1961 • 94 citations

The Activation of Antihemophilic Factor (Factor VIII) by Activated Christmas Factor (Activated Factor IX)^*

1964 • 90 citations

Hemorrhagic Disease in an Infant Due to Deficiency of a Previously Undescribed Clotting Factor

1952 • 89 citations

The Purification of Bovine Antihaemophilic Globulin

1955 • 87 citations

ON VARIOUS PROPERTIES OF THROMBOPLASTIN (AQUEOUS TISSUE EXTRACTS)

1935 • 86 citations

Studies on the Antithrombin and Heparin Co-factor Activities of a Fraction Adsorbed from Plasma by Aluminum Hydroxide

1955 • 85 citations

The pathogenesis of hereditary hæmophilia

1911 • 85 citations

A new high-potency glycine-precipitated antihemophilic factor (AHF) concentrate. Treatment of classical hemophilia and hemophilia with inhibitors.

1968 • 84 citations

The Purification of Antihaemophilic Globulin from Animal Plasma

1955 • 83 citations

Platelet Phosphatides: Their Separation, Identification, and Clotting Activity1

1958 • 80 citations

Formation of Prothrombin Converting Activity

1967 • 79 citations

THE EFFECT OF GLASS UPON THE ACTIVITY OF THE VARIOUS PLASMA CLOTTING FACTORS

1955 • 79 citations

The initial stages of blood coagulation

1953 • 78 citations

THE NATURE OF PLASMA ANTITHROMBIN ACTIVITY

1950 • 78 citations

Intermediate Stages in the Formation of Blood Thromboplastin

1956 • 77 citations

Phospholipid structure and thromboplastic activity

1958 • 77 citations

Congenital Afibrinogenemia

1954 • 77 citations

Congenital dysfibrinogenemia: fibrinogen detroit

1969 • 77 citations

Inhibition of Hageman factor activation

1968 • 76 citations

Titration of Active Centers in Thrombin Solutions. Standardization of the Enzyme^*

1965 • 75 citations

The Identification and Synthesis of Activated Plasma Thromboplastin Component (PTC')

1963 • 74 citations

PATHOGENESIS OF INFLAMMATION

1965 • 74 citations

A New High-Potency Glycine-Precipitated Antihemophilic Factor (AHF) Concentrate

1968 • 74 citations

STUDIES ON THE PATHOGENESIS OF THROMBOSIS: AN EXPERIMENTAL "HYPERCOAGULABLE" STATE INDUCED BY THE INTRAVENOUS INJECTION OF ELLAGIC ACID.

1964 • 73 citations

THE PROTHROMBIN CONVERSION ACCELERATOR OF SERUM (SPCA): ITS PARTIAL PURIFICATION AND ITS PROPERTIES COMPARED WITH SERUM AC-GLOBULIN 1

1950 • 73 citations

Partial purification of bovine plasma kallikreinogen, its activation by the Hageman factor

1968 • 72 citations

THROMBOPLASTIC FACTORS IN PLATELETS AND RED BLOOD CELLS: OBSERVATIONS ON THEIR CHEMICAL NATURE AND FUNCTION IN IN VITRO COAGULATION *

1960 • 72 citations

Some Physicochemical Properties of Bovine Thrombin

1961 • 71 citations

Thrombin and the Interaction of Factors VIII and IX

1965 • 71 citations

The Preparation and Assay of a Christmas‐Factor (Factor IX) Concentrate and its Use in the Treatment of Two Patients

1961 • 71 citations

The amino acid composition of bovine prothrombin

1954 • 70 citations

The action of thromboplastic substances

1953 • 70 citations

Preparation and properties of thrombin

1968 • 70 citations

New One-Stage Procedures for the Quantitative Determination of Prothrombin and Labile Factor

1950 • 70 citations

Bovine Thrombin

1967 • 69 citations

CERTAIN PHYSICAL PROPERTIES OF BOVINE PROTHROMBIN

1953 • 68 citations

Hageman factor, a novel sialoglycoprotein with esterase activity

1965 • 68 citations

THE CONDITION OF THE BLOOD IN HEMOPHILIA, THROMBOSIS AND PURPURA

1914 • 68 citations

THE EFFECT OF DIISOPROPYL FLUOROPHOSPHATE ON THE PROTEINASE AND ESTERASE ACTIVITIES OF THROMBIN AND ON PROTHROMBIN AND ITS ACTIVATORS

1956 • 67 citations

Influence of Surface Charge of Phospholipids on their Clot-Promoting Activity.

1962 • 67 citations

The potent antihemophilic globulin concentrate derived from a cold insoluble fraction of human plasma: characterization and further data on preparation and clinical trial.

1966 • 67 citations

The isolation of factor V from bovine plasma

1967 • 66 citations

THE THROMBOPLASTIC PROTEIN: STRUCTURE, PROPERTIES, DISINTEGRATION

1944 • 66 citations

Clinical Use of Human Prothrombin Complexes

1965 • 65 citations

The Reaction between Activated Plasma Thromboplastin Antecedent and Diisopropylphosphofluoridate^*

1964 • 65 citations

Defects in the Early Stages of Blood Coagulation: A Report of Four Cases

1958 • 65 citations

Preparation of Highly Purified Prothrombin Complex

1968 • 64 citations

Chromatographic Analysis of the Activation of Human Prothrombin with Human Thrombokinase^*

1966 • 64 citations

A FACTOR IN SERUM WHICH ACCELERATES THE CONVERSION OF PROTHROMBIN TO THROMBIN

1949 • 64 citations

THE CLOTTING BEHAVIOR OF HUMAN “PLATELET-FREE” PLASMA: EVIDENCE FOR THE EXISTENCE OF A “PLASMA THROMBOPLASTIN”

1949 • 63 citations

PURIFICATION OF PROTHROMBIN AND THROMBIN: CHEMICAL PROPERTIES OF PURIFIED PREPARATIONS

1940 • 63 citations

A Study of the Metabolism in Addison's Disease. II

1947 • 63 citations

Coagulation, Hemorrhage and Thrombosis

1955 • 62 citations

New Data on Hageman Factor and Plasma Thromboplastin Antecedent: The Role of ‘Contact’ in the Initial Phase of Blood Coagulation

1960 • 62 citations

Isolation and some properties of prethrombin and autoprothrombin III

1967 • 62 citations

Availability of Platelet Factor 3 and Activation of Factor XII in Thrombasthenia

1965 • 60 citations

The Similarity of the Action of Phosphatidyl-ethanolamine and Platelets in Blood Coagulation

1956 • 60 citations

CHROMATOGRAPHIC ISOLATION OF PLASMA PROTHROMBIN AND TRANS-α-GLUCOSYLASE

1958 • 60 citations

ULTRACENTRIFUGAL ISOLATION FROM LUNG TISSUE OF A MACROMOLECULAR PROTEIN COMPONENT WITH THROMBOPLASTIC PROPERTIES

1942 • 60 citations

Prothrombin synthesis in the dog

1964 • 59 citations

Hageman Trait and PTA Deficiency; the Role of Contact of Blood with Glass

1959 • 58 citations

THE SIMILAR EFFECT OF CHYLOMICRA AND ETHANOLAMINE PHOSPHATIDE ON THE GENERATION OF THROMBIN DURING COAGULATION

1956 • 58 citations

Differentiation of Hemophilia into Two Groups

1953 • 57 citations

THE PURIFICATION OF PROTHROMBIN

1938 • 57 citations

Phospholipid structure and thromboplastic activity

1958 • 57 citations

Plasma Thromboplastin Component (PTC) A Hitherto Unrecognized Blood Coagulation Factor Case Report of PTC Deficiency

1953 • 57 citations

Tularemia Endotoxin

1940 • 56 citations

The Interaction of Factors VIII and IX

1964 • 56 citations

ACTIVATION OF HAGEMAN FACTOR BY SATURATED FATTY ACIDS

1962 • 56 citations

A STUDY OF THE CLOTTING DEFECT IN HEMOPHILIA

1939 • 56 citations

The Role of Hageman Factor in the Initiation of Blood Coagulation

1959 • 56 citations

Hageman Factor: Alterations in Physical Properties during Activation

1965 • 56 citations

Studies on the Relationship between the Colloidal State and Clot-promoting Activity of Pure Phosphatidylethanolamines

1959 • 55 citations

STUDIES ON THE CHEMISTRY OF BLOOD COAGULATION

1941 • 55 citations

Purification and Quantitative Determination of Platelet Factor 3

1955 • 55 citations

Purification and Properties of Bovine Factor X: Molecular Changes During Activation^*

1964 • 55 citations

THE PURIFICATION OF THROMBIN

1938 • 55 citations

Preparation of a human plasma fraction rich in prothrombin, proconvertin, Stuart factor, and PTC and a study of its activity and toxicity in rabbits and man.

1959 • 54 citations

Über die Lokalisierung von gerinnungsphysiologischen Aktivitäten in submikroskopischen Strukturen der Thrombocyten

1959 • 54 citations

DEMONSTRATION OF ANTITHROMBOPLASTIC ACTIVITY IN NORMAL AND HEMOPHILIC PLASMAS

1943 • 53 citations

NEUTRALIZATION OF AUTOPROTHROMBIN C ACTIVITY WITH ANTITHROMBIN

1964 • 53 citations

Glass Surface and Blood Coagulation

1956 • 52 citations

Purification of a Bovine Plasma Protein (Factor VII) Which Is Required for the Activity of Lung Microsomes in Blood Coagulation

1966 • 52 citations

Preparation and Properties of Prothrombin

1959 • 52 citations

The inhibition of thrombin by diisopropyl phosphorofluoridate

1956 • 51 citations

The Activity of Lung Microsomes in Blood Coagulation

1964 • 51 citations

Antihaemophilic globulin: preparation by an improved cryoprecipitation method and clinical use.

1967 • 50 citations

HAGEMAN FACTOR AND CAPILLARY PERMEABILITY

1959 • 50 citations

The Conversion of Human Prothrombin to Thrombin by Sodium Citrate

1965 • 50 citations

FATTY ACID COMPOSITION OF THE SERUM LIPIDS OF PIGS GIVEN DIFFERENT AMOUNTS OF LINOLEIC ACID

1963 • 50 citations

The Hydrolysis of Carbobenzoxy-l-tyrosine p-Nitrophenyl Ester by Various Enzymes

1959 • 49 citations

MYOCARDIAL INFARCTION ASSOCIATED WITH SEVERE FACTOR-XII DEFICIENCY

1966 • 49 citations

Hemophilia and Other Hemorrhagic States

1960 • 48 citations

STUDIES ON PROTHROMBIN: PURIFICATION, INACTIVATION WITH THROMBIN, AND ACTIVATION WITH THROMBOPLASTIN AND CALCIUM

1948 • 48 citations

Human thrombin: Isolation and stability

1965 • 48 citations

Proconvertin, the New Clotting Factor

1951 • 48 citations

The preparation and properties of a stable factory V from bovine plasma

1967 • 48 citations

Purification and Properties of Bovine Factor V: A Change of Molecular Size During Blood Coagulation^*

1964 • 47 citations

The Activation of Factor X by Extracts of Rabbit Brain

1964 • 47 citations

Inhibition of Autoprothrombin C Activity with Plasma

1962 • 46 citations

The acetylation of thrombin.

1959 • 46 citations

Sedimentation of plasma antihemophilic factor

1961 • 46 citations

FURTHER STUDIES ON THE PURIFICATION OF THROMBIN

1958 • 46 citations

Fibrinolytic Activity of Purified Thrombin

1950 • 46 citations

Prothrombin Conversion Factor of Dicumarol Plasma.

1948 • 46 citations

Some Effects of Divalent Cations on the Clotting Mechanism and the Platelets of EDTA Blood

1958 • 45 citations

Natural Formation of Petroleum-like Hydrocarbons From "Oil Shales"

1947 • 45 citations

Viscous Metamorphosis of Blood Platelets: A Study of the Relationship to Coagulation Factors and Fibrin Formation

1958 • 44 citations

Transglutaminase activity of the fibrin crosslinking enzyme

1966 • 44 citations

Activation of a Permeability Factor in Plasma by Contact with Glass

1958 • 44 citations

Conversion of Prothrombin to Autoprothrombin II (Platelet Cofactor II) and Its Relation to the Blood Clotting Mechanisms

1956 • 44 citations

Isolation and purification of bovine and canine prothrombin

1965 • 44 citations

Purification and Properties of Rat Prothrombin

1967 • 44 citations

Application of Continuous Flow Electrophoresis to the Study of the Blood Coagulation Proteins and the Fibrinolytic Enzyme System. I. Normal Human Materials1

1958 • 44 citations

The Activation of Stuart Factor (Factor X) by Activated Antihemophilic Factor (Activated Factor VIII)^*

1965 • 44 citations

Amino Acid Composition of Human Plasma Prothrombin

1968 • 43 citations

Inactivation of Prothrombin by Purified Thrombin Solutions.

1939 • 43 citations

Morphologic alterations of human blood platelets during early phases of clotting. Electron microscopic observations of thin sections.

1962 • 43 citations

FURTHER OBSERVATIONS ON THE EFFECTS OF ETHANOLAMINE PHOSPHATIDE ON PLASMA COAGULATION

1956 • 43 citations

AUTOPROTHROMBIN C: A SECOND ENZYME FROM PROTHROMBIN

1962 • 42 citations

Some Experiments on Factors Concerned in the Formation of Thrombin

1916 • 42 citations

Sequence Theories of Blood Coagulation re-evaluated with reference to Lipid–Protein Interactions

1967 • 41 citations

Myocardial Infarction in a Patient with a Hageman (Factor XII) Defect

1966 • 41 citations

Viscous Metamorphosis of Platelets: Morphological Platelet Changes induced, by an Intermediate Product of Blood Thromboplastin Formation

1956 • 41 citations

Thrombin-catalyzed hydrolysis of p-nitrophenyl esters

1962 • 40 citations

Some activation characteristics of the prethrombin subunit of prothrombin

1965 • 40 citations

STUDIES OF HEMOPHILIA. II. THE ASSAY OF THE ANTIHEMOPHILIC CLOT-PROMOTING PRINCIPLE IN NORMAL HUMAN PLASMA WITH SOME OBSERVATIONS ON THE RELATIVE POTENCY OF CERTAIN PLASMA FRACTIONS 1

1948 • 40 citations

A Prothrombin Conversion Accelerator in Serum

1949 • 40 citations

IDENTIFICATION OF A THROMBOPLASTIN INHIBITOR IN SERUM AND IN PLASMA 1

1953 • 39 citations

Studies on the site of action of a circulating anticoagulant in disseminated lupus erythematosus

1963 • 39 citations

Release of Factor VIII (Antihaemophilic Factor) from Perfused Organs and Tissues

1967 • 39 citations

THE CAUSE OF THE DELAYED CLOTTING OF HEMOPHILIC BLOOD

1926 • 39 citations

The Levels of Antihemophilic Globulin and Proaccelerin in Fresh and Bank Blood

1959 • 39 citations

The Activity of Human Placenta Microsomes and Brain Particles in Blood Coagulation

1966 • 39 citations

PURIFICATION AND SOME PROPERTIES OF AUTOPROTHROMBIN C

1963 • 38 citations

On the Occurrence of Polymorphic Human Prothrombin

1968 • 38 citations

Thromboplastin: Nomenclature and Preparation of Protein-Free Material Different From Platelet Factor 3 or Lipid Activator

1958 • 38 citations

THE ACETYLATION OF THROMBIN

1959 • 37 citations

INFLUENCE OF ERYTHROCYTES ON THE COAGULATION OF BLOOD

1960 • 37 citations

Pathways to Blood Coagulation Product I Formation

1963 • 37 citations

Carbohydrate and nitrogen distribution during the activation of purified prothrombin in sodium citrate solution

1953 • 37 citations

Experiments on the Nature of the Prothrombin‐Converting Principle: Alteration of Proaccelerin Thrombin

1967 • 37 citations

Activation of Phospholipid Thromboplastin by Lecithin

1956 • 37 citations

The antithrombin activity of human plasma

1954 • 37 citations

A Simple Procedure for Separation of Prothrombin and Accelerator Globulin from Citrated Human Plasma.

1953 • 36 citations

Utilization of the Antihemophilic Factor During Clotting of Canine Blood and Plasma

1951 • 36 citations

Separation of Plasma Thromboplastin Antecedent (PTA) and Hageman Factor (HF) from Human Plasma.

1960 • 36 citations

Preparation of Human Plasma Prothrombin and Some of Its Sedimentation Properties

1963 • 36 citations

Antihemophilic Factor Release by Perfused Liver and Spleen: Relationship to Hemophilia

1967 • 35 citations

Thrombin-E as a Fibrinolytic Enzyme

1960 • 35 citations

Some Biochemical and Electrophoretic Studies on Purified Prothrombin, Factor VII (Proconvertin) and Factor X (Stuart)

1960 • 35 citations

Effect of Russell's Viper Venom (Stypven) on Stuart Clotting Defect

1956 • 35 citations

MODE OF ACTION OF COUMARIN DRUGS

1955 • 35 citations

The fifth coagulation factor (‘Factor V’). Preparation and properties

1948 • 34 citations

Immunchemische untersuchungen mit prothrombin und thrombin

1959 • 34 citations

Bridge Anticoagulant: A Hitherto Unrecognized Blood Clotting Inhibitor in Haemophilic and Christmas‐Disease Plasma. A Simple Method for its Demonstration

1958 • 34 citations

Reactions of Stuart Factor and Factor VII with Brain and Factor V

1959 • 33 citations

Blood Clotting Mechanisms: Three Basic Reactions

1969 • 33 citations

Formation of Autoprothrombin in Solutions Containing Purified Prothrombin and Purified Platelet Factor 3

1955 • 33 citations

The Activation and Consumption of Factor X in Recalcified Plasma

1964 • 33 citations

STUDIES ON THE CLOT-PROMOTING ACTIVITY OF GLASS

1956 • 32 citations

The Chemical Nature of the Lipid Activator in Blood Coagulation

1962 • 32 citations

The Preparation for Therapeutic Use of a Concentrate of Factor IX Containing also Factors II, VII and X

1967 • 32 citations

Some Properties of the Platelet-Connective Tissue Mixed Agglutination Reaction

1962 • 32 citations

Esterase and Clotting Activities Derived from Citrate Activation of Human Prothrombin

1967 • 32 citations

PURIFICATION OF THROMBIN

1942 • 31 citations

STABILITY OF PROTHROMBIN AND Ac-GLOBULIN IN STORED HUMAN PLASMA AS INFLUENCED BY CONDITIONS OF STORAGE

1948 • 31 citations

Prothrombin Conversion Factors in Blood Coagulation

1951 • 31 citations

Purification and Physiological Properties of Factor VII from Plasma and Serum. Separation from Prothrombin

1953 • 30 citations

Some Physicochemical Properties of Bovine Autoprothrombin II

1962 • 30 citations

Properties of plasma thromboplastin antecedent (PTA) in relation to blood coagulation.

1955 • 30 citations

The anti‐coagulants in blood and serum

1912 • 29 citations

Phospholipid Antithromboplastin

1957 • 29 citations

Terminal amino acids of bovine prothrombin and thrombin preparations

1960 • 29 citations

Purification and Identification of Brain Phospholipides Associated with Thromboplastic Activity

1958 • 29 citations

Purification and Stabilization of Factor V

1963 • 29 citations

Cephalin, Protamine and the Antithromboplastic Activity of Normal and Hemophilic Plasmas.

1943 • 28 citations

Symposium: What Is Hemophilia?: Hemophilic Syndromes and Hemophilia

1954 • 28 citations

A Normal Inhibitor of the Blood Coagulation Contact Reaction Product

1965 • 28 citations

PROPERTIES OF BOVINE Ac-GLOBULIN CONCENTRATES AND METHODS OF PREPARATION

1963 • 28 citations

THROMBOPLASTIC CELL COMPONENT, THE LIPOPROTEIN OF ERYTHROCYTES AND PLATELETS

1957 • 28 citations

Lipids in blood clotting

1965 • 28 citations

Some catechol compounds other than noradrenaline and adrenaline in brains

1963 • 27 citations

The Mechanism of Action of Human Accelerator Globulin and Its Relation to Other Clotting Factors

1954 • 27 citations

The preparation of prothrombin derivatives and an indication of their properties

1956 • 27 citations

Properties of Bovine Anti-Hemophilic Factor

1953 • 27 citations

Prethrombin as a New Sub-unit of Prothrombin

1966 • 27 citations

INFLUENCE OF THE CONTACTING SURFACE ON THE COAGULABILITY AND ANTICEPHALIN ACTIVITY OF NORMAL AND HEMOPHILIC PLASMAS

1945 • 27 citations

ON THE EVOLUTION OF BLOOD CLOTTING THEORY

1952 • 27 citations

Transformation of Prothrombin into Thrombin

1954 • 27 citations

INACTIVATION OF PURIFIED AUTOPROTHROMBIN I WITH ANTITHROMBIN

1964 • 26 citations

Activation of Plasma Thromboplastinogen and Evidence of an Inhibitor.

1948 • 26 citations

Prothrombin activation with cathepsin C

1963 • 26 citations

Fingerprints of DNS-labeled protein digests on a millimicromole scale

1967 • 26 citations

Adsorption of hageman factor (factor XII) on collagen

1964 • 26 citations

Effect of Acute Liver Damage on Ac-Globulin Activity of Plasma

1948 • 26 citations

Thromboplastic activity of phosphatidylethanolamine from natural and synthetic sources

1963 • 26 citations

Isolation of Platelet Cofactor I From Plasma and Some Properties of the Preparation

1957 • 25 citations

Proteolytic activity of purified bovine Hageman factor☆

1964 • 25 citations

Co-Thromboplastin, a Probable Factor in Coagulation of Blood

1950 • 25 citations

Inflammatory process in acute gouty arthritis. 3. Vascular permeability-enhancing activity in normal human synovial fluid; induction by Hageman factor activators; and inhibition by Hageman factor antiserum.

1967 • 24 citations

Isolation of Human Thrombin.

1962 • 24 citations

Prothrombokinase and the Three Stages of Blood Coagulation

1947 • 24 citations

FRACTIONATION OF PLASMA GLOBULIN FOR PROTHROMBIN, THROMBOKINASE, AND ACCESSORY THROMBOPLASTIN

1951 • 24 citations

Lipids of Human Platelets and Their Action on the Blood Coagulation Process

1964 • 24 citations

Purification of Plasma Thromboplastin Factor B (Plasma Thromboplastin Component) and Its Identification as a Beta ₂ Globulin

1954 • 24 citations

Thrombin as a Proteolytic Enzyme

1954 • 23 citations

The Complex Mechanisms of the Quick Prothrombin Test and the Effect of Dicumarol

1950 • 23 citations

Über die Inaktivierung von Blutthrombokinase

1957 • 23 citations

THE ACTION OF HEPARIN IN THE PREVENTION OF PROTHROMBIN CONVERSION

1956 • 23 citations

Some Factors that Influence Utilization of Antihemophilic Activity During Clotting.

1957 • 23 citations

DEVELOPMENT OF INCREASED FACTOR VII ACTIVITY DURING THE SPONTANEOUS COAGULATION OF BLOOD

1961 • 23 citations

An Accelerator of Prothrombin Activation Derived From Prothrombin

1955 • 23 citations

TAMe Esterase Activity of Blood Thrombokinase after Repeated Electrophoretic Fractionations.

1960 • 23 citations

Separation and Molecular Weight Estimation of Coagulation and Fibrinolytic Proteins by Sephadex Gel Filtration.

1964 • 23 citations

HAGEMAN FACTOR AND IN VIVO ACTIVATION OF FIBRINOLYSIS.

1964 • 22 citations

Irrwege der Blutgerinnungsforschung

1936 • 22 citations

ACTION OF THROMBIN ON LYSINE SUBSTRATES¹

1957 • 22 citations

Plasma Thromboplastin Antecedent

1955 • 22 citations

Surface Activation of Plasma Clotting: A Function of Hageman Factor

1958 • 22 citations

Sensitivity of thrombin and autoprothrombin C to selected enzyme inhibitors

1965 • 22 citations

Effects of Intravenous Phospholipid Containing Phosphatidyl Serine on Blood Clotting with Particular Reference to the Russell's Viper Venom Time

1962 • 22 citations

Sphingosine as Inhibitor of Prothrombin Activation With Thromboplastin or With Threone

1957 • 22 citations

Factor IX in Intravascular and Extravascular Blood Coagulation

1962 • 22 citations

The Reaction of Blood Coagulation Factors with Brain Extract

1955 • 22 citations

Purification and Isolation of Certain Intermediates Formed Prior to the Activation of Prothrombin

1953 • 22 citations

Activation of Factors XII (Hageman) and XI (PTA) by Skin Contact.

1966 • 21 citations

SEPARATION OF AUTOPROTHROMBIN III FROM BOVINE PROTHROMBIN PREPARATIONS

1964 • 21 citations

STUDIES ON THE CHEMISTRY OF BLOOD COAGULATION

1937 • 21 citations

Identification of the Free Carboxyl Groups in Peptides

1951 • 21 citations

Die Blutplättchen des Hämophilen Blutes

1924 • 20 citations

Outstanding Characteristics of Thrombokinase Isolated from Bovine Plasma

1963 • 20 citations

Reactivity of Stored Plasma to Thrombin, with Reference to the Fibrinogen Conversion Accelerator and Heparinoid Activity

1957 • 20 citations

The Purification of Factor VIII (Antihaemophilic Globulin)

1963 • 20 citations

Experiments with Factor VIII Separated from Fibrinogen by Electrophoresis in Free Buffer Film

1966 • 20 citations

The active center of thrombin and trypsin

1959 • 19 citations

EFFECT OF BLOOD THROMBOKINASE, AS INFLUENCED BY SOY BEAN TRYPSIN INHIBITOR; ULTRACENTRIFUGATION, AND ACCESSORY FACTORS

1955 • 19 citations

Studtes on Proconvertin (Factor VII) II. Purification

1964 • 19 citations

N-Terminal Amino Acids of Human and Bovine Prothrombin.

1958 • 19 citations

Blood Coagulation: Reactions Leading to Prothrombin Activation

1965 • 19 citations

Application of Paper Electrophoresis to Separation of Blood-Clotting Factors

1954 • 19 citations

Evaluation of Disulfide Bonds and Sulfhydryl Groups in the Blood Clotting Mechanism

1954 • 19 citations

HEMOPHILIA AND OTHER HEMORRHAGIC STATES

1961 • 19 citations

CHROMATOGRAPHIC PURIFICATION OF HUMAN SERUM ACCELERATOR GLOBULIN 1

1956 • 19 citations

Differential Consumption of Coagulation Factors Resulting from Activation of the Extrinsic (Tissue Thromboplastin) or the Intrinsic (Foreign Surface Contact) Pathways

1967 • 18 citations

Conversion of Prothrombin into Thrombin

1961 • 17 citations

Thromboplastin. I. Phospholipid Moiety of Thromboplastin.

1960 • 17 citations

Hageman Factor in Plasma Foreign Surface Reactions

1958 • 16 citations

Hageman Factor Deficiency (Hageman Trait)

1962 • 16 citations

THE ELECTROPHORETIC PROPERTIES OF THE THROMBOPLASTIC PROTEIN FROM LUNGS

1941 • 16 citations

INACTIVATION OF THROMBOPLASTIN IN HUMAN BLOOD

1955 • 16 citations

[Purification of antihemophilic factor VIII (AHF)].

1961 • 16 citations

Phosphatidyl Serine and Blood Coagulation

1958 • 15 citations

PLASMA A<scp>c</scp>-GLOBULIN ACTIVITY

1947 • 15 citations

The Reduction of Autoprothrombin II Activity with Dicumarol

1956 • 15 citations

Preparation of Water Insoluble Thrombin.

1964 • 15 citations

The Purification of Factor VIII (Antihaemophilic Globulin)

1966 • 15 citations

The role of factor V in the formation of blood thromboplastin.

1957 • 15 citations

Sphingosine as an Inhibitor of Blood Clotting

1957 • 15 citations

Inactivation of Hageman factor by diisopropylfluorophosphate (DFP).

1960 • 15 citations

Activation of Prothrombin by Platelets Plus Globulin.

1948 • 14 citations

The Activation of Proaccelerin

1965 • 14 citations

Klinische Untersuchungen �ber die Gerinnungsfaktoren Prothrombin, Faktor V und Faktor VII bei Lebererkrankungen und ihre Beeinflussung durch Vitamin K1 und Synka-Vit

1953 • 14 citations

The coagulation of blood: Preliminary survey of thrombin and autoprothrombin zymogen structure

1969 • 14 citations

THE SEPARATION OF AUTOPROTHROMBIN I_cFROM BOVINE PROTHROMBIN PREPARATIONS

1964 • 14 citations

Purified Platelet Phospholipids and Blood Coagulation

1963 • 14 citations

Brief Report: Factor VIII (AHF) Concentration in pH 6.5 Citrate-Plasma

1966 • 13 citations

Chromatography of Blood Thrombokinase on ‘DEAE’-Cellulose

1960 • 13 citations

INTERACTION OF BOVINE AUTOPROTHROMBIN C WITH PHOSPHOLIPIDS AND DIVALENT CATIONS

1964 • 13 citations

A prothrombin activator in serum, and its significance in certain hemorrhagic diseases.

1948 • 13 citations

A Method for Preparing Plasma Factor VIII (Antihemophilic Globulin) Concentrate

1966 • 13 citations

FUNCTION OF Ac-GLOBULIN AND LIPID IN BLOOD CLOTTING

1963 • 13 citations

PREPARATION OF THROMBOKINASE FROM BOVINE PLASMA

1959 • 13 citations

Natürlich vorkommende Koagulationsinhibitoren

1958 • 13 citations

Plasma Thromboplastin Component (PTC) Potency of Plasma Fractions.

1953 • 12 citations

Autoprothrombin II of human origin

1961 • 12 citations

Clearance of Blood Coagulation Product I in Rabbits.

1960 • 12 citations

Purification and crystallization of horse prothrombin

1967 • 12 citations

The Disintegration of Macromolecular Tissue Lipoproteins

1944 • 12 citations

Generation of coagulation product I and its interaction with platelets and phospholipids

1961 • 12 citations

New Inhibitors of the First Stage of the Blood-clotting Process

1951 • 12 citations

Blood Clotting: The Plasma Procoagulants

1959 • 12 citations

In‐Vivo Study on the Relation between Bridge Anticoagulant and Antihaemophilic Globulin

1958 • 12 citations

Total Synthesis of Unsaturated Phosphatidylserine and its Activity in Clotting Systems

1963 • 12 citations

Concentrated Antihemophilic Factor (AHF) from Outdated Blood

1967 • 12 citations

HUMAN ANTIHÆMOPHILIC FACTOR THE PREPARATION IN A HOSPITAL OF A CONCENTRATE FOR CLINICAL USE

1963 • 11 citations

CONVERSION OF PROTHROMBIN TO AUTOPROTHROMBIN II

1956 • 11 citations

THE CLOTTING OF THE BLOOD OF AN AMPHIBIAN, BUFO MARINUS LINN

1961 • 11 citations

Note on the mechanism of activation of human accelerator globulin by thrombin

1955 • 11 citations

Untersuchungen zur Funktion der Anti-Plasmathrombokinase

1960 • 11 citations

Toxicity of Blood Clotting Factors

1962 • 11 citations

Anticephalin Activity and the Prothrombin Conversion Rate of Normal and Hemophilic Plasmas.

1944 • 11 citations

Die Bestimmung der Antithrombinaktivitäten des Plasmas

1955 • 11 citations

The Degeneration of Brain Thromboplastin in the Presence of Normal Serum

1957 • 11 citations

Isolation of Human Plasma Prothrombin of High Specific Activity by Gel Filtration.

1963 • 11 citations

Protein thrombokinase and lipoid thromboplastin as distinct factors with complementary functions.

1952 • 10 citations

Thrombokinase of the Blood as Trypsin-Like Enzyme

1962 • 10 citations

THE PURIFICATION OF PROTHROMBIN

1941 • 10 citations

Separation of the Antihemophilic Factor (F. VIII) from Fibrinogen With Thrombin and Manganese Chloride.

1966 • 10 citations

Activation of Prothrombin

1956 • 10 citations

THE EFFECTS OF ELLAGIC ACID ON THE COAGULATION MECHANISMS AND ON TRAUMATIC BLEEDING

1967 • 10 citations

Isolation of the Anti-Haemophilic Factor from Human Plasma

1956 • 10 citations

Blood Thromboplastin: Its Preparation and Properties

1959 • 10 citations

Die Plasma-Fraktion I nach Cohn - ihre Anwendung bei der Hämophilie, der Angiohämophilie und schweren Blutungen nach einer Antikoagulantienbehandlung

1959 • 9 citations

Conditions influencing the Stability of Human Antihæmophilic Factor

1962 • 9 citations

Autocatalysis in prothrombin activation

1962 • 9 citations

Functional Alteration in the Prothrombin Molecule

1962 • 9 citations

The Molecular Weight of Factor XII (Hageman Factor) Estimated with Ionizing Radiation

1965 • 9 citations

Studies on the Purification and Stability of Human Antihaemophilic Factor (Factor VIII)

1965 • 8 citations

PROTHROMBIN IN ENZYMOLOGY, THROMBOSIS AND HEMOPHILIA

1968 • 8 citations

Nature of an Accelerator of Prothrombin Activation Arising During Storage of Purified Prothrombin.

1952 • 8 citations

Separation of Factor VIII (Antihaemophilic Factor) Activity from Fibrinogen by Means of a Snake Venom

1965 • 8 citations

Peptides Attached to Thrombin: Their Influence on Proteolysis

1965 • 8 citations

Concept of a Common Protein Moiety, Containing Disulfide Bonds, in Prothrombin, Prothrombin Derivative (Autoprothrombin) and Thrombin

1955 • 8 citations

A Highly Active Material that Promotes Conversion of Prothrombokinase Complex.

1949 • 8 citations

Inactivation of Antihæmophilic Globulin by Thrombin

1957 • 8 citations

Studies on the Role of an Accelerator Factor in the Blood Clotting Mechanism

1956 • 7 citations

Purification of Human and Bovine Accelerin (Serum Accelerator Globulin) on an Anion Exchange Resin Column

1961 • 7 citations

Production of an Inactive Derivative of Purified Prothrombin by Means of Purified Thrombin.

1949 • 7 citations

Separation of Thrombin from Thrombokinase by Continuous Flow Paper Electrophoresis.

1959 • 7 citations

Thromboplastic Activity of Red Cells

1961 • 7 citations

Possible Relationships Between Clotting Factors in Vitro and Intravascular Clotting

1959 • 7 citations

INTERACTIONS OF PHOSPHOLIPIDS WITH LIPOPROTEINS, WITH SERUM AND ITS PROTEINS, AND WITH PROTEOLYTIC AND NONPROTEOLYTIC ENZYMES IN BLOOD CLOTTING*,†

1965 • 7 citations

Eine systematische Untersuchung über die Bedeutung der Lipoide für die Blutgerinnung

1953 • 7 citations

An Electrophoretic Study of Purified Thrombin.

1959 • 6 citations

Certain biochemical properties of human AHF (Factor 8) separated from fibrinogen with manganous chloride and thrombin.

1966 • 6 citations

CHRISTMAS FACTOR (IX) DEFECT IN A CASE OF HAEMORRHAGIC THROMBOCYTHAEMIA

1959 • 6 citations

FURTHER STUDIES ON THE PURIFICATION OF ANTITHROMBIN AND HEPARIN COFACTOR

1957 • 5 citations

Zur Charakterisierung der Antithrombokinasen

1962 • 5 citations

Role of Plasma Accelerator-Globulin and Serum Accelerator-Globulin in Conversion of Prothrombin

1958 • 5 citations

THE INACTIVATION OF ANTITHROMBIN BY ETHER: EVIDENCE AGAINST THE EXISTENCE OF ANTITHROMBIN IV

1965 • 5 citations

QUANTITATIVE CONCEPTS RELATED TO PROTHROMBIN AND AUTOPROTHROMBIN I ACTIVITY

1956 • 5 citations

Die Inaktivierung der Blutthrombokinase in Gegenwart von Prothrombin und Faktor VIII

1964 • 5 citations

Initiation of blood clotting and glass activation followed with a three-stage technique

1962 • 5 citations

Nature of the Blood Coagulation Mechanisms in SPCA Plasma

1955 • 5 citations

Antihæmophilic Globulin in Frozen Plasma

1963 • 5 citations

Physiology of blood coagulation: Advances, problems and present status

1968 • 4 citations

Formation of Blood Thrombokinase

1955 • 4 citations

Intermediate Reactions in Blood Coagulation

1953 • 4 citations

Initiation of blood clotting and glass activation followed with a three-stage technique

1962 • 4 citations

Ellagic acid-induced acceleration of intravascular clotting and thrombolysis.

1966 • 4 citations

Die Angriffspunkte des Sphingosins, eines physiologischen Hemmstoffes der Blutgerinnung

1957 • 4 citations

Die progressiv wirksamen Inhibitoren der Blutgerinnung nach Marcumar-Intoxikation

1963 • 4 citations

Zur Aktivierung der Anti-Blutthrombokinase bei der Gerinnung in vitro

1963 • 4 citations

Fundamental Function of Ac-globulin and Lipid in Blood Clotting

1963 • 4 citations

The Purification and Properties of Platelet Cofactor I (Factor VIII)¹

1963 • 3 citations

Bovine serum as a complement for the combined effects of thrombokinase and cephalin.

1952 • 3 citations

Isolation of Coagulation Factors by Continuous Flow Electrophoresis.

1959 • 3 citations

Preparation and Activity of Factor V from Small Quantities of Bovine Plasma

1968 • 3 citations

Purification of Ac-globulin

1964 • 3 citations

The employment of DEAF-cellulose columns on a “rejection” principle in the preparation of factor VII

1965 • 2 citations

[Inhibition of blood coagulation].

1951 • 2 citations

HAGEMAN FACTOR AND FIBRINOLYSIS

1966 • 2 citations

Stabilization of Factor VIII by Glycerol

1966 • 1 citations

[History of hemophilia].

1966 • 1 citations

STUDIES ON THE PURIFICATION OF THROMBOPLASTIC PLASMA COMPONENT (ANTIHEMOPHILIC SUBSTANCE) IN HUMAN BLOOD

1957 • 1 citations

Deleted Work

1955 • 0 citations

Cited By (0)

Loading...