The Blood Coagulation and Fibrinolytic Systems during Pregnancy

An Enzyme Cascade in the Blood Clotting Mechanism, and its Function as a Biochemical Amplifier

1964 • 1,099 citations

The histological localisation of fibrinolysin activator

1959 • 617 citations

THE MECHANISM OF CLOT DISSOLUTION BY PLASMIN*

1959 • 581 citations

THE MAINTENANCE OF A SUSTAINED THROMBOLYTIC STATE IN MAN. I. INDUCTION AND EFFECTS*

1959 • 243 citations

Abnormal Plasminogen-Plasmin System Activity (Fibrinolysis) in Patients with Hepatic Cirrhosis: Its Cause and Consequences*

1964 • 238 citations

PATHOGENESIS OF ATHEROSCLEROSIS

1949 • 215 citations

Albumin Density Gradient Separation and Washing of Platelets and the Study of Platelet Coagulant Activities

1972 • 211 citations

Antithrombin III, Antifactor Xa and Heparin

1970 • 200 citations

Coagulation and Fibrinolytic Systems in Pre-eclampsia and Eclampsia

1971 • 179 citations

Urokinase Inhibitor in Human Placenta

1968 • 167 citations

The Reaction between Bovine Brain Tissue Factor and Factors VII and X^*

1966 • 165 citations

LOCALIZATION OF FIBRINOLYTIC ACTIVITY IN TISSUES

1964 • 157 citations

Fibrinolytic Enzyme System and Pregnancy

1969 • 152 citations

Fibrinolytic Activity of Normal Urine

1947 • 142 citations

Increased Clotting Factors in Pregnancy

1961 • 139 citations

Platelet Function

1969 • 138 citations

Coagulation and Fibrinolytic Mechanisms During and After Normal Childbirth

1970 • 131 citations

Plasminogen activator activity in cultures from human tissues. An immunological and histochemical study

1969 • 127 citations

Changes in antihemophilic factor (AHF, factor 8) procoagulant activity and AHF-like antigen in normal pregnancy, and following exercise and pneumoencephalography.

1972 • 111 citations

STUDIES OF THE PLASMIN SYSTEM

1958 • 107 citations

Fibrin Degradation Products in Normal and Abnormal Pregnancy and Parturition

1969 • 103 citations

THE ULTRASTRUCTURE OF THE ARTERIAL SUPPLY OF THE HUMAN PLACENTA IN EARLY AND LATE PREGNANCY

1974 • 100 citations

Coagulation And Fibrinolytic Studies During Pregnancy¹

1967 • 90 citations

The Measurement of Heparin

1973 • 86 citations

Immunobiology of Fibrinogen. EMERGENCE OF NEOANTIGENIC EXPRESSIONS DURING PHYSIOLOGIC CLEAVAGE IN VITRO AND IN VIVO

1973 • 83 citations

FIBRINOLYTIC ACTIVITY IN THE ORGANISM

1959 • 81 citations

Formation of Prothrombin Converting Activity

1967 • 79 citations

Treatment Of Menorrhagia With An Antifibrinolytic Agent, Tranexamic Acid (Amca): A Double Blind Investigation

1967 • 78 citations

Haemostatic Mechanism in the Uterine Circulation during Placental Separation

1970 • 72 citations

Physicochemical Studies on Human Plasminogen (Profibrinolysin) and Plasmin (Fibrinolysin)

1958 • 71 citations

A Study of Coagulation Factor Levels in Women during Labour and in Their Newborn Infants

1966 • 70 citations

STUDIES ON A PROTEOLYTIC ENZYME IN HUMAN PLASMA. VII. A FATAL HEMORRHAGIC STATE ASSOCIATED WITH EXCESSIVE PLASMA PROTEOLYTIC ACTIVITY IN A PATIENT UNDERGOING SURGERY FOR CARCINOMA OF THE HEAD OF THE PANCREAS 1

1952 • 68 citations

Normal values of certain factors in the blood clotting mechanism in pregnancy

1964 • 62 citations

The Ultrastructure of Rabbit Blood Platelet Aggregates

1962 • 60 citations

Effect of urokinase antiserum on plasminogen activators: demonstration of immunologic dissimilarity between plasma plasminogen activator and urokinase

1968 • 59 citations

Plasminogen Activators in the Endometrium

1966 • 58 citations

CHANGES IN BLOOD COAGULATION DURING PREGNANCY.

1965 • 58 citations

Changes in maternal coagulation factors after intra-amniotic injection of hypertonic saline.

1971 • 56 citations

Human serum plasminogen antiactivator: its distinction from antiplasmin

1971 • 52 citations

Comparative Effects of Fibrinogen Degradation Fragments D and E on Coagulation

1972 • 48 citations

Cold Promoted Activation of Factor VII

1973 • 46 citations

Defibrination in Normal and Abnormal Parturition

1970 • 45 citations

Reduction in plasma factor 13 (fibrin stabilizing factor) concentration during pregnancy.

1969 • 45 citations

3. IDENTIFICATION AND PURIFICATION OF FIBRINOGEN DEGRADATION PRODUCTS PRODUCED BY PLASMIN: CONSIDERATIONS ON THE STRUCTURE OF FIBRINOGEN

1971 • 45 citations

ON THE RELATIONSHIP BETWEEN PLASMIN AND KININ*

1963 • 42 citations

The Fibrinolytic Agents in Saline Extracts of Human Tissues

1958 • 40 citations

Plasma thromboplastin antecedent (Factor XI) in the neonate

1965 • 40 citations

FIBRIN DEPOSITS ON THE SYNCYTIUM OF THE NORMAL HUMAN PLACENTA: EVIDENCE OF THEIR THROMBOGENIC ORIGIN

1968 • 40 citations

Coagulation Factors of the Newborn and His Mother

1973 • 39 citations

Fibrinolysis in Pre-eclamptic Toxaemia of Pregnancy

1969 • 37 citations

Separation and Characterization of Two Fibrinolytic Inhibitors from Human Placenta

1971 • 35 citations

Defibrinogenation after Intra-Amniotic Injection of Hypertonic Saline

1972 • 35 citations

Tissue Activator of the Fibrinolytic System in Placental Tissue

1962 • 28 citations

THE FIBRINOLYTIC ACTIVITY OF MENSTRUAL BLOOD

1956 • 27 citations

Studies on Fibrinolytic Inhibitors During Pregnancy

1971 • 25 citations

Observations on the clotting of menstrual blood and clot formation

1971 • 25 citations

The effects of Arvin on pregnancy in the mouse and the rabbit

1971 • 25 citations

Fibrinolytic Split Products in Serum and Urine in Pregnancy

1970 • 23 citations

40. THE BIOLOGICAL AND PHARMACOLOGICAL PROPERTIES OF SOME FIBRINOGEN DEGRADATION PRODUCTS*

1971 • 20 citations

Fibrinogen Turnover in Pregnancy

1969 • 19 citations

Coagulation disturbances in shock

1969 • 17 citations

THE BEHAVIOUR OF THE COAGULATION AND FIBRINOLYTIC MECHANISMS IN ABRUPTIO PLACENTAE

1969 • 15 citations

CRYOFIBRINOGENEMIA IN TOXEMIA OF PREGNANCY

1964 • 12 citations

41. THE CLINICAL SIGNIFICANCE OF FIBRINOGEN‐FIBRIN‐RELATED ANTIGEN IN SERUM

1971 • 11 citations

Further studies on an inhibitor of plasminogen activation in human serum. Release of the inhibitor during coagulation and thrombus formation.

1970 • 10 citations

37. ACTION OF FIBRINOGEN DEGRADATION PRODUCTS AND FIBRIN MONOMER SOLUBLE COMPLEXES ON PLATELET AGGREGATION

1971 • 10 citations

[Biochemistry of fibrinolysis].

1967 • 9 citations

The Fibrinolytic Enzyme System

1983 • 7 citations

Fibrinogen-fibrin degradation products in uterine and peripheral blood during Caesarean section.

1974 • 3 citations