The binding of Ca2+ ions to pig heart NAD+-isocitrate dehydrogenase and the 2-oxoglutarate dehydrogenase complex

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

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1975 • 20,446 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

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Critical Stability Constants

1975 • 2,263 citations

Applied Numerical Analysis.

1985 • 1,041 citations

Ca2+-induced hydrophobic site on calmodulin: Application for purification of calmodulin by phenyl-Sepharose affinity chromatography

1982 • 877 citations

Calmodulin

1982 • 771 citations

Binding of Diffusible Molecules by Macromolecules: Rapid Measurement by Rate of Dialysis

1969 • 517 citations

Neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium

1980 • 474 citations

Conformational transition accompanying the binding of calcium(2+) ion to the protein activator of 3',5'-cyclic adenosine monophosphate phosphodiesterase

1977 • 472 citations

Physicochemical properties of rat testis Ca2+-dependent regulator protein of cyclic nucleotide phosphodiesterase. Relationship of Ca2+-binding, conformational changes, and phosphodiesterase activity

1977 • 459 citations

Determination of citrate with citrate lyase

1966 • 438 citations

The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex

1979 • 431 citations

On the role of the calcium transport cycle in heart and other mammalian mitochondria

1980 • 375 citations

Relation between mitochondrial calcium transport and control of energy metabolism

1985 • 362 citations

Calcium ions and the regulation of NAD+-linked isocitrate dehydrogenase from the mitochondria of rat heart and other tissues

1978 • 359 citations

Effects of cations on affinity of calmodulin for calcium: ordered binding of calcium ions allows the specific activation of calmodulin-stimulated enzymes. Theoretical approach to study of multiple ligand binding to a macromolecule

1981 • 321 citations

Role of calcium ions in the regulation of intramitochondrial metabolism. Effects of Na+, Mg2+ and ruthenium red on the Ca2+-stimulated oxidation of oxoglutarate and on pyruvate dehydrogenase activity in intact rat heart mitochondria

1980 • 292 citations

Ca2+ transport by mammalian mitochondria and its role in hormone action

1985 • 242 citations

Calcium binding to complexes of calmodulin and calmodulin binding proteins

1985 • 152 citations

Regulation of NAD+-linked isocitrate dehydrogenase and 2-oxoglutarate dehydrogenase by Ca2+ ions within toluene-permeabilized rat heart mitochondria. Interactions with regulation by adenine nucleotides and NADH/NAD+ ratios

1988 • 124 citations

Purification and properties of pyruvate dehydrogenase phosphatase from bovine heart and kidney

1982 • 115 citations

Determination of the free-energy coupling for binding of calcium ion and troponin I to calmodulin

1982 • 110 citations

Chemical characterization of distinct subunits of pig heart DPN-specific isocitrate dehydrogenase.

1980 • 106 citations

The elementary reactions of the pig heart pyruvate dehydrogenase complex. A study of the inhibition by phosphorylation

1976 • 88 citations

Diphosphopyridine Nucleotide-linked Isocitrate Dehydrogenase from Bovine Heart

1970 • 84 citations

Sensitivity of pyruvate dehydrogenase phosphate phosphatase to magnesium ions. Similar effects of spermine and insulin

1986 • 84 citations

Regulation of bovine kidney .alpha.-ketoglutarate dehydrogenase complex by calcium ion and adenine nucleotides. Effects on S0.5 for .alpha.-ketoglutarate

1981 • 69 citations

Liver mitochondrial pyrophosphate concentration is increased by Ca2+ and regulates the intramitochondrial volume and adenine nucleotide content

1987 • 68 citations

New devices for flow dialysis and ultrafiltration for the study of protein-ligand interactions

1978 • 56 citations

Inhibition of bovine kidney .alpha.-ketoglutarate dehydrogenase complex by reduced nicotinamide adenine dinucleotide in the presence or absence of calcium ion and effect of adenosine 5'-diphosphate on reduced nicotinamide adenine dinucleotide inhibition

1981 • 53 citations

Action of Magnesium Ion on Diphosphopyridine Nucleotide-linked Isocitrate Dehydrogenase from Bovine Heart

1974 • 51 citations

Binding of ligands to half of subunits of NAD-dependent isocitrate dehydrogenase from pig heart. Binding of manganous ion, isocitrate, ADP and NAD.

1981 • 51 citations

Separation, recombination, and characterization of dissimilar subunits of the DPN-dependent isocitrate dehydrogenase from pig heart.

1983 • 38 citations

Re-evaluation of molecular weight of pig heart NAD-specific isocitrate dehydrogenase.

1981 • 38 citations

Structure, assembly and function of mammalian alpha-keto acid dehydrogenase complexes.

1976 • 36 citations

Effect of micromolar Ca2+ on NADH inhibition of bovine kidney ?-ketoglutarate dehydrogenase complex and possible role of Ca2+ in signal amplification

1980 • 33 citations

Evidence that adrenaline activates key oxidative enzymes in rat liver by increasing intramitochondrial [Ca²⁺]

1985 • 33 citations

A new solid-phase chelator with high affinity and selectivity for calcium: Parvalbumin-polyacrylamide

1977 • 31 citations

Ligand binding to macromolecules: Determination of binding parameters by combined use of ligand buffers and flow dialysis; application to calcium-binding proteins

1980 • 27 citations

Role of Manganous Ion in the Kinetics of Pig-Heart NAD-Specific Isocitrate Dehydrogenase

1974 • 25 citations

The Activation of Ox‐Brain NAD⁺‐Dependent Isocitrate Dehydrogenase by Magnesium Ions

1981 • 21 citations

Rapid purification of pig heart NAD+-isocitrate dehydrogenase. Studies on the regulation of activity by Ca2+, adenine nucleotides, Mg2+ and other metal ions

1989 • 21 citations

Studies on the specific activity of [γ-32P]ATP in adipose and other tissue preparations incubated with medium containing [32P]phosphate

1986 • 20 citations

Activity associated with individual subunits of pig heart NAD-specific isocitrate dehydrogenase

1982 • 10 citations

The role of dissimilar subunits of NAD-specific isocitrate dehydrogenase from pig heart. Evaluation using affinity labeling.

1984 • 7 citations