The Human Leukemia Cell Line HL-60 as a Cell Culture Model To Study Neutrophil Functions and Inflammatory Cell Responses
Data up to Jan 2025
Total Citations Per Year
Abstract
References (32)
Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells
1989 • 4,279 citations
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
1988 • 2,380 citations
Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture
1977 • 2,134 citations
Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML
1991 • 1,463 citations
The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus
1990 • 1,349 citations
The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression
1987 • 1,180 citations
Quantitative Nitroblue Tetrazolium Test in Chronic Granulomatous Disease
1968 • 894 citations
NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)
1991 • 884 citations
Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line
1982 • 630 citations
Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.
1982 • 570 citations
Transphosphatidylation by Phospholipase D
1967 • 563 citations
Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells.
1985 • 414 citations
The HL-60 transforming sequence: A ras oncogene coexisting with altered myc genes in hematopoietic tumors
1983 • 341 citations
A simple method for the solubilisation of reduced NBT, and its use as a colorimetric assay for activation of human macrophages by γ-interferon
1985 • 327 citations
HL-60 cell line was derived from a patient with FAB-M2 and not FAB-M3
1988 • 233 citations
Expression and regulation of myeloid-specific genes in normal and leukemic myeloid cells
1991 • 178 citations
Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene.
1990 • 177 citations
Replacement of serum by insulin and transferrin supports growth and differentiation of the human promyelocytic cell line, HL-60
1980 • 170 citations
A Simplified Method for the Preparation of Transcriptionally Active Liver Nuclear Extracts
1990 • 134 citations
Ca2 +‐mobilizing hormones elicit phosphatidylethanol accumulation via phospholipase D activation
1987 • 130 citations
Intracellular location of T200 and Mo1 glycoproteins in human neutrophils.
1988 • 102 citations
Leukemia cell lines: In vitro models for the study of acute promyelocytic leukemia
1995 • 95 citations
Early and Selective Induction of Apoptosis in Human Leukemic Cells by the Alkyl-Lysophospholipid ET-18-OCH3
1993 • 89 citations
Inhibition of N‐linked glycosylation induces early apoptosis in human promyelocytic HL‐60 cells
1995 • 73 citations
Isolation and characterization of an apoptosis-resistant variant of human leukemia HL-60 cells that has switched expression from Bcl-2 to Bcl-xL.
1996 • 72 citations
Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes
1993 • 64 citations
Involvement of phospholipase D in the activation of transcription factor AP-1 in human T lymphoid Jurkat cells.
1994 • 60 citations
The type B receptor for tumor necrosis factor-alpha mediates DNA fragmentation in HL-60 and U937 cells and differentiation in HL-60 cells
1992 • 49 citations
Expression of c-jun, jun B and jun D proto-oncogenes in human peripheral-blood granulocytes
1991 • 36 citations
Enhancement of human neutrophil functions by a monoclonal antibody directed against a 19-kDa antigen.
1992 • 27 citations
Uncoupled changes in the expression of the jun family members during myeloid cell differentiation
1991 • 17 citations
Dexamethasone modifies the functional responses of the granulocytic differentiating HL-60 cells
1994 • 17 citations