Autologous activated natural killer cells suppress primitive chronic myelogenous leukemia progenitors in long-term culture

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1

1989 • 837 citations

Direct contact between human primitive hematopoietic progenitors and bone marrow stroma is not required for long-term in vitro hematopoiesis

1992 • 245 citations

Selection of benign primitive hematopoietic progenitors in chronic myelogenous leukemia on the basis of HLA-DR antigen expression

1992 • 202 citations

Inhibition of in vitro granulopoiesis by autologous allogeneic human NK cells.

1982 • 199 citations

Autologous transplants for chronic myelogenous leukaemia: results from eight transplant groups

1994 • 178 citations

The generation of human natural killer cells from CD34+/DR- primitive progenitors in long-term bone marrow culture

1992 • 167 citations

Effect of low-dose interleukin-2 on disease relapse after T-cell- depleted allogeneic bone marrow transplantation

1994 • 152 citations

Anti-leukemia potential of interleukin-2 activated natural killer cells after bone marrow transplantation for chronic myelogenous leukemia

1990 • 150 citations

The leukocyte integrins

1989 • 135 citations

Natural killer cells suppress human erythroid stem cell proliferation in vitro

1984 • 122 citations

Role of monocytes in the expansion of human activated natural killer cells

1992 • 118 citations

Inhibition of bone marrow colony formation by human natural killer cells and by natural killer cell-derived colony-inhibiting activity.

1985 • 115 citations

Autologous blood stem cell transplantation for chronic granulocytic leukaemia in transformation: a report of 47 cases

1991 • 94 citations

In vitro regulation of human hematopoiesis by natural killer cells: analysis at a clonal level

1987 • 74 citations

Identification of BCR/ABL-negative primitive hematopoietic progenitor cells within chronic myeloid leukemia marrow

1993 • 66 citations

Treatment of marrow stroma with interferon-alpha restores normal beta 1 integrin-dependent adhesion of chronic myelogenous leukemia hematopoietic progenitors. Role of MIP-1 alpha.

1995 • 62 citations

Therapy of Acute-Phase Chronic Myelogenous Leukemia with Intensive Chemotherapy, Blood Cell Autotransplantation and Cyclosporine A

1992 • 61 citations

Bone marrow transplantation with interleukin-2-activated bone marrow followed by interleukin-2 therapy for acute myeloid leukemia in mice

1990 • 61 citations

Autologous transplantation for CML using marrow treated ex vivo with recombinant human interferon gamma.

1990 • 60 citations

Human natural killer cell expansion is regulated by thrombospondin- mediated activation of transforming growth factor-beta 1 and independent accessory cell-derived contact and soluble factors

1996 • 58 citations

Diminished A-LAK cytotoxicity and proliferation accompany disease progression in chronic myelogenous leukemia

1990 • 56 citations

Benign marrow progenitors are enriched in the CD34+/HLA-DRlo population but not in the CD34+/CD38lo population in chronic myeloid leukemia: an analysis using interphase fluorescence in situ hybridization

1995 • 54 citations

Diffusible factors from the murine cell line M2-10B4 support human in vitro hematopoiesis.

1994 • 46 citations

Large scale ex vivo expansion and activation of human natural killer cells for autologous therapy.

1994 • 45 citations

Lymphokine-activated killer cells selectively kill tumor cells in bone marrow without compromising bone marrow stem cell function in vitro

1989 • 43 citations

Adherent lymphokine-activated killer cells in chronic myelogenous leukemia: a benign cell population with potent cytotoxic activity

1989 • 43 citations

CD34+/CD33- cells reselected from macrophage inflammatory protein 1 alpha+interleukin-3--supplemented "stroma-noncontact" cultures are highly enriched for long-term bone marrow culture initiating cells

1994 • 41 citations

Effect of lymphokine-activated killer cell fraction on the development of human hematopoietic progenitor cells.

1988 • 41 citations

Detection of breakpoint cluster region- negative and nonclonal hematopoiesis in vitro and in vivo after transplantation of cells selected in cultures of chronic myeloid leukemia marrow

1990 • 40 citations

Natural Killer Cell Proliferation Is Dependent on Human Serum and Markedly Increased Utilizing an Enriched Supplemented Basal Medium

1995 • 38 citations

Modulation of in vitro myelopoiesis by LGL: different effects on early and late progenitor cells.

1986 • 37 citations

The effects of recombinant interleukin 2-activated natural killer cells on autologous peripheral blood hematopoietic progenitors.

1988 • 34 citations

Selective generation of erythroid burst-promoting activity by recombinant interleukin 2-stimulated human T lymphocytes and natural killer cells

1988 • 29 citations

Potent graft antitumor effect in natural killer-resistant disseminated tumors by transplantation of interleukin 2-activated syngeneic bone marrow in mice.

1989 • 29 citations

Design and validation of a clinically applicable culture procedure for the generation of interleukin-2 activated natural killer cells in human bone marrow autografts.

1993 • 25 citations

Adherent lymphokine-activated killer cells suppress autologous human normal bone marrow progenitors

1991 • 23 citations

Immunotherapy with autologous bone-marrow transplantation: rationale and results.

1994 • 22 citations

Interleukin-2 in therapy of hematologic malignancies [editorial; comment]

1994 • 22 citations

Hematopoiesis in vitro coexists with natural killer lymphocytes

1989 • 17 citations

Therapy for chronic myelogenous leukemia with marrow transplantation

1993 • 13 citations

Effect of cortisol on the native and in vitro induced non-MHC restricted cytotoxicity of large granular lymphocytes.

1988 • 11 citations

Origin and function of adherent lymphokine activated killer cells in patients with chronic myeloid leukaemia who relapse following bone marrow transplantation

1991 • 10 citations

Expansion and Activation of Human Natural Killer Cells for Autologous Therapy

1994 • 6 citations