Cell Cultures as Model Systems for Studying the Biochemistry of Differentiated Functions of Nerve Cells

Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo

1952 • 2,384 citations

Differentiated Rat Glial Cell Strain in Tissue Culture

1968 • 1,480 citations

The influence of potassium and chloride ions on the membrane potential of single muscle fibres

1959 • 1,458 citations

Tetrodotoxin Blockage of Sodium Conductance Increase in Lobster Giant Axons

1964 • 1,065 citations

Effects of calcium ions and local anaesthetics on electrical properties of Purkinje fibres

1955 • 708 citations

Neurotransmitter Synthesis by Neuroblastoma Clones

1972 • 695 citations

The ionic requirements for the production of action potentials in crustacean muscle fibres

1958 • 666 citations

THE ACTION OF CERTAIN ESTERS AND ETHERS OF CHOLINE, AND THEIR RELATION TO MUSCARINE

1914 • 604 citations

The Selective Inhibition of Delayed Potassium Currents in Nerve by Tetraethylammonium Ion

1967 • 490 citations

ESTABLISHMENT OF FUNCTIONAL CLONAL LINES OF NEURONS FROM MOUSE NEUROBLASTOMA

1969 • 486 citations

Definition of a continuous human cell line derived from neuroblastoma.

1970 • 480 citations

Regulation of Axon Formation by Clonal Lines of a Neural Tumor

1970 • 480 citations

Anomalous Rectification in the Squid Giant Axon Injected with Tetraethylammonium Chloride

1965 • 439 citations

Acetylcholine Receptors of Muscle Grown In Vitro

1972 • 329 citations

The use of drug-resistant markers to study the hybridization of mouse fibroblasts

1966 • 326 citations

DEMONSTRATION OF TWO STABLE POTENTIAL STATES IN THE SQUID GIANT AXON UNDER TETRAETHYLAMMONIUM CHLORIDE

1957 • 323 citations

In vitro DIFFERENTIATION OF A MOUSE NEUROBLASTOMA

1969 • 306 citations

The Mode of Neuromuscular Block Caused by Acetylcholine, Nicotine, Decamethonium and Suecinylcholine¹

1955 • 283 citations

Depolarization of the motor end‐plate by decamethonium and acetylcholine

1951 • 246 citations

Effect of Catecholamines on the Adenosine 3′:5′-Cyclic Monophosphate Concentrations of Clonal Satellite Cells of Neurons

1971 • 245 citations

Effects of blocking sulfhydryl groups and of reducing disulfide bonds on the acetylcholine-activated permeability system of the electroplax

1966 • 237 citations

Regulation of Acetylcholinesterase in Neuroblastoma Cells

1970 • 225 citations

Graded and All-or-None Electrogenesis in Arthropod Muscle

1961 • 214 citations

Genetic Dissection of Neural Properties using Somatic Cell Hybrids

1972 • 178 citations

NEURONAL TUMOR CELLS WITH EXCITABLE MEMBRANES GROWN in vitro

1969 • 171 citations

Regulation of Adenosine 3′,5′-Cyclic Monophosphate Metabolism in Cultured Neuroblastoma Cells

1971 • 168 citations

Regulation of Adenosine 3′:5′-Cyclic Monophosphate Concentration in Cultured Human Astrocytoma Cells by Catecholamines and Histamine

1971 • 168 citations

The action of d‐tubocurarine and of decamethonium on respiratory and other muscles in the cat

1951 • 168 citations

Biochemically Differentiated Neoplastic Clone of Schwann Cells

1972 • 165 citations

High activity of choline acetyltransferase induced in neuroblastoma X glia hybrid cells

1974 • 164 citations

Tetrodotoxin and Manganese Ions: Effects on Electrical Activity and Tension in Taenia Coli of Guinea Pig

1966 • 161 citations

Acetylcholine Sensitivity and Distribution on Mouse Neuroblastoma Cells

1970 • 154 citations

SPECIFIC EXCITABILITY OF THE ENDPLATE REGION IN NORMAL AND DENERVATED MUSCLE

1943 • 152 citations

Prostaglandin production by neuroblastoma, glioma and fibroblast cell lines; Stimulation by N⁶, O²′‐dibutyryl adenosine 3′:5′‐cyclic monophosphate

1973 • 101 citations

EFFECT OF TETRODOTOXIN ON SMOOTH MUSCLE CELLS OF THE GUINEA‐PIG TAENIA COLI

1966 • 87 citations

ELECTRICAL PHENOMENA IN NERVE

1949 • 85 citations

Acetylcholine receptors: topographic distribution and pharmacological properties of two receptor types on a single molluscan neurone

1972 • 81 citations

Pharmacology of 1,1-dimethyl-4-phenylpiperazinium iodide, a ganglion stimulating agent.

1951 • 76 citations

Responses of neuroblastoma cells to iontophoretically applied acetylcholine

1971 • 73 citations

Accumulation of Adenosine 3′:5′-Cyclic Monophosphate in Clonal Glial Cells: Labeling of Intracellular Adenine Nucleotides with Radioactive Adenine

1972 • 66 citations

Die Wirkung von Tetra�thylammoniumchlorid auf den einzelnen Ranvierschen Schn�rring

1966 • 63 citations

[The effect of tetraethylammonium chloride on single Ranvier's nodes].

1966 • 54 citations

Influence of Noradrenalin, Prostaglandin E₁and Inhibitors of Phosphodiesterase Activity on Levels of the Cyclic Adenosine 3′:5′-monophosphate in Somatic Cell Hybrids

1973 • 50 citations

The effect of cations on the electrical properties of the smooth muscle cells of the guinea‐pig vas deferens

1967 • 50 citations

Tetrodotoxin and Cobalt Blockade of Neuroblastoma Action Potentials

1973 • 50 citations

Dopamine‐β‐hydroxylase activity in cholinergic neuroblastoma × glioma hybrid cells; increase of activity by N⁶,O²′‐dibutyryl adenosine 3′: 5′‐cyclic monophosphate

1974 • 49 citations

Dopamine-β-Hydroxylase Activity in Mouse Neuroblastoma Tumors and in Cell Cultures

1972 • 47 citations

Stimulation by prostaglandin E₁ of adenosine 3′:5′‐cyclic monophosphate formation in neuroblastoma cells in the presence of phosphodiesterase inhibitors

1973 • 45 citations

Tetrodotoxin resistant action potentials in denervated rat skeletal muscle

1970 • 44 citations

Differential assay for choline acetyltransferase

1974 • 43 citations

The effect of quaternary ammonium ions on crustacean nerve fibres

1953 • 40 citations

Adenyl cyclase, phosphodiesterase and cyclic AMP dependent protein kinase of malignant glial cells in culture

1971 • 38 citations

A STUDY OF THE INTERACTION BETWEEN NEUROMUSCULAR BLOCKING AGENTS AND ACETYLCHOLINE AT THE MAMMALIAN MOTOR END‐PLATE

1958 • 33 citations

Affinity oxidation of the reduced acetylcholine receptor

1970 • 26 citations

DRUGS AFFECTING PARASYMPATHETIC NERVES

1937 • 24 citations

On the effect of certain quaternary ammonium ions upon frog nerve. Part II

1949 • 14 citations