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Recent Understandings Toward Coronavirus Disease 2019 (COVID-19): From Bench to Bedside

Data up to Jan 2025

Published2020
Citations44
References103

Total Citations Per Year

Abstract

References (103)

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

2020 • 49,017 citations

A Novel Coronavirus from Patients with Pneumonia in China, 2019

2020 • 28,565 citations

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

2020 • 27,450 citations

A pneumonia outbreak associated with a new coronavirus of probable bat origin

2020 • 21,785 citations

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

2020 • 21,638 citations

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

2020 • 19,727 citations

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

2020 • 17,489 citations

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia

2020 • 17,090 citations

A new coronavirus associated with human respiratory disease in China

2020 • 12,053 citations

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

2020 • 12,050 citations

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

2020 • 9,089 citations

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

2020 • 8,517 citations

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

2020 • 8,060 citations

The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application

2020 • 6,265 citations

First Case of 2019 Novel Coronavirus in the United States

2020 • 6,200 citations

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

2020 • 6,064 citations

Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis

2004 • 5,665 citations

Detection of SARS-CoV-2 in Different Types of Clinical Specimens

2020 • 5,204 citations

Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study

2020 • 4,741 citations

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

2020 • 4,344 citations

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

2020 • 4,029 citations

Structural basis of receptor recognition by SARS-CoV-2

2020 • 3,783 citations

Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study

2020 • 3,689 citations

Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records

2020 • 3,503 citations

Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR

2020 • 3,453 citations

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

2020 • 2,939 citations

Emerging coronaviruses: Genome structure, replication, and pathogenesis

2020 • 2,904 citations

Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses

2016 • 2,900 citations

The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China

2020 • 2,887 citations

An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study

2020 • 2,292 citations

A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)

2020 • 2,273 citations

Mitigate the effects of home confinement on children during the COVID-19 outbreak

2020 • 2,028 citations

Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury

2020 • 2,017 citations

Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy

2020 • 2,000 citations

Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins

2020 • 1,920 citations

Consistent Detection of 2019 Novel Coronavirus in Saliva

2020 • 1,905 citations

Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19

2020 • 1,657 citations

A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV

2020 • 1,598 citations

Structure of the RNA-dependent RNA polymerase from COVID-19 virus

2020 • 1,572 citations

Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20–28 January 2020

2020 • 1,545 citations

Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease

2020 • 1,447 citations

Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data

2020 • 1,426 citations

Baricitinib as potential treatment for 2019-nCoV acute respiratory disease

2020 • 1,389 citations

Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group

2020 • 1,363 citations

Real estimates of mortality following COVID-19 infection

2020 • 1,316 citations

Middle East respiratory syndrome

2015 • 1,243 citations

Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know

2020 • 1,187 citations

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

2020 • 1,173 citations

Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State

2020 • 1,125 citations

Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease

2020 • 1,113 citations

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

2020 • 1,073 citations

A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2

2020 • 1,034 citations

Practical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patients

2020 • 1,025 citations

Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial

2020 • 1,021 citations

Proteomics of SARS-CoV-2-infected host cells reveals therapy targets

2020 • 1,020 citations

Can we contain the COVID-19 outbreak with the same measures as for SARS?

2020 • 977 citations

The convalescent sera option for containing COVID-19

2020 • 949 citations

Coronavirus Genomics and Bioinformatics Analysis

2010 • 902 citations

Coronavirus Pathogenesis

2011 • 887 citations

Anti–spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection

2019 • 874 citations

COVID-19 control in China during mass population movements at New Year

2020 • 847 citations

Vaccination and herd immunity to infectious diseases

1985 • 768 citations

Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China

2020 • 722 citations

Outcomes of Hydroxychloroquine Usage in United States Veterans Hospitalized with COVID-19

2020 • 595 citations

SARS: epidemiology

2003 • 561 citations

Indirect Virus Transmission in Cluster of COVID-19 Cases, Wenzhou, China, 2020

2020 • 543 citations

Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? A Comprehensive Evaluation of Clinical and Basic Evidence

2020 • 523 citations

Human Leukocyte Antigen Susceptibility Map for Severe Acute Respiratory Syndrome Coronavirus 2

2020 • 518 citations

Are high-performing health systems resilient against the COVID-19 epidemic?

2020 • 503 citations

Middle East respiratory syndrome

2020 • 444 citations

Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data

2020 • 438 citations

Interrupting transmission of COVID-19: lessons from containment efforts in Singapore

2020 • 409 citations

Initial Public Health Response and Interim Clinical Guidance for the 2019 Novel Coronavirus Outbreak — United States, December 31, 2019–February 4, 2020

2020 • 398 citations

Lack of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, China

2020 • 381 citations

Taking the right measures to control COVID-19

2020 • 352 citations

Chinese expert consensus on the perinatal and neonatal management for the prevention and control of the 2019 novel coronavirus infection (First edition)

2020 • 343 citations

Case-Fatality Risk Estimates for COVID-19 Calculated by Using a Lag Time for Fatality

2020 • 337 citations

Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19

2020 • 328 citations

A distinct name is needed for the new coronavirus

2020 • 326 citations

Effect of SARS-CoV-2 infection upon male gonadal function: A single center-based study

2020 • 272 citations

Guidelines for pregnant women with suspected SARS-CoV-2 infection

2020 • 255 citations

HERD IMMUNITY: BASIC CONCEPT AND RELEVANCE TO PUBLIC HEALTH IMMUNIZATION PRACTICES1

1971 • 251 citations

Isolation and Characterization of 2019-nCoV-like Coronavirus from Malayan Pangolins

2020 • 217 citations

Identification of 2019-nCoV related coronaviruses in Malayan pangolins in southern China

2020 • 208 citations

COVID‐19 Presents High Risk to Older Persons

2020 • 177 citations

COVID‐19 vaginal delivery – A case report

2020 • 146 citations

[Expert consensus on the use of corticosteroid in patients with 2019-nCoV pneumonia].

2020 • 145 citations

Is COVID-19 an Endothelial Disease? Clinical and Basic Evidence

2020 • 126 citations

Middle East respiratory syndrome

2020 • 112 citations

Cyclic exit strategies to suppress COVID-19 and allow economic activity

2020 • 111 citations

Early containment strategies and core measures for prevention and control of novel coronavirus pneumonia in China

2020 • 88 citations

Human leukocyte antigen susceptibility map for SARS-CoV-2

2020 • 70 citations

An Extensive Meta-Metagenomic Search Identifies SARS-CoV-2-Homologous Sequences in Pangolin Lung Viromes

2020 • 60 citations

The global population of SARS-CoV-2 is composed of six major subtypes

2020 • 58 citations

Data analysis and modeling of the evolution of COVID-19 in Brazil

2020 • 54 citations

A Conceptual Discussion About the Basic Reproduction Number of Severe Acute Respiratory Syndrome Coronavirus 2 in Healthcare Settings

2020 • 41 citations

Identification of a pangolin niche for a 2019-nCoV-like coronavirus through an extensive meta-metagenomic search

2020 • 32 citations

[Diagnosis and clinical management of 2019 novel coronavirus infection: an operational recommendation of Peking Union Medical College Hospital (V2.0)].

2020 • 23 citations

The global population of SARS-CoV-2 is composed of six major subtypes

2020 • 21 citations

ESTIMATING R0 OF SARS-COV-2 IN HEALTHCARE SETTINGS

2020 • 10 citations

NK cells join the anti-cancer armory

2020 • 6 citations

Modest effects of contact reduction measures on the reproduction number of SARS-CoV-2 in the most affected European countries and the US

2020 • 2 citations

Determination of daily reproduction numbers of SARS-CoV2 based on death cases suggests more rapid initial spread in Italy and the United States

2020 • 1 citations

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Recent Understandings Toward Coronavirus Disease 2019 (COVID-19): From Bench to Bedside (2020) – Frontiers in Cell and Developmental Biology | Metascience Observatory Explorer