Autosomal Dominant Polycystic Kidney Disease

A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16

1985 • 715 citations

Factors affecting the progression of renal disease in autosomal-dominant polycystic kidney disease

1992 • 487 citations

Bilateral polycystic disease of the kidneys; a follow-up of two hundred and eighty-four patients and their families.

1957 • 411 citations

The Renin–Angiotensin–Aldosterone System and Autosomal Dominant Polycystic Kidney Disease

1990 • 391 citations

Epidemiology of Adult Polycystic Kidney Disease, Olmsted County, Minnesota: 1935–1980

1983 • 375 citations

The Diagnosis and Prognosis of Autosomal Dominant Polycystic Kidney Disease

1990 • 356 citations

Intracranial Aneurysms in Autosomal Dominant Polycystic Kidney Disease

1992 • 333 citations

Cyst formation and growth in autosomal dominant polycystic kidney disease

1987 • 327 citations

Diverticular Disease of the Colon

1980 • 306 citations

Evaluation of the electroinjection method for introducing proteins into living cells

1991 • 303 citations

Risk factors for the development of hepatic cysts in autosomal dominant polycystic kidney disease

1990 • 288 citations

Autosomal Dominant Polycystic Kidney Disease—More Than a Renal Disease

1990 • 259 citations

Linkage Heterogeneity of Autosomal Dominant Polycystic Kidney Disease

1988 • 227 citations

Echocardiographic Findings in Autosomal Dominant Polycystic Kidney Disease

1988 • 220 citations

Renal structure and hypertension in autosomal dominant polycystic kidney disease

1990 • 218 citations

Diverticular Disease in Patients with Chronic Renal Failure Due to Polycystic Kidney Disease

1980 • 212 citations

c-myc as an inducer of polycystic kidney disease in transgenic mice

1991 • 210 citations

Polycystic Kidney Disease: Prospective Analysis of Nonazotemic Patients and Family Members

1984 • 188 citations

Value of magnetic resonance angiography for the detection of intracranial aneurysms in autosomal dominant polycystic kidney disease.

1993 • 177 citations

Characteristics of very early onset autosomal dominant polycystic kidney disease.

1993 • 175 citations

Hypertension in autosomal dominant polycystic kidney disease

1988 • 170 citations

Age at clinical onset and at ultrasonographic detection of adult polycystic kidney disease: Data for genetic counselling

1984 • 167 citations

Renal epithelial cyst formation and enlargement in vitro: dependence on cAMP.

1989 • 164 citations

Association of Hypokalemia, Aldosteronism, and Renal Cysts

1990 • 160 citations

Cardiovascular Abnormalities Associated with Adult Polycystic Kidney Disease

1984 • 159 citations

Autosomal dominant polycystic kidney disease in childhood: A longitudinal study

1987 • 153 citations

Hereditary polycystic kidney disease (adult form): A microdissection study of two cases at an early stage of the disease

1978 • 146 citations

A SECOND GENETIC LOCUS FOR AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE

1988 • 143 citations

Hepatic Cyst Infection in Autosomal Dominant Polycystic Kidney Disease

1990 • 141 citations

Prognosis of adult onset polycystic kidney disease re-evaluated

1984 • 140 citations

Ultrastructure and function of cysts from human adult polycystic kidneys

1980 • 138 citations

Liver cysts in patients with autosomal dominant polycystic kidney disease

1980 • 137 citations

Dynamics of erythropoiesis following renal transplantation

1987 • 129 citations

The Association of Nephrolithiasis and Autosomal Dominant Polycystic Kidney Disease

1988 • 128 citations

The clinical utility of renal concentrating capacity in polycystic kidney disease

1989 • 128 citations

Erythropoietin in polycystic kidneys.

1989 • 127 citations

Clinical Profiles of Gross Hematuria in Autosomal Dominant Polycystic Kidney Disease

1992 • 122 citations

PRENATAL DIAGNOSIS OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE WITH A DNA PROBE

1986 • 121 citations

The anatomy of the renin-secreting cell in adult polycystic kidney disease

1988 • 121 citations

Renal epithelial fluid secretion and cyst growth: the role of cyclic AMP

1989 • 120 citations

Polypoid and papillary epithelial hyperplasia: A potential cause of ductal obstruction in adult polycystic disease

1979 • 120 citations

Renal infection in autosomal dominant polycystic kidney disease

1987 • 116 citations

The Secretion of Fluid by Renal Cysts from Patients with Autosomal Dominant Polycystic Kidney Disease

1993 • 116 citations

Functional similarities of hepatic cystic and biliary epithelium: Studies of fluid constituents andin vivo secretion in response to secretin

1990 • 115 citations

Glomerulosclerosis and renal cysts in mice transgenic for the early region of SV40

1987 • 114 citations

Polycystic kidney disease and intracranial aneurysms

1983 • 113 citations

The renal lesions of tuberous sclerosis.

1986 • 112 citations

Is Gender a Determinant for Evolution of Renal Failure? A Study in Autosomal Dominant Polycystic Kidney Disease

1989 • 112 citations

Renal, cardiovascular and hormonal characteristics of young adults with autosomal dominant polycystic kidney disease

1991 • 111 citations

Cytokines in fluids from polycystic kidneys

1991 • 110 citations

Cyst decompression surgery for autosomal dominant polycystic kidney disease.

1992 • 110 citations

Treatment of Highly Symptomatic Polycystic Liver Disease

1990 • 110 citations

Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease.

1992 • 108 citations

THE ASSOCIATION OF POLYCYSTIC KIDNEYS WITH INTRACRANIAL ANEURYSMS AND OTHER RELATED DISORDERS

1953 • 108 citations

Renal Epithelial Hyperplastic and Neoplastic Proliferation in Autosomal Dominant Polycystic Kidney Disease

1987 • 107 citations

Macropuncture study of polycystic disease in adult human kidneys

1980 • 107 citations

A Follow‐up Examination of 138 Cases of Subarachnoid Hemorrhage¹

1950 • 107 citations

Polycystic liver disease: Quantitation of parenchymal and cyst volumes from computed tomography images and clinical correlates of hepatic cysts

1988 • 107 citations

Reduction of Cyst Volume for Symptomatic Management of Autosomal Dominant Polycystic Kidney Disease

1987 • 106 citations

Elevated blood pressure profile and left ventricular mass in children and young adults with autosomal dominant polycystic kidney disease.

1993 • 105 citations

Von Hippel-Lindau's Disease

1961 • 102 citations

Diagnosis of autosomal dominant polycystic kidney disease in utero and in the young infant.

1987 • 102 citations

Altered mRNA expression of basement membrane components in a murine model of polycystic kidney disease.

1988 • 101 citations

Abnormal extracellular matrix and excessive growth of human adult polycystic kidney disease epithelia

1992 • 99 citations

Autosomal dominant polycystic kidney disease: symptoms and clinical findings.

1984 • 95 citations

Renal cell carcinoma in von hippel-lindau syndrome

1987 • 95 citations

In vitro formation and expansion of cysts derived from human renal cortex epithelial cells

1992 • 94 citations

Composition of Fluid in Twelve Cysts of a Polycystic Kidney

1969 • 83 citations

Serum Immunoreactive Erythropoietin Levels in Patients with Polycystic Kidney Disease as Compared with Other Hemodialysis Patients

1985 • 82 citations

Adult Dominant Polycystic Kidney Disease – Clinical Problems

1988 • 82 citations

The liver in autosomal dominant polycystic kidney disease. Implications for pathogenesis.

1990 • 80 citations

Reversible changes of tubular cell and basement membrane in drug-induced renal cystic disease

1984 • 80 citations

The cystic renal lesion in tuberous sclerosis

1980 • 79 citations

Attitudes of at-risk and affected individuals regarding presymptomatic testing for autosomal dominant polycystic kidney disease

1990 • 76 citations

Acquired cystic disease: mechanisms and manifestations.

1991 • 73 citations

Effects of angiotensin converting enzyme inhibition in adult polycystic kidney disease

1992 • 73 citations

Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro.

1992 • 73 citations

Expression of Differentiation Antigens and Growth-Related Genes in Normal Kidney, Autosomal Dominant Polycystic Kidney Disease, and Renal Cell Carcinoma

1992 • 73 citations

Tubulocystic epithelium

1991 • 68 citations

The Role of Computed Tomography in the Evaluation of Adult Polycystic Kidney Disease

1981 • 66 citations

Cyst Fluid Antibiotic Concentrations in Autosomal-Dominant Polycystic Kidney Disease

1985 • 63 citations

Intrafamilial Phenotypic Expression of Autosomal Dominant Polycystic Kidney Disease

1992 • 62 citations

Renal cysts, erythropoietin and polycythemia

1963 • 61 citations

Fluid secretion in arachnoid cysts as a clue to cerebro-spinal fluid absorption at the arachnoid granulation

1986 • 57 citations

Ciprofloxacin activity in cyst fluid from polycystic kidneys

1988 • 54 citations

Urological Management of Patients with Von Hippel-Lindau’s Disease

1986 • 54 citations

Cyst fluid antibiotic concentrations in polycystic kidney disease: Differences between proximal and distal cysts

1981 • 53 citations

Hypertension of Polycystic Kidney Disease: Mechanisms and Hemodynamic Alterations

1985 • 53 citations

Polycystic Liver Disease: A Study of Cyst Fluid Constituents

1982 • 52 citations

A microdissection study of cystic disease of the kidneys in adults

1966 • 51 citations

Cyst-derived cells do not exhibit accelerated growth or features of transformed cells in vitro

1989 • 50 citations

Altered basement membrane protein biosynthesis by primary cultures of cpk/cpk mouse kidney

1990 • 49 citations

Fertility and pregnancy complications in women with autosomal dominant polycystic kidney disease.

1983 • 49 citations

pH-Dependent Accumulation of Clindamycin in a Polycystic Kidney

1983 • 49 citations

The Importance of Selective Renal Angiography in the Diagnosis of Polycystic Disease

1969 • 48 citations

Trimethoprim-sulfamethoxazole in cyst fluid from autosomal dominant polycystic kidneys

1987 • 47 citations

Nephrogenous Polycythaemia

1958 • 47 citations

High-density renal cysts in autosomal dominant polycystic kidney disease demonstrated by CT.

1985 • 46 citations

Cranial computed tomography and magnetic resonance imaging in autosomal dominant polycystic kidney disease.

1990 • 45 citations

Autosomal Dominant Polycystic Kidney Disease: Early Diagnosis and Consideration of Pathogenesis

1980 • 43 citations

Aberrant Epithelial Cell Growth in Autosomal Dominant Polycystic Kidney Disease

1991 • 43 citations

Autosomal Dominant Polycystic Kidney Disease With Liver and Pancreatic Involvement in Early Childhood

1989 • 42 citations

Inherited polycystic kidney disease in children.

1991 • 40 citations

Renal Cysts in Pediatric Autopsy Material

1983 • 40 citations

Sequential tubular cell and basement membrane changes in polycystic kidney disease.

1992 • 38 citations

Erythropoietin and anemia in chronic renal failure.

1987 • 38 citations

Understanding human cystic disease through experimental models.

1991 • 38 citations

Intracranial Aneurysms and Polycystic Kidneys

1960 • 36 citations

Extrarenal manifestations of autosomal dominant polycystic kidney disease.

1991 • 35 citations

Renal cyst formation and multifocal neoplasia in transgenic mice carrying the simian virus 40 early region.

1991 • 33 citations

Simple Serous Cysts of the Kidney in Children

1979 • 30 citations

Renal manifestations: complication management and long-term outcome of autosomal dominant polycystic kidney disease.

1991 • 29 citations

The congenital aneurysm of the basal arteries and cystic kidneys.

1949 • 28 citations

Uric acid handling in autosomal dominant polycystic kidney disease with normal filtration rates

1990 • 28 citations

In vitro modulation of tubular cyst regression in murine polycystic kidney disease

1989 • 27 citations

Simple Renal Cysts in Children

1982 • 25 citations

Fluid transport in a cultured cell model of kidney epithelial cyst enlargement.

1992 • 25 citations

Angiography in Polycystic Disease of the Kidneys

1970 • 23 citations

Gene Testing in Autosomal Dominant Polycystic Kidney Disease: Results of National Kidney Foundation Workshop

1989 • 22 citations

Basement membrane alterations during development and regression of tubular cysts

1990 • 22 citations

Gentamicin concentrations in blood, urine, and renal tissue of patients with end-stage renal disease.

1977 • 21 citations

Mechanisms affecting the development of renal cystic disease induced by diphenylthiazole

1988 • 19 citations

The genetics of cystic diseases of the kidney.

1991 • 19 citations

Intra- and extracellular proteins in human normal and polycystic kidney epithelial cells

1990 • 19 citations

Incidence of Renal Lesions in Polycythaemia

1963 • 19 citations

Efficacy of Chloramphenicol in Refractory Cyst Infections in Autosomal Dominant Polycystic Kidney Disease

1985 • 19 citations

A membranous nephropathy associated with adult polycystic kidney disease.

1991 • 18 citations

Renal pain in polycystic kidney disease: when the hurt won't stop.

1992 • 18 citations

SIMPLE RENAL CYSTS IN CHILDHOOD

2008 • 18 citations

Hypertension in polycystic kidney disease without renal failure

1977 • 17 citations

Presymptomatic testing for adult onset polycystic kidney disease in at‐risk kidney transplant donors

1991 • 17 citations

Nephrotic Syndrome and Rapid Renal Failure in Autosomal Dominant Polycystic Kidney Disease

1990 • 16 citations

Autosomal Dominant Polycystic Kidney Disease Complicated by Glomerulonephritis

1992 • 11 citations

Renal pain in polycystic kidney disease

1992 • 11 citations

Prediction of Likelihood of Polycystic Kidney Disease in the Fetus When a Parent has Autosomal Dominant Polycystic Kidney Disease

1991 • 9 citations

Management of Cystic Kidney Disease

1990 • 9 citations

Urinary tract infections in patients with severe renal disease. Treatment with ampicillin and trimethoprim-sulfamethoxazole

1976 • 7 citations

Health insurance and life insurance in patients with autosomal dominant polycystic kidney disease

1992 • 4 citations

Polycystic kidney disease, polycythemia, and azotemia

1969 • 3 citations

Adult polycystic kidney disease in Ethiopians.

1983 • 3 citations