Mechanisms of ring chromosome formation in 11 cases of human ring chromosome 21.

A simple technique for demonstrating centromeric heterochromatin

1972 • 4,206 citations

Visualization of nucleolar organizer regions in mammalian chromosomes using silver staining

1975 • 1,131 citations

Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome.

1989 • 261 citations

Does ?ring syndrome? exist? An analysis of 207 case reports on patients with a ring autosome

1987 • 252 citations

Molecular definition of a region of chromosome 21 that causes features of the Down syndrome phenotype.

1990 • 241 citations

Molecular genetic approach to the characterization of the ?Down syndrome region? of chromosome 21

1989 • 195 citations

Mutation rates of structural chromosome rearrangements in man.

1981 • 137 citations

A map of the distal region of the long arm of human chromosome 21 constructed by radiation hybrid mapping and pulsed-field gel electrophoresis

1991 • 124 citations

Use of short sequence repeat DNA polymorphisms after PCR amplification to detect the parental origin of the additional chromosome 21 in Down syndrome.

1991 • 87 citations

Clinical diagnosis of Down's syndrome

1976 • 86 citations

A genetic linkage map of 27 markers on human chromosome 21

1991 • 79 citations

Cloning and expression of the human S100 beta gene.

1990 • 76 citations

Linkage analysis of the human HMG14 gene on chromosome 21 using a GT dinucleotide repeat as polymorphic marker

1990 • 60 citations

Molecular mechanism in the formation of a human ring chromosome 21.

1989 • 51 citations

[On the duplication of circular structures].

1968 • 38 citations

A case of partial monosomy 21q22.2 associated with Rieger's syndrome.

1984 • 34 citations

Linkage mapping of the highly informative DNA marker D21S156 to human chromosome 21 using a polymorphic GT dinucleotide repeat

1990 • 29 citations

Prenatal detection of an unstable ring 21 chromosome

1984 • 23 citations

Dinucleotide repeat polymorphism located at D21S120

1990 • 23 citations

A case of r(21) with stigmata of atypical Down syndrome

1980 • 19 citations

Familial transmission of a ring chromosome 21

1987 • 16 citations

Evidence for involvement of a Robertsonian translocation 13 chromosome in formation of a ring chromosome 13.

1990 • 15 citations