In vitro culture of common acute lymphoblastic leukemia blasts: effects of interleukin-3, interleukin-7, and accessory cells

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

Immunologic classification of leukemia and lymphoma.

1986 • 773 citations

Long-term culture of B lymphocytes and their precursors from murine bone marrow.

1982 • 612 citations

Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.

1981 • 576 citations

KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections.

1989 • 485 citations

B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors.

1988 • 379 citations

Molecular and cellular origins of B lymphocyte diversity

1991 • 346 citations

Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.

1991 • 335 citations

B cell ontogeny in murine embryo studied by a culture system with the monolayer of a stromal cell clone, ST2: B cell progenitor develops first in the embryonal body rather than in the yolk sac.

1988 • 292 citations

Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.

1989 • 288 citations

Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule

1987 • 254 citations

A Model of Human Acute Lymphoblastic Leukemia in Immune-Deficient SCID Mice

1989 • 250 citations

Interleukin 7 production and function in stromal cell-dependent B cell development.

1989 • 221 citations

Lymphoid Blast Crises of Chronic Myelogenous Leukemia Represent Stages in the Development of B-Cell Precursors

1983 • 215 citations

A single bone marrow-derived stromal cell type supports the in vitro growth of early lymphoid and myeloid cells

1987 • 207 citations

Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia

1990 • 158 citations

Mac 387 antibody and detection of formalin resistant myelomonocytic L1 antigen.

1988 • 121 citations

T cell receptor-CD3 complex during early T cell differentiation. Analysis of immature T cell acute lymphoblastic leukemias (T-ALL) at DNA, RNA, and cell membrane level.

1987 • 118 citations

Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin.

1991 • 92 citations

Leukemic B-cell precursors express functional receptors for human interleukin-3

1989 • 82 citations

In vitro effects of recombinant interleukin 7 on growth and differentiation of bone marrow pro-B- and pro-T-lymphocyte clones and fetal thymocyte clones.

1989 • 80 citations

One synchronous wave of B cell development in mouse fetal liver changes at day 16 of gestation from dependence to independence of a stromal cell environment.

1989 • 75 citations

Pre-B cell generation potentiated by soluble factors from a bone marrow stromal cell line.

1988 • 74 citations

Proliferative effect of interleukin-3 on normal and leukemic human B cell precursors.

1989 • 72 citations

Acute undifferentiated leukemia: implications for cellular origin and clonality suggested by analysis of surface markers and immunoglobulin gene rearrangement

1986 • 70 citations

Effects of recombinant human IL-7 on blast cell proliferation in acute lymphoblastic leukemia.

1990 • 49 citations

Bone marrow stromal cell regulation of B lymphopoiesis: interleukin-1 (IL-1) and IL-4 regulate stromal cell support of pre-B cell production in vitro

1990 • 43 citations

Long-term proliferation of human leukemia cells induced by mouse stroma.

1989 • 42 citations

Recombinant hematopoietic growth factors fail to induce a proliferative response in precursor B acute lymphoblastic leukemia.

1989 • 41 citations

Transformation-associated alterations in interactions between pre-B cells and fibronectin

1990 • 37 citations

IL-3 and stromal cell-derived factor synergistically stimulate the growth of pre-B cell lines cloned from long-term lymphoid bone marrow cultures.

1989 • 33 citations

Post-irradiation regeneration of early B-lymphocyte precursor cells in mouse bone marrow.

1989 • 30 citations

Growth requirements for human acute lymphoblastic leukemia cells: refinement of a clonogenic assay.

1988 • 29 citations

Early B-lymphocyte precursor cells in mouse bone marrow: subosteal localization of B220+ cells during postirradiation regeneration.

1990 • 29 citations

Regulation of B-lymphocyte production in the bone marrow: Role of macrophages and the spleen in mediating responses to exogenous agents

1985 • 23 citations

The Lymphopoietic Microenvironment in Bone Marrow

1990 • 23 citations

Effects of low molecular weight B-cell growth factor on proliferation of leukemic cells from children with B-cell precursor-acute lymphoblastic leukemia

1990 • 21 citations

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