Regional gastrointestinal absorption of the beta-blocker pafenolol in the rat and intestinal transit rate determined by movement of 14C-polyethylene glycol (PEG) 4000.

Transit of pharmaceutical dosage forms through the small intestine.

1986 • 849 citations

Observations on the flora of the alimentary tract of animals and factors affecting its composition

1965 • 458 citations

The influence of variable gastric emptying and intestinal transit rates on the plasma level curve of cimetidine; an explanation for the double peak phenomenon

1987 • 207 citations

Different fibers have different regional effects on luminal contents of rat colon

1991 • 144 citations

PC-SIZE: A Program for Sample-Size Determinations

1986 • 144 citations

Pharmacokinetic interpretation of the enterohepatic recirculation and first-pass elimination of morphine in the rat

1978 • 98 citations

A double-peak phenomenon in the pharmacokinetics of veralipride after oral administration: A double-site model for drug absorption

1987 • 93 citations

Use of Radioyttrium to Study Food Movement in the Small Intestine of the Rat

1962 • 88 citations

The influence of levodopa on gastric emptying in man.

1990 • 71 citations

Penicillamine kinetics in normal subjects

1981 • 70 citations

Estimation of drug absorption rates using a deconvolution method with nonequal sampling times

1986 • 56 citations

NONLIN84/PCNONLIN: software for the statistical analysis of nonlinear models.

1986 • 53 citations

Interaction between intestinal absorption and secretion of monoquaternary ammonium compounds in guinea pigs--a concept for the absorption kinetics of organic cations.

1980 • 52 citations

Intestinal absorption of a .BETA.-adrenergic blocking agent nadolol. II Mechanism of the inhibitory effect on the intestinal absorption of nadolol by sodium cholate in rats.

1986 • 45 citations

Dose-dependent intestinal absorption and significant intestinal excretion (exsorption) of the beta-blocker pafenolol in the rat.

1993 • 41 citations

Intestinal absorption of a .BETA.-adrenergic blocking agent nadolol. I Comparison of absorption behavior of nadolol with those of other .BETA.-blocking agents in rats.

1986 • 36 citations

Pharmacokinetics of a single intravenous and oral dose of pafenolol--a beta 1-adrenoceptor antagonist with atypical absorption and disposition properties--in man.

1990 • 16 citations

Pharmacokinetics of pafenolol after IV and oral administration of three separate doses of different strength to man

1990 • 14 citations

A comparison of small intestinal transit time between the rat and the guinea-pig.

1976 • 14 citations

Pharmacokinetics of pafenolol in the rat: A suitable model for studying absorption mechanisms of a drug exhibiting unusual absorption properties in man

1990 • 11 citations

Relationship between the first-order intestinal absorption rate constant in vivo and the membrane permeability clearance in a perfusion system: An intragastric administration method in vivo.

1989 • 8 citations

Small bowel propulsive motility in the rat. Studies with open and closed pylorus.

1972 • 2 citations