STEPS IN PROCESSING OF mRNA: IMPLICATIONS FOR GENE REGULATION

Genetic regulatory mechanisms in the synthesis of proteins

1961 • 6,378 citations

Spliced segments at the 5′ terminus of adenovirus 2 late mRNA

1977 • 1,301 citations

Capping of eucaryotic mRNAs

1976 • 1,141 citations

An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA

1977 • 1,138 citations

Termination Factor for RNA Synthesis

1969 • 801 citations

Control of Transcription Termination

1978 • 618 citations

Eukaryotic Nuclear RNA Polymerases

1975 • 491 citations

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

1978 • 478 citations

Biogenesis of mRNA: Genetic Regulation in Mammalian Cells

1973 • 398 citations

Coincidence of the promoter and capped 5′ terminus of RNA from the adenovirus 2 major late transcription unit

1978 • 390 citations

Ribonucleic acids from animal cells

1968 • 379 citations

Transcription and processing of intervening sequences in yeast tRNA genes

1978 • 332 citations

A map of cytoplasmic RNA transcripts from lytic adenovirus type 2, determined by electron microscopy of RNA:DNA hybrids

1977 • 303 citations

Two adenovirus mRNAs have a common 5′ terminal leader sequence encoded at least 10 kb upstream from their main coding regions

1977 • 283 citations

Complexity and characterization of polyadenylated RNA in the mouse brain

1976 • 250 citations

New Features of the Regulation of the Tryptophan Operon

1975 • 245 citations

THE TURNOVER OF NUCLEAR DNA-LIKE RNA IN HELA CELLS

1968 • 219 citations

Units of transcription and translation: the relationship between heterogeneous nuclear RNA and messenger RNA

1975 • 219 citations

On the structural organization of operon and the regulation of RNA synthesis in animal cells

1969 • 216 citations

The initiation sites for RNA transcription in Ad2 DNA

1977 • 208 citations

Mapping the spliced and unspliced late lytic SV40 RNAs

1978 • 193 citations

The methylation of adenovirus-specific nuclear and cytoplasmic RNA

1976 • 186 citations

Transcription Units for mRNA Production in Eukaryotic Cells and Their DNA Viruses

1979 • 173 citations

Biosynthesis and stability of globin mRNA in cultured erythroleukemic friend cells

1976 • 163 citations

Nucleotide sequence of the leader region of the phenylalanine operon of Escherichia coli

1978 • 156 citations

Messenger RNA in avian erythroblasts at the transcriptional and translational levels and the problem of regulation in animal cells

1968 • 155 citations

Sequence complexity of nuclear RNAs in adult rat tissues

1978 • 146 citations

The topography and transcription of the adenovirus genome

1977 • 138 citations

Groups of adenovirus type 2 mRNA's derived from a large primary transcript: probable nuclear origin and possible common 3' ends

1978 • 132 citations

In Vitro Transcription

1972 • 125 citations

The definition of a large viral transcription unit late in Ad2 infection of HeLa cells: Mapping by effects of ultraviolet irradiation

1977 • 121 citations

Ultraviolet mapping of the adenovirus 2 early promoters

1977 • 100 citations

Adenovirus-2 mRNA is transcribed as part of a high-molecular-weight precursor RNA.

1975 • 100 citations

Localization of the HU Protein on the Escherichia coli Nucleoid

1978 • 99 citations

hnRNA size and processing as related to different DNA content in two dipterans: Drosophila and aedes

1975 • 94 citations

Electron Microscopic Visualization of Transcription

1970 • 82 citations

An analysis of “revertants” of a deletion mutant in the C gene of the l-arabinose gene complex in Escherichia coli B/r: Isolation of initiator constitutive mutants (Ic)

1969 • 80 citations

In vitro RNA-RNA splicing in adenovirus 2 mRNA formation.

1978 • 79 citations

Adenovirus type 2 late mRNA's: structural evidence for 3'-coterminal species

1978 • 72 citations

hnRNA in HeLa cells: Distribution of transcript sizes estimated from nascent molecule profile

1976 • 67 citations

RNA structures near poly(A) of adenovirus-2 late messenger RNAs

1978 • 66 citations

Two regions of the adenovirus 2 genome specify families of late polysomal RNAs containing common sequences.

1978 • 60 citations

Definition of subclasses of nucleoplasmic RNA

1977 • 56 citations

Essential factors in the kinetic analysis of RNA synthesis in HeLa cells

1977 • 56 citations

Localization of the 5′ terminus of late SV40 mRNA

1978 • 47 citations

A characterization of globin mRNA sequences in the nucleus of duck immature red blood cells

1977 • 41 citations

Evidence from UV transcription mapping that late adenovirus type 2 mRNA is derived from a large precursor molecule

1978 • 38 citations

Coupling of lac mRNA transcription to translation in Escherichia coli cell extracts

1978 • 12 citations