A complex of N5,N10-methylenetetrahydrofolate dehydrogenase and N5,N10-methenyltetrahydrofolate cyclohydrolase in Escherichia coli. Purification, subunit structure, and allosteric inhibition by N10-formyltetrahydrofolate.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*

1964 • 18,916 citations

Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane

1971 • 8,619 citations

DISC ELECTROPHORESIS‐I BACKGROUND AND THEORY*

1964 • 4,551 citations

Statistical estimations in enzyme kinetics

1961 • 3,586 citations

The gel-filtration behaviour of proteins related to their molecular weights over a wide range

1965 • 3,062 citations

Allosteric proteins and cellular control systems

1963 • 2,187 citations

Molecular Weight Determination of Protein-Dodecyl Sulfate Complexes by Gel Electrophoresis in a Discontinuous Buffer System

1971 • 2,019 citations

A procedure for rapid and sensitive staining of protein fractionated by polyacrylamide gel electrophoresis

1967 • 1,142 citations

The Biochemistry of Folic Acid and Related Pteridines.

1970 • 1,033 citations

Some comments on the Benesi‐Hildebrand equation

1956 • 505 citations

Kinetics of Regulatory Enzymes

1965 • 390 citations

The Effect of Carbon and Nitrogen Sources on the Level of Metabolic Intermediates in Escherichia coli

1971 • 350 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1969 • 272 citations

Formyl-methyl-methylenetetrahydrofolate synthetase-(combined). An ovine protein with multiple catalytic activities.

1976 • 122 citations

[84] Methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase: A multifunctional protein from porcine liver

1980 • 118 citations

The Structure of “Active Formaldehyde” (N⁵, N¹⁰ -Methylene Tetrahydrofolic Acid)¹

1960 • 118 citations

On the occurrence of N10-formyltetrahydrofolic acid by enzymic formylation of tetrahydrofolic acid and on the mechanism of this reaction

1955 • 106 citations

Use of Brij lysis as a general method to prepare polyribosomes from Escherichia coli

1967 • 103 citations

Methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase. A multifunctional protein from porcine liver.

1977 • 100 citations

The Control of Ribonucleic Acid Synthesis in Escherichia coli

1969 • 99 citations

Purification and Characterization of Thermostable 5,10-Methylenetetrahydrofolate Dehydrogenase from Clostridium thermoaceticum

1973 • 78 citations

Growth and Initiation of Protein Synthesis inEscherichia coliin the Presence of Trimethoprim

1973 • 76 citations

Enzymes of Clostridial Purine Fermentation

1967 • 72 citations

Occurrence of N10-formyltetrahydrofolic acid and its general involvement in transformylation

1955 • 69 citations

The Effects of Bases and Nucleosides on the Intracellular Contents of Nucleotides and 5‐Phosphoribosyl 1‐pyrophosphate in Escherichia coli

1974 • 63 citations

Genetic Blocks and Unique Features in the Biosynthesis of 5′-Phosphoribosyl-N-formylglycinamide in Salmonella typhimurium

1969 • 45 citations

Control of one-carbon metabolism in a methionine-B12 auxotroph of Escherichia coli

1966 • 41 citations

N10-Formyltetrahydrofolate is the formyl donor for glycinamide ribotide transformylase in Escherichia coli.

1978 • 35 citations

Relationship between the concentration of nucleoside triphosphates and the rate of synthesis of RNA

1973 • 34 citations

[9] The enzymes of purine nucleotide synthesis de novo

1963 • 33 citations

Mammalian folate metabolism. Regulation of folate interconversion enzymes

1973 • 28 citations

Biosynthesis of single-carbon units in Escherichia coli K12

1974 • 27 citations

Regulation in the foláte pathway of Escherichia coli

1975 • 26 citations

[96] Intermediates in purine nucleotide synthesis

1963 • 22 citations

Purification of 5,10-Methylenetetrahydrofolate Dehydrogenase from Salmonella typhimurium and Its Inhibition by Purine Nucleotides

1967 • 21 citations

Enzymatic preparation of the (+),L-diastereoisomer of [methenyl-14C]-N5,N-10-methenyltetrahydrofolic acid

1967 • 19 citations

[51] Formyltetrahydrofolate synthetase

1963 • 19 citations

Purification and Properties of 5,10-Methylenetetrahydrofolate Dehydrogenase from Escherichia coli

1965 • 15 citations