Improved Synthesis of 6-[p-(Bromoacetamido)benzyl]- 1,4,8,11-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic Acid and Development of a Thin-Layer Assay for Thiol-Reactive Bifunctional Chelating Agents

Tissue sulfhydryl groups

1959 • 25,130 citations

Addition of sulfhydryl groups of Escherichia coli ribosomes by protein modification with 2-iminothiolane (methyl 4-mercaptobutyrimidate)

1978 • 201 citations

Copper chelates as probes of biological systems: Stable copper complexes with a macrocyclic bifunctional chelating agent

1985 • 195 citations

Metal chelates as probes of biological systems

1984 • 184 citations

Convenient synthesis of bifunctional tetraaza macrocycles

1992 • 114 citations

Copper-67-labeled monoclonal antibody Lym-1, a potential radiopharmaceutical for cancer therapy: labeling and biodistribution in RAJI tumored mice.

1988 • 100 citations

Simplified method for conjugating macrocyclic bifunctional chelating agents to antibodies via 2-iminothiolane

1990 • 98 citations

Chelating agents for the binding of metal ions to macromolecules

1974 • 88 citations

Pharmacokinetics of pretargeted monoclonal antibody 2D12.5 and 88Y-Janus-2-(p-nitrobenzyl)-1,4,7,10-tetraazacyclododecanetetraacetic acid (DOTA) in BALB/c mice with KHJJ mouse adenocarcinoma: a model for 90Y radioimmunotherapy.

1994 • 83 citations

A comparative study of copper-67 radiolabeling and kinetic stabilities of antibody-macrocycle chelate conjugates

1994 • 62 citations

Antibody labelling with functionalised cyclam macrocycles

1988 • 48 citations

In vivo comparison of copper blood-pool agents: potential radiopharmaceuticals for use with copper-62.

1991 • 47 citations

Pretargeted immunoscintigraphy: effect of hapten valency on murine tumor uptake.

1992 • 46 citations

Synthesis and evaluation of two new bifunctional carboxymethylated tetraazamacrocyclic chelating agents for protein labeling with indium-111

1990 • 42 citations

Towards tumour targeting with copper-radiolabelled macrocycle–antibody conjugates

1989 • 27 citations

Antibody-mediated radiotherapy

1985 • 25 citations