Molecular cloning of the human CTP synthetase gene by functional complementation with purified human metaphase chromosomes.

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

The molecular basis of mutations induced by deoxyribonucleoside triphosphate pool imbalances in mammalian cells

1989 • 222 citations

Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme.

1989 • 183 citations

Spontaneous deletion formation at the aprt locus of hamster cells: the presence of short sequence homologies and dyad symmetries at deletion termini.

1986 • 158 citations

Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase.

1986 • 149 citations

Nucleotide sequence of a functional cDNA for human thymidylate synthase

1985 • 141 citations

Parameters governing the transfer of the genes for thymidine kinase and dihydrofolate reductase into mouse cells using metaphase chromosomes or DNA

1980 • 139 citations

Characterization of a mutator gene in Chinese hamster ovary cells.

1979 • 129 citations

Nucleotide sequence of Escherichia coli pyrG encoding CTP synthetase.

1986 • 118 citations

Cloned mouse ribonucleotide reductase subunit M1 cDNA reveals amino acid sequence homology with Escherichia coli and herpesvirus ribonucleotide reductases.

1985 • 85 citations

Role of deoxynucleoside triphosphate pools in the cytotoxic and mutagenic effects of DNA alkylating agents

1981 • 84 citations

Co-transfer of human X-linked markers into murine somatic cells via isolated metaphase chromosomes

1978 • 82 citations

Molecular and physical arrangements of human DNA in HRAS1-selected, chromosome-mediated transfectants.

1986 • 43 citations

Biochemical phenotype of 5-fluorouracil-resistant murine T-lymphoblasts with genetically altered CTP synthetase activity.

1984 • 42 citations

Isolation and Characterization of Expressible cDNA Clones Encoding the M1 and M2 Subunits of Mouse Ribonucleotide Reductase

1986 • 40 citations

Cooperative effects of CTP on calf liver CTP synthetase.

1979 • 33 citations

Investigation of chromosome-mediated gene transfer using the HPRT region of the human X chromosome as a model.

1987 • 29 citations

Purification of cytidine-triphosphate synthetase from rat liver, and demonstration of monomer, dimer and tetramer

1988 • 27 citations

Altered CTP synthetase activity confers resistance to 5-bromodeoxyuridine toxicity and mutagenesis

1986 • 26 citations

A selection system specific for the thy mutator phenotype

1982 • 26 citations

Pleiotropic mutants of Chinese hamster cells with altered cytidine 5?-triphosphate synthetase

1984 • 24 citations

Molecular and Physical Arrangements of Human DNA in HRAS1-Selected, Chromosome-Mediated Transfectants

1986 • 14 citations

Direct selection of chinese hamster ovary strains deficient in CTP synthetase activity

1988 • 14 citations

CTP synthetase from Ehrlich ascites tumor cells. Subunit stoichiometry and regulation of activity

1985 • 12 citations

Two types of mouse FM3A cell mutants deficient in 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and their transformants isolated by human chromosome-mediated gene transfer

1989 • 6 citations

The Genetic Consequences of the Thy- Mutation to CHO Cells

1985 • 2 citations