Inhibition of T and B lymphocyte proliferation by rapamycin.

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1989 • 1,414 citations

A receptor for the immuno-suppressant FK506 is a cis–trans peptidyl-prolyl isomerase

1989 • 1,376 citations

FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro.

1987 • 1,209 citations

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

1989 • 1,087 citations

FK 506 FOR LIVER, KIDNEY, AND PANCREAS TRANSPLANTATION

1989 • 1,043 citations

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

1989 • 1,010 citations

Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization.

1975 • 908 citations

Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin.

1990 • 613 citations

Inhibition of the immune response by rapamycin, a new antifungal antibiotic

1977 • 444 citations

Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation.

1987 • 416 citations

The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells.

1990 • 360 citations

CYCLOSPORINE, FK506, AND RAPAMYCIN

1990 • 97 citations

Inhibition of T-lymphocyte activation by the immunosuppressive drug FK-506.

1989 • 69 citations

A study of the contrasting effects of cyclosporine, FK 506, and rapamycin on the suppression of allograft rejection.

1990 • 52 citations

The mechanism of action of the immunosuppressive drug FK-506

1989 • 37 citations

Inhibition of murine B-lymphocyte proliferation by the novel immunosuppressive drug FK-506.

1989 • 33 citations

Inhibition of proliferation of a murine myeloma cell line and mitogen-stimulated B lymphocytes by the antibiotic amphotericin B (Fungizone).

1982 • 31 citations

Effects of cyclosporin A on the metabolism of unstimulated and mitogen-activated lymphocytes.

1983 • 29 citations

The mechanism of action of FK 506.

1990 • 25 citations

T lymphocyte activation through the C28 pathway is insensitive to inhibition by the immunosuppressive drug FK-506

1989 • 18 citations

Cyclosporin as a probe for different modes of lymphocyte activation

1987 • 11 citations