Evaluation for Immunosuppressive and Antiallergic Activity

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs.

1968 • 1,363 citations

Development of Arthritis, Periarthritis and Periostitis in Rats Given Adjuvants.

1956 • 847 citations

Cytotoxic Effects of Lymphoid Cells in Vitro

1969 • 643 citations

A METHOD OF STUDYING LEUKOCYTIC FUNCTIONS IN VIVO

1955 • 619 citations

CHEMOTHERAPY OF ARTHRITIS INDUCED IN RATS BY MYCOBACTERIAL ADJUVANT

1963 • 523 citations

Disodium Cromoglycate (FPL 670) (‘Intal’*): a Specific Inhibitor of Reaginic Antibody–Antigen Mechanisms

1967 • 440 citations

MECHANISMS OF LYSOSOMAL ENZYME RELEASE FROM LEUKOCYTES EXPOSED TO IMMUNE COMPLEXES AND OTHER PARTICLES

1971 • 439 citations

Immediate Reactions in the Skin of Experimental Animals Provoked by Antibody-Antigen Interaction

1958 • 422 citations

Specific inhibition of antibody production. II. Paralysis induced in adult mice by small quantities of protein antigen.

1962 • 386 citations

Immunological Methods

1963 • 354 citations

Micromethods for the Study of Proteins and Antibodies

1954 • 352 citations

IMMUNOLOGICAL RELEASE OF HISTAMINE AND SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS FROM HUMAN LUNG

1971 • 338 citations

Studies of arthritis and other lesions induced in rats by injection of mycobacterial adjuvant. II. Evidence that the disease is a disseminated immunologic response to exogenous antigen.

1960 • 336 citations

Determination of Cell Viability

1958 • 327 citations

METHOTREXATE REGIMENS FOR CONTROL OF GRAFT-VERSUS-HOST DISEASE IN DOGS WITH ALLOGENEIC MARROW GRAFTS

1970 • 320 citations

STUDIES ON THE GENERALIZED SHWARTZMAN REACTION

1952 • 300 citations

Experimental Allergic Encephalomyelitis and Autoimmune Disease

1966 • 282 citations

Effect of Prostaglandin E1 on Adjuvant Arthritis

1971 • 264 citations

A Familial Deficiency of the Phagocytosis-Enhancing Activity of Serum Related to a Dysfunction of the Fifth Component of Complement (C5)

1970 • 259 citations

In Vitro Approaches to the Mechanism of Cell-Mediated Immune Reactions

1971 • 258 citations

INTERACTIONS BETWEEN RABBIT POLYMORPHONUCLEAR LEUCOCYTES AND STAPHYLOCOCCI

1959 • 257 citations

THE USE OF SPECIFIC "LYMPHOCYTE" ANTISERA TO INHIBIT HYPERSENSITIVE REACTIONS OF THE "DELAYED" TYPE

1961 • 256 citations

Immunosuppressive Therapy

1967 • 247 citations

THE CHEMOSUPPRESSION OF CHEMOTAXIS

1966 • 240 citations

Chemical Suppression of Adaptive Immunity

1967 • 238 citations

BOUND COMPLEMENT AND IMMUNOLOGIC INJURY OF BLOOD VESSELS

1965 • 238 citations

DEPOT-METHYLPREDNISOLONE FOR SUBCONJUNCTIVAL AND RETROBULBAR INJECTIONS

1961 • 230 citations

A STUDY OF THE EFFECTS OF DRUGS IN PROLONGING SURVIVAL OF HOMOLOGOUS RENAL TRANSPLANTS IN DOGS*

1962 • 229 citations

A Localized Haemolysis in Gel Method for the Detection of Cells Producing 7S Antibody: Detection of Cells producing 7S Antibodies by the Plaque Technique

1965 • 223 citations

Studies of arthritis and other lesions induced in rats by the injection of mycobacterial adjuvant. VII. Pathologic details of the arthritis and spondylitis.

1963 • 210 citations

CHEMOTAXIS OF MONONUCLEAR CELLS

1968 • 209 citations

STUDIES OF ARTHRITIS AND OTHER LESIONS INDUCED IN RATS BY INJECTION OF MYCOBACTERIAL ADJUVANT

1961 • 202 citations

The Natural History of Autoimmune Disease in NZB Mice

1963 • 200 citations

Transformation of Human Lymphocytes: Inhibition by Homologous Alpha Globulin

1968 • 199 citations

Cellular Immunology and the Pathogenesis of Graft Versus Host Reactions1

2015 • 198 citations

Biochemistry of the acute allergic reactions

1969 • 190 citations

Studies of Arthritis and Other Lesions Induced in Rats by Injection of Mycobacterial Adjuvant

1960 • 188 citations

Inhibition of the anaphylactic reaction

1957 • 183 citations

T and B Lymphocytes and Immune Responses

1973 • 183 citations

Inhibition of human leukocyte mitosis by prednisolone in vitro.

1961 • 181 citations

Chemical Suppression of the Immune Response

1962 • 177 citations

THE EFFECT OF 6-MERCAPTOPURINE ON PRIMARY AND SECONDARY IMMUNE RESPONSES *

1959 • 176 citations

APPLICATION OF A LOCALIZED HEMOLYSIN REACTION FOR SPECIFIC DETECTION OF INDIVIDUAL ANTIBODY-FORMING CELLS

1964 • 162 citations

Spontaneous Auto‐Immune Disease in NZB/BL Mice

1963 • 159 citations

STUDIES ON THE MECHANISM OF THE SHWARTZMAN PHENOMENON

1951 • 144 citations

Colchicine inhibition of chemotaxis

1965 • 144 citations

Immunologic and viral factors in the pathogenesis of systemic lupus erythematosus

1970 • 143 citations

Diagnosis of drug allergy in vitro with the lymphocyte transformation test

1967 • 143 citations

Cellular and Humoral Mechanisms in Anaphylaxis and Allergy.

1970 • 143 citations

Colchicine: a common mechanism for its anti‐inflammatory and anti‐mitotic effects

1968 • 140 citations

Inflammation, Immunity, and Hypersensitivity

1971 • 140 citations

A histologic study of the early lesion in experimental allergic encephalomyelitis in the guinea pig and rabbit.

1962 • 139 citations

The Immediate Allergic Response: in Vitro Action of Cyclic Amp-Active and Other Drugs on the Two Stages of Histamine Release

1971 • 138 citations

Prolongation of Homograft Survival in Mice with Single Doses of Cyclophosphamide

1963 • 136 citations

Experimental Studies on the Pathogenesis of Contact Eczema in the Guinea-Pig

1957 • 136 citations

Immunological Tolerance of Nonliving Antigens

1961 • 136 citations

Suppression of in Vitro Lymphocyte Responses by Chloroquine

1965 • 135 citations

Adjuvant-induced arthritis in rats. II. Drug effects on physiologic, biochemical and immunologic parameters.

1971 • 134 citations

Enhancement of Dinitrochlorobenzene (DNCB) Contact Sensitization by Cyclophosphamide in the Guinea Pig**From the Department of Dermatology, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104.

1967 • 133 citations

The Role of Cyclic AMP in the Cytolytic Activity of Lymphocytes

1971 • 130 citations

Passive cutaneous anaphylaxis in the rat, induced with two homologous reagin-like antibodies and its specific inhibition with disodium cromoglycate.

1969 • 127 citations

Tolerance to a Protein Antigen in Adult Mice and the Effect of Nonspecific Factors

1963 • 126 citations

In vitro methods in cell-mediated immunity

1970 • 125 citations

AUTO-IMMUNIZATION AND THE LESIONS OF AUTO-IMMUNITY

1962 • 121 citations

AN IMPROVED FLUOROGHROMATIC CYTOTOXIC TEST

1971 • 121 citations

Treatment of adjuvant arthritis in rats with anti‐inflammatory drugs

1966 • 119 citations

Studies of allograft immunity in mice. II. Mechanism of target cell inactivation in vitro by sensitized lymphocytes.

1970 • 118 citations

Immunopathology of Inflammation

1972 • 117 citations

Possible Role of Leucocyte Granules in the Shwartzman and Arthus Reactions.

1964 • 116 citations

Antigen Induced Release of Histamine and SRS-A from Human Lung passively sensitized with Reaginic Serum

1967 • 116 citations

A HYPERACUTE FORM OF ALLERGIC ENCEPHALOMYELITIS.

1965 • 116 citations

CYCLOPHOSPHAMIDE TREATMENT OF RENAL DISEASE IN (NZB &times; NZW) F1 HYBRID MICE

1968 • 115 citations

The Anaphylactic Antibodies of Mammals Including Man*

2015 • 114 citations

CENTRAL AND PERIPHERAL EFFECTS OF ANTI-LYMPHOCYTE SERA

1967 • 113 citations

Inhibition of Allergic Reactions in Man and Other Species by Cromoglycate

1970 • 113 citations

DOSE-RESPONSE RELATIONSHIPS FOR AGENTS INHIBITING THE IMMUNE RESPONSE.

1964 • 111 citations

HUMORAL FACTORS AFFECTING PULMONARY INFLATION DURING ACUTE ANAPHYLAXIS IN THE GUINEA‐PIG IN VIVO

1967 • 110 citations

SUPPRESSION OF DELAYED HYPERSENSITIVITY IN VITRO BY INHIBITION OF PROTEIN SYNTHESIS

1965 • 110 citations

SUPPRESSION OF ADJUVANT DISEASE IN THE RAT BY HETEROLOGOUS ANTILYMPHOCYTE GLOBULIN

1968 • 109 citations

The Experimental Production of Arthritis: A Review

1960 • 107 citations

IMPAIRED LEUCOTACTIC RESPONSIVENESS IN A CHILD WITH RECURRENT INFECTIONS

1969 • 106 citations

ANTIBODY FORMATION IN VOLUNTEERS FOLLOWING INJECTION OF PNEUMOCOCCI OR THEIR TYPE-SPECIFIC POLYSACCHARIDES

1946 • 105 citations

Immunological diseases

1966 • 103 citations

Inhibition of the Local Inflammatory Response in Man by Antimetabolites

1966 • 103 citations

In vitro Evaluation of Immunosuppressive Drugs

1969 • 103 citations

Cellular Immunology and the Pathogenesis of Graft Versus Host Reactions (Part 1 of 3)

1971 • 102 citations

Detection of Agents which Interfere with the Immune Response

1961 • 102 citations

NZB/NZW mice as a model of systemic lupus erythematosus.

1966 • 100 citations

Delayed hypersensitivity.

1966 • 99 citations

Comparative effect of antirheumatic drugs on adjuvant-induced polyarthritis in rats.

1966 • 99 citations

Thymus-Derived Lymphocytes: Humoral and Cellular Reactions Distinguished by Hydrocortisone

1972 • 99 citations

Textbook of Immunopathology.

1969 • 98 citations

CHEESE REACTION AND TYRAMTNE

1971 • 98 citations

In vivo Specific Antigen Recognition by Rosette Forming Cells

1970 • 97 citations

Adjuvant-induced polyarthritis in rats: biologic and histologic background.

1965 • 94 citations

Re-assessment of Boyden's technique for measuring chemotaxis

1972 • 94 citations

Failure of cytotoxic drugs to suppress immune responses of patients with rheumatoid arthritis.

1970 • 93 citations

Antibody Production by Isolated Spleen Cells: A Study of the Cluster and the Plaque Techniques

1968 • 91 citations

Suppression of Experimental Allergic Encephalomyelitis by Stress.

1962 • 88 citations

Leukotactic factors in health and disease.

1971 • 87 citations

NZB/NZW Mice as a Model of Systemic Lupus Erythematosus

1966 • 84 citations

Inhibition of Immediate and Delayed Hypersensitivity in the Rabbit by 6-Mercaptopurine

1964 • 83 citations

Complement in acute inflammation

1969 • 83 citations

ENHANCEMENT OF ANTIBODY SYNTHESIS BY 6-MERCAPTOPURINE

1966 • 83 citations

Therapeutic studies in NZB/W mice. II. Relative efficacy of azathioprine, cyclophosphamide and methylprednisolone

1972 • 83 citations

THE EFFECT OF CYTOTOXIC DRUGS ON GRAFT-VERSUS-HOST DISEASE IN MICE

1971 • 81 citations

PREVENTION OF THE LOCALIZED AND GENERALIZED SHWARTZMAN REACTIONS BY AN ANTICOMPLEMENTARY AGENT, COBRA VENOM FACTOR

1971 • 81 citations

Biochemical demonstration of the activatable esterase of the rabbit netrophil involved in the chemotactic response.

1970 • 76 citations

MICROMETHODS FOR THE STUDY OF PROTEINS AND ANTIBODIES. IV. FACTORS INVOLVED IN THE PREPARATION AND USE OF A STABLE PREPARATION OF FORMALINIZED, TANNIC ACID-TREATED, PROTEIN-SENSITIZED ERYTHROCYTES FOR DETECTION OF ANTIGEN AND ANTIBODY.

1963 • 76 citations

The Use of a Standardized Adjuvant Arthritis Assay to Differentiate Between Anti-inflammatory and Immunosuppressive Agents

1971 • 74 citations

Quantitative studies on tissue transplantation immunity. VII. The normal lymphocyte transfer reaction

1966 • 71 citations

The Inhibitory Effect of Hydrocortisone on Lysis of Homologous Cells by Lymphocytes in Vitro

1962 • 71 citations

Inhibition of the Anaphylactic Mechanism by Sympathomimetic Amines

1971 • 71 citations

IMMUNOSUPPRESSIVE AGENTS

1965 • 71 citations

Therapeutic studies in NZB/W mice. I. Synergy of azathioprine, cyclophosphamide and methylprednisolone in combination

1972 • 68 citations

Disseminated Intravascular Coagulation.

1965 • 68 citations

Production of Graft-Versus-Host Disease in the Rat and its Treatment with Cytotoxic Agents

1966 • 68 citations

Studies on the pathogenesis of the generalized Schwartzman reaction. The role of granulocytes.

1968 • 67 citations

TOLERANCE AND HOMOLOGOUS DISEASE IN IRRADIATED MICE PROTECTED WITH HOMOLOGOUS BONE MARROW

1958 • 67 citations

INCREASED SURVIVAL OF RENAL HOMOGRAFTS IN DOGS AFTER INJECTION OF GRAFT DONOR BLOOD

1964 • 66 citations

Studies on the Mechanism of Action of Methotrexate and Cyclophosphamide on Contact Sensitivity in the Guinea Pig

1964 • 66 citations

Cyclic AMP and immune responses. I. Influence of poly A:U and cAMP on antibody formation in vitro.

1971 • 65 citations

Mode of action of disodium cromoglycate, studies on immediate type hypersensitivity reactions using 'double sensitization' with two antigenically distinct rat reagins.

1970 • 64 citations

The effect of epsilon amino caproic acid and other inhibitors of proteolysis upon the response of human peripheral blood lymphocytes to phytohemagglutinin

1971 • 63 citations

Prevention of secondary immune response with 6-mercaptopurine.

1962 • 63 citations

The relationship of antibody-forming cells to rosette-forming cells.

1971 • 62 citations

Effect of Cyclophosphoramide, 6-Mercaptopurine, Actinomycin D and Vincaleukoblastine on the Acquisition of Delayed Hypersensitivity (DNCB Contact Dermatitis) in the Guinea-Pig11From the Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia 4, Pennsylvania.This study was supported in part by U.S.P.H.S. Training Grant 2 G-62.This investigation was carried out during the tenure of a postdoctoral fellowship, held by Dr. Maibach, from the Division of General Medical …

1961 • 62 citations

Relationship of germinal centers in lymphoid tissue to immunologic memory. V. The effect of prednisolone administered after the peak of the primary response.

1971 • 61 citations

QUANTITATIVE STUDIES ON THE BEHAVIOR OF SENSITIZED LYMPHOCYTES IN VITRO

1965 • 59 citations

Crystal-Induced Arthritis

1969 • 57 citations

SUPPRESSION OF ANTIBODY SYNTHESIS AND PROLONGATION OF HOMOGRAFT SURVIVAL BY CHLORAMPHENICOL

1964 • 55 citations

Clinical Evaluation of a Rosette Inhibition Test in Renal Allotransplantation

1971 • 55 citations

Effect of Cytotoxic Agents on Antibody Production

1960 • 53 citations

Studies on adjuvant‐induced polyarthritis in rats. III. The effect of “immunosuppressive agents” on arthritis and tuberculin hypersensitivity

1964 • 53 citations

Characteristic Features of Immunosuppression by Steroids and Cytotoxic Drugs

1968 • 53 citations

The Inhibition of Lymphocyte Blastogenesis By L-Asparaginase

1970 • 52 citations

Biochemical Demonstration of the Activatable Esterase of the Rabbit Neutrophil Involved in the Chemotactic Response

1970 • 52 citations

Skin Window Studies of the Acute Inflammatory Responses of Neutropenic Patients

1971 • 51 citations

Chemotaxis of polymorphonuclear leukocytes

1968 • 51 citations

Studies on the Suppression of Immune Responses by the Periwinkle Alkaloids Vincristine and Vinblastine*

1964 • 51 citations

THE EFFECT OF 6-MERCAPTOPURINE AND AMINOPTERIN ON EXPERIMENTAL IMMUNE THYROIDITIS IN GUINEA PIGS

1963 • 50 citations

MYCOBACTERIAL ADJUVANT PERIARTHRITIS IN RODENTS AND ITS MODIFICATION BY ANTIINFLAMMATORY AGENTS

1966 • 50 citations

INDUCTION OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN RATS WITHOUT THE AID OF ADJUVANT^*

1965 • 49 citations

The Role of Antigen Dosage in Drug-Induced Immunologic Tolerance

1963 • 49 citations

The in vitro cytotoxicity of human lymphocytes: The effect of metabolic inhibitors

1967 • 49 citations

Effect of Uracil Mustard and Several Antitumor Drugs on the Primary Antibody Response in Rats and Mice

1965 • 49 citations

Estrogen Pharmacology. II. Suppression of Experimental Immune Polyarthritis

1964 • 48 citations

Lymph node permeability factor in the dinitrochlorobenzene skin hypersensitivity reaction in guinea-pigs.

1965 • 48 citations

Comparison of the effects of two cytotoxic drugs and of antilymphocytic serum on immune and non-immune inflammation in experimental animals.

1970 • 48 citations

LEUKOCYTE MOTILITY: II. EFFECT OF ABSENCE OF GLUCOSE IN MEDIUM; EFFECT OF PRESENCE OF DEOXYGLUCOSE, DINITROPHENOL, PUROMYCIN, ACTINOMYCIN D, AND TRYPSIN ON THE RESPONSE TO CHEMOTACTIC SUBSTANCE; EFFECT OF SEGREGATION OF CELLS FROM CHEMOTACTIC SUBSTANCE

1967 • 47 citations

FACTORS AFFECTING THE ANTIBODY RESPONSE

1963 • 46 citations

The Proliferative State of Antigen-Sensitive Precursors of Hemolysin-Producing Cells, Determined by the Use of the Inhibitor, Vinblastine

1966 • 45 citations

Polymorphonuclear leukocyte motility in vitro. I. Effect of pH, temperature, ethyl alcohol, and caffeine, using a modified boyden chamber technic

1969 • 45 citations

Studies of the Mechanism whereby Adjuvant Disease is Suppressed in Rats Pretreated with Mycobacteria

1967 • 44 citations

Adjuvant-Induced Arthritis in Rats I. Temporal Relationship of Physiological, Biochemical, and Hematological Parameters

1971 • 44 citations

Comparative Effects of Some Immunosuppressive and Anti-Inflammatory Drugs on Allergic Encephalomyelitis and Adjuvant Arthritis

1967 • 44 citations

Adjuvant-induced arthritis: effects of certain drugs on incidence, clinical severity, and biochemical changes.

1966 • 44 citations

Studies on phagocytosis

1969 • 43 citations

EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS: THE EFFECT OF 6-MERCAPTOPURINE

1962 • 43 citations

Suppression of Immunity by Phenobarbital

1971 • 43 citations

Differences in the Severity of Adjuvant Arthritis in Four Strains of Rats

1969 • 43 citations

Antiarthritic and Antiinflammatory Effects of Certain Prostaglandins

1972 • 42 citations

The inhibition of adjuvant disease in rats by the interferon‐inducing agent pyran copolymer

1969 • 42 citations

Drug-Induced Immunologic Tolerance: Site of Action of Cyclophosphamide

1970 • 42 citations

Polymorphonuclear leukocyte motility in vitro. II. Stimulatory effect of monosodium urate crystals and urate in solution; partial inhibition by golchicine and indomethacin

1969 • 41 citations

L-Asparaginase: Toxicity to Normal and Leukemic Human Lymphocytes

1967 • 41 citations

Suppressive effects of indomethacin on crystal-induced inflammation in canine joints and on neutrophilic motility in vitro.

1967 • 41 citations

Cyclic AMP and immune responses. II. Phosphodiesterase inhibitors as potentiators of polynucleotide effects on antibody formation.

1971 • 40 citations

Immunosuppression by pyrimidine nucleoside analogs

1966 • 39 citations

Suppression of adjuvant-induced arthritis in the rat by gold sodium thiomalate.

1971 • 39 citations

Pharmacologic Dissociation of Immunologic Release of Histamine and Slow Reacting Substance of Anaphylaxis in Rats

1968 • 38 citations

Cyclic Amp and Immune Responses

1971 • 38 citations

Corticosteroids and the generalized Shwartzman reaction. Mechanisms of sensitization in the rabbit.

1971 • 37 citations

Immunobiology for Surgeons.

1970 • 35 citations

Inhibition by 6-Mercaptopurine of Polyarthritis induced by Freund's Adjuvant

1964 • 35 citations

Differential effects of 6-mercaptopurine and cyclophosphamide on autoimmune phenomena in NZB mice.

1971 • 35 citations

Mechanisms of lymphocyte-induced cell and tissue destruction in vitro.

1970 • 34 citations

Cytochemical and Immunohistologic Investigations on the Source and the Functional Changes of Mononuclear Cells in Skin Window Exudates

1969 • 34 citations

Acute and Chronic Autoimmune Encephalomyelitis: Age, Strain, and Sex Dependency The Importance of the Source of Antigen

1969 • 34 citations

Treatment of Experimental Allergic Encephalomyelitis with Encephalitogenic Basic Proteins

1972 • 34 citations

Immunology for Students of Medicine

1965 • 34 citations

The Effect of Carrageenan on the Establishment of Delayed Hypersensitivity

1971 • 33 citations

Inhibition of immune responses by glutamine antagonism: effect of azotomycin on lymphocyte blastogenesis.

1971 • 33 citations

Is azathioprine a better immunosuppressive than 6-mercaptopurine?

1971 • 31 citations

IMMUNOSUPPRESSION BY L-ASPARAGINASE AND RELATED ENZYMES

1971 • 31 citations

Immunosuppressive Agents

1972 • 31 citations

FURTHER DEVELOPMENTS OF THE ROSETTE INHIBITION TEST FOR THE TESTING OF ANTIHUMAN LYMPHOCYTE SERUM

1971 • 31 citations

Suppression of inflammation and histidine decarboxylase by protein synthesis inhibitors

1968 • 31 citations

Specific immune tolerance to anaphylactic sensitization (egg albumin) induced in the guinea pig by cyclophosphoramide (Cytoxan)

1961 • 31 citations

INHIBITION OF ANAPHYLACTIC SHOCK IN THE RAT BY ANTIHISTAMINES AND ASCORBIC ACID

1966 • 30 citations

Micromethods for the Study of Proteins and Antibodies

1963 • 30 citations

Action of anti-inflammatory agents upon blood and histopathologic changes induced by periarthritis in rats

1966 • 30 citations

A comparison of the effects of melengestrol acetate and hydrocortisone acetate on experimental allergic encephalomyelitis in rats.

1970 • 29 citations

Suppression of Immune Response by ‘Vincristine’ and ‘Vinblastine’

1963 • 29 citations

Anti-lymphocytic antibody and autoimmune disease: a review.

1969 • 29 citations

Immunosuppressive and specific antimitotic effects of ovalicin

1968 • 28 citations

Allergic encephalomyelitis: immunologically specific inhibition of cellular passive transfer by encephalitogenic basic proteins.

1970 • 28 citations

Cyclophosphamide Inhibition of Experimental Allergic Encephalomyelitis in Wistar Rats.

1967 • 28 citations

FUNCTIONING HOMOGRAFTS OF THE LUNG IN DOGS*

1962 • 28 citations

Combined Immunosuppressive Action of Phytohaemagglutinin and Azathioprine (Imuran) on Dogs with Renal Homotransplants

1965 • 28 citations

Mechanisms of Antibody Production

1967 • 28 citations

Studies on phagocytosis. II. The effect of nonsteroidal anti-inflammatory drugs on phagocytosis and on urate crystal-induced canine joint inflammation.

1972 • 28 citations

A comparison of immunosuppressive and anti-inflammatory agents in the rat.

1971 • 28 citations

Inhibition of Adjuvant Arthritis by Statolon.

1967 • 28 citations

Promethazine-HCl as an Immunosuppressant

1972 • 27 citations

Prolonged administration of antithymocyte serum in mice. I. Observations on cellular and humoral immunity.

1971 • 27 citations

PROLONGED ACCEPTANCE OF A CANINE RENAL ALLOGRAFT ACHIEVED WITH PREDNISOLONE

1965 • 27 citations

Cyclic AMP and Immune Responses

1971 • 27 citations

Immunodepression During Urethane and N-Nitrosomethylurea Leukaemogenesis in Mice

1971 • 27 citations

Antibody Production in Guinea Pigs Receiving 6-Mercaptopurine.

1961 • 27 citations

Suppression of the cellular interactions of delayed hypersensitivity by corticosteroid.

1971 • 26 citations

SUPPRESSION OF ADJUVANT‐INDUCED ARTHRITIS IN RATS WITH 2‐BUTOXYCARBONYLMETHYLENE‐4‐OXOTHIAZOLIDINE

1965 • 26 citations

Endocrine Control of Inflammation; Effect of Hormones on Anaphylactic Arthritis

1951 • 26 citations

Prevention of Experimental Allergic Encephalomyelitis with 6-Mercaptopurine.

1960 • 26 citations

Suppression of Experimental Allergic Encephalomyelitis by Cytotoxic Drugs

1963 • 26 citations

Inhibition of Antibody Plaque Formation by Sensitized Lymphoid Cells: Rapid Indicator of Transplantation Immunity

1964 • 26 citations

The Inhibition of Hemagglutinin Formation in Mice by Purine and Pyrimidine Analogues

1962 • 25 citations

Autoimmune Hemolytic Anemia in NZB/Bl Mice Treated with the Corticosteroid Drug Betamethasone

1965 • 25 citations

Effect of Gold Preparations on the Development and Passive Transfer of Experimental Allergic Encephalomyelitis in Rats

1972 • 25 citations

THE IMMUNOSUPPRESSIVE ACTIVITY OF ARA-CYTIDINE

1968 • 25 citations

Phosphonate inhibition of theaccumulation and retention of K+ by rabbit neutrophils in relation to chemotaxis.

1971 • 24 citations

Prostaglandin Inhibition of the Immunologic Release of Slow Reacting Substance of Anaphylaxis in the Rat

1971 • 24 citations

THE WEIGHT-GAIN ASSAY FOR RUNT DISEASE IN MICE *

1960 • 24 citations

THE TREATMENT OF CHRONIC MURINE HOMOLOGOUS DISEASE

1965 • 24 citations

PREVENTION OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS (EAE) BY VITAMIN C DEPRIVATION

1962 • 23 citations

Allergic encephalomyelitis: Inhibition of cellular passive transfer by exogenous and endogenous steroids

1969 • 23 citations

SUPPRESSION OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS BY ANTIMETABOLITES

1965 • 23 citations

IMMUNE CELL COOPERATION, VIRUSES, AND ANTIBODIES TO NUCLEIC ACIDS IN NEW ZEALAND MICE

1971 • 23 citations

PROLONGATION OF CANINE RENAL HOMOGRAFT SURVIVAL BY ANTIMETABOLITES

1963 • 23 citations

Evaluation of potential antirheumatic drugs in vitro using lymphocytes and epithelial cells. The selective action of indoxole, methyl glyoxal and chloroquine

1967 • 23 citations

Effects of several antitumour agents on spleen hemolysin plaque-forming cells

1967 • 22 citations

Lymphocytic Factors in Cellular Hypersensitivity

1971 • 22 citations

CORTISONE ACETATE TREATMENT OF HAEMOLYTIC ANAEMIA IN NZB MICE

1965 • 22 citations

Studies of Cyclophosphamide Suppression of Experimental Allergic Encephalomyelitis in Wistar Rats

1969 • 22 citations

Role of Heredity in Experimental Disseminated Encephalomyelitis in Mice

1954 • 21 citations

Dose-response curves for agents that impair cell reproductive integrity. A fundamental difference between dose-response curves or antimetabolites and those for radiation and alkylating agents.

1969 • 21 citations

Studies on cells producing haemolytic antibodies against sheep red blood cells in short-term experiments in vitro.

1966 • 21 citations

ANTILYMPHOCYTE SERUM IN THE THERAPY AND PREVENTION OF ACUTE SECONDARY DISEASE IN MICE

1969 • 20 citations

Development of Rheumatoid Factor Activity and Cryoglobulins in Primary and Secondary Syphilis

1969 • 20 citations

Effect of Sensitization to BSA on Adjuvant Disease in Normal and Neonatally Thymectomized Rats.

1965 • 20 citations

Antiserum to Lymphocytes and Procarbazine Compared as Immunosuppressants in Mice

1969 • 20 citations

Suppression of the Immune Response by Drugs in Combination

1962 • 20 citations

Immunosuppressive effects of adamantoyl cytarabine—I

1969 • 20 citations

ACTION OF ANTILYMPHOCYTIC SERA ON REACTIONS CAUSED BY IMMUNE-COMPLEX FORMATION

1969 • 20 citations

Chemical Mediators of Immediate Hypersensitivity

1971 • 19 citations

Allergic Encephalomyelitis: Inhibition of Cellular Passive Transfer by X-Radiation

1969 • 19 citations

ANTILYMPHOCYTE SERUM IN THE LATER STAGES OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

1968 • 19 citations

Combined Immunosuppression for Canine Renal Allograft Prolongation

1968 • 18 citations

Cyclophosphamide Treatment of Experimental Allergic Encephalomyelitis in Lewis Rats

1971 • 18 citations

CHEMOTHERAPY OF ESTABLISHED GRAFT-VERSUS-HOST DISEASE IN MICE

1972 • 18 citations

Studies on Immune Suppressive Drugs.

1967 • 17 citations

The Effect of Disodium Cromoglycate and Other Inhibitors on <i>in vitro</i> Anaphylactic Histamine Release from Guinea Pig Basophil Leucocytes

1969 • 17 citations

PROLONGATION OF SKIN XENOGRAFT SURVIVAL BY L-ASPARAGINASE

1971 • 17 citations

Cyclophosphamide treatment of experimental allergic encephalomyelitis in Lewis rats.

1971 • 17 citations

An Investigation into the Use of 6-Mercaptopurine to Induce Immunological Tolerance

1961 • 17 citations

Suppression of Antibody Synthesis by Chloramphenicol Analogs

1969 • 16 citations

Influence of Lysergic Acid Diethylamide on Experimental Allergic Encephalomyelitis.

1962 • 16 citations

Antigen recognition by T-cells and its suppression. Significance and origin of rosette-forming cells.

1971 • 16 citations

Immunopharmacologic effects of cycloleucine.

1972 • 16 citations

Effects of Topical Hydrocortisone and Acetylsalicylic Acid on the Primary Lesion of Adjuvant-Induced Arthritis

1971 • 15 citations

Inhibition of adjuvant arthritis by protein antigens. I. Inhibitory capacities and dose relationships of different proteins.

1969 • 15 citations

The effect of phytohaemagglutinin on the immune response in vivo.

1967 • 15 citations

The Effect of Antihypertensive Agents on the Peripheral Manifestation of Allergic and Other Inflammatory Reactions in the Skin

1969 • 15 citations

THE IMMUNOSUPPRESSIVE EFFECT OF AMANTADINE UPON THE RESPONSE OF LYMPHOCYTES TO SPECIFIC ANTIGENS IN VITRO

1971 • 15 citations

The arthus phenomenon — A mechanism of tissue damage

1967 • 15 citations

Inhibition of Adjuvant-Induced Polyarthritis with Cytarabine

1968 • 14 citations

Corticosteroid modification of guinea-pig anaphylaxis

1969 • 14 citations

Relationship of Germinal Centers in Lymphoid Tissue to Immunologic Memory

1971 • 14 citations

Rifampicin and alanosine inhibition of adjuvant arthritis in rats

1971 • 14 citations

Indomethacin Inhibits the Local Shwartzman Reaction

1970 • 14 citations

Some Remarks on the Past, Present and Future of Allergy

1959 • 14 citations

6‐MERCAPTOPURINE ADMINISTRATION TO NZB MICE

1968 • 14 citations

JERNE PLAQUE ASSAY FOR ANTIBODY-FORMING SPLEEN CELLS

1971 • 14 citations

Phosphonate Inhibition of the Accumulation and Retention of K+ by Rabbit Neutrophils in Relation to Chemotaxis

1971 • 14 citations

Studies on the Inhibition of Antibody Formation in the Guinea-Pig with Cyclophosphamide, Azathiopurine, 5-Fluorouracil and Urethane

1966 • 13 citations

Studies on the mechanism of anaphylaxis: A possible basis for a pharmacologic approach to allergy

1963 • 13 citations

A New Type of Cytotoxic Immunosuppressive Agent: 3-Acetyl-5-(4-fluorobenzylidene)4-hydroxy-2-oxo-2:5-dihydrothiophen

1966 • 13 citations

Alteration of the Homograft Response as a Determinant of Carcinogenicity

2015 • 13 citations

A TEST TO MEASURE THE IMMUNOSUPPRESSIVE POTENCY OF ANTILYMPHOCYTE SERA

1969 • 13 citations

Parallel studies on the effect of anti-lymphocytic antibody on cell mediated and humoral antibody responses in the rat.

1968 • 12 citations

Immunosuppression by compounds which complex with deoxyribonucleic acid

1969 • 12 citations

Hypersensitivity reactions in experimental uremia.

1967 • 11 citations

Studies on the immunosuppressive properties of asparaginase.

1971 • 11 citations

Hydroxyurea: comparison of cytotoxic and antimitotic activities against human lymphocytes in vitro.

1969 • 11 citations

The Effect of 6-Mercaptopurine (6-MP) and Methotrexate (MTX) on Passive Delayed Hypersensitivity Reactions

1968 • 11 citations

Slowed lysosomal enzyme release and its normalization by drugs in adjuvant-induced polyarthritis

1971 • 11 citations

Inhibition of precipitin formation in the guinea-pig with cyclophosphamide

1963 • 10 citations

Inhibition of rat adjuvant arthritis by a new immunosuppressive agent rubidomycin

1968 • 10 citations

Tolerance of Cell Mediated Immune Responses after in vitro Treatment of Competent Cells with Mitomycin c

1969 • 10 citations

Immunosuppressive activity of 3-acetyl-5-(4-fluorobenzylidene)-4-hydroxy-2-oxo-2:5-dihydrothiophen (I.C.I. 47,776).

1968 • 10 citations

Suppression of experimental allergic encephalomyelitis by NSC 82196, a new imidazole carboxamide derivative.

1969 • 10 citations

Antitumor agents on the production of primary and secondary spleen hemolysin plaque-forming cells.

1967 • 10 citations

Cyclophosphamide Inhibition of Experimental Allergic Thyroiditis and Thyroid Antibody Production in Rats

1971 • 9 citations

Enhanced Suppression of Experimental Allergic Encephalomyelitis by Combination Chemotherapy with Duazomycin-A and 6-Mercaptopurine

1969 • 9 citations

Enhanced Suppression of the Secondary Immune Response by Combination of 6-Mercaptopurine ‘Duazomycin A ’

1963 • 9 citations

Studies of histamine release from human leukocytes.

1969 • 9 citations

Lymphocyte Heterogeneity and Function

1973 • 9 citations

Inhibition of Delayed Hypersensitivity in Guinea-pigs after Competition between Synthetic Antigens

1967 • 9 citations

THE EFFECT OF DIMETHYL SULFOXIDE ON THE LOCAL SHWARTZMAN PHENOMENON*

1967 • 9 citations

Prevention of Experimental Allergic Encephalomyelitis by Combination of Epinephrine and a Phenothiazine Derivative, Propiomazine

1969 • 9 citations

Suppressant effect of procarbazine and its comparison with anti-lymphocyte serum in adjuvant-induced polyarthritis in rats.

1970 • 9 citations

L-Asparaginase in Experimental Auto-Immune Disease: Inhibition of Allergic Encephalomyelitis

1970 • 8 citations

Immunosuppressive Effects of Selected Metabolic Inhibitors in Vivo and in Vitro

1968 • 8 citations

Immunopharmacologic activity of 1-aminocyclopentane-1-carboxylic acid

1968 • 8 citations

Production of Generalized Shwartzman Reaction in Rabbits with Nitrogen Mustard-Induced Granulocytopenia.

1967 • 8 citations

MODIFICATION OF THE GRAFT VERSUS HOST REACTION IN F1 MICE TREATED WITH 6-MERCAPTOPURINE1

1966 • 8 citations

Effects of 6-Mercaptopurine on Susceptibility of Guinea Pigs to Experimental Allergic Encephalomyelitis.

1962 • 8 citations

Immunosuppressive effects of bacterial asparaginase on antibody formation and allograft immunity.

1971 • 7 citations

Immunosuppressive Properties of Cyclophosphamide Analogues

1972 • 7 citations

The role of immunologic tolerance in immunologic response.

1966 • 7 citations

Immunologic Tolerance Induced by a Combination of Chloramphenicol and 6-Mercaptopurine

1966 • 7 citations

Cyclosphosphamide inhibition of experimental allergic thyroiditis and thyroid antibody production in rats.

1971 • 7 citations

Aleutian mink and New Zealand mice: models of viral induced connective tissue disease.

1970 • 7 citations

Mechanism of complement action in rosette inhibition and lymphocytotoxicity of antilymphocyte serum.

1972 • 7 citations

Influence of Cytoxan and Poly I{middle dot}C on Early Antinuclear Antibody Responses in New Zealand Black Mice

1972 • 7 citations

CLINICAL INVESTIGATIONS IN MULTIPLE SCLEROSIS: INTRODUCTORY REMARKS

1965 • 6 citations

Mechanisms of Action of Drugs Affecting Immune Responses

1972 • 6 citations

Essentials of Immunology.

1971 • 6 citations

Resistance of the Allergic Contact Dermatitis Sensitization Reaction to Whole Body X-Ray in the Guinea Pig

1966 • 6 citations

Ageing and antibody production in the rat

1965 • 6 citations

The immunosuppressive activity of 9-butylazathioprine, used alone and with azathioprine

1971 • 6 citations

Immunopathologic mechanisms. I. Allergic phenomena mediated by antibody.

1969 • 6 citations

Tissue Transplantation: Scope and Prospect

1966 • 6 citations

Interchangeability of Methotrexate and Cyclophosphamide as Inhibitors of Allergic Contact Dermatitis in the Guinea Pig

1969 • 6 citations

The use of chemotherapeutic agents in the treatment of non-neoplastic diseases

1971 • 5 citations

The effect of 6-mercaptopurine on spontaneous canine asthma

1969 • 5 citations

IMMUNOSUPPRESSIVE EFFECTS OF CYCLOPHOSPHAMIDE AND L-ASPARAGINASE IN THE INBRED RAT RENAL TRANSPLANT MODE

1972 • 5 citations

Inhibition of release of slow-reacting substance by arsenic

1969 • 5 citations

Arthritis and Psoriasis: The Effects of Antipsoriatic Agents in the Adjuvant-Induced Arthritic Rat

1970 • 5 citations

Effect of Drugs on Goldfish Scale Homograft Survival

1963 • 5 citations

Effects of Newer Glucocorticoids on Anaphylactic Shock in the Rat and the Mouse

1968 • 5 citations

THE ROLE OF CYCLIC AMP IN THE IMMUNOCOMPETENT CELL

1971 • 4 citations

Failure of Hypothalamic Lesions to Protect against Experimental Allergic Encephalomyelitis (EAE) in the rat

1969 • 4 citations

Effect of various nucleic acid and protein synthesis inhibitors on anaphylactoid inflammation in rats

1969 • 4 citations

A Micro-system for Screening Anti-leukemic Drugs Utilizing Human Whole Blood

1971 • 4 citations

The influence of chlorambucil on experimental allergic encephalomyelitis

1963 • 4 citations

Influence of antifibrinolytic substances on allergic reactions. Experiments with ε-aminocaproic acid and amino-methyl-cyclohexane-carbonic acid

1968 • 4 citations

Studies of a possible immunosuppressive action of human chorionic gonadotrophin

1972 • 4 citations

On Payment of the Medical Referee by Assurance Companies

1842 • 4 citations

Immune Responses in the Presence of Large Doses of Phenylalanine

1966 • 4 citations

Effect of Endotoxin on the Delayed Hypersensitivity Reaction.

1967 • 3 citations

Suppressive Effect of Anti-Allergic Mediators on Experimental Encephalomyelitis.

1967 • 3 citations

THE IMMUNOSUPPRESSIVE EFFECT OF PROCARBAZINE HYDROCHLORIDE IN CANINE RENAL ALLOGRAFTS

1972 • 3 citations

Failure of chemical antibody suppression to prevent fatal anaphylactic shock.

1963 • 3 citations

Allergy and Tissue Metabolism

1965 • 3 citations

On the mode of action of some immunosuppressant drugs

1968 • 3 citations

Aspects of autoimmunity. 3. Autoimmunity in strains of New Zealand mice.

1966 • 3 citations

Antibody-Mediated Immunodepression in New Zealand Black Mice

1972 • 2 citations

Inhibitory Effect of Large Doses of Histamine on the Passive Arthus Reaction

1967 • 2 citations

A study of the effect of analogs of nucleic acid bases on immunogenesis using Jerne's method

1965 • 1 citations

Immunopathologic mechanisms. II. Allergic phenomena mediated by cells.

1969 • 1 citations

Control of oral anticoagulant treatment.

1971 • 1 citations

Antibody Plaque Formation <i>in vitro </i>in the Presence of Respiration Inhibitors

1972 • 1 citations

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