Mechanisms of Term and Preterm Birth

Marshall’s Physiology of Reproduction

1994 • 1,461 citations

A placental clock controlling the length of human pregnancy

1995 • 897 citations

Endocrine and Paracrine Regulation of Birth at Term and Preterm*

2000 • 842 citations

Oxytocin Receptors and Human Parturition: A Dual Role for Oxytocin in the Initiation of Labor

1982 • 494 citations

The Control of Labor

1999 • 443 citations

Oxytocin Receptors: Triggers for Parturition and Lactation?

1979 • 395 citations

Antenatal Glucocorticoids and Programming of the Developing CNS

2000 • 385 citations

Determinants of Preterm Birth Rates in Canada from 1981 through 1983 and from 1992 through 1994

1998 • 367 citations

Peptide Signaling in Human Placenta and Membranes: Autocrine, Paracrine, and Endocrine Mechanisms*

1996 • 334 citations

Cytokines of the Placenta and Extra-placental Membranes: Roles and Regulation During Human Pregnancy and Parturition

2002 • 329 citations

Contribution of preterm delivery to perinatal mortality.

1976 • 325 citations

Characterization and gestational regulation of corticotropin-releasing hormone messenger RNA in human placenta.

1988 • 267 citations

Synthesis of oxytocin in amnion, chorion, and decidua may influence the timing of human parturition.

1993 • 255 citations

Serum and Glucocorticoid Regulation of Gene Transcription and Expression of the Prostaglandin H Synthase-1 and Prostaglandin H Synthase-2 Isozymes

1993 • 224 citations

Double-blind, randomized, controlled trial of atosiban and ritodrine in the treatment of preterm labor: A multicenter effectiveness and safety study

2000 • 208 citations

Interactions between progesterone receptor isoforms in myometrial cells in human labour

2001 • 200 citations

Changes in the synthesis and metabolism of prostaglandins by human fetal membranes and decidua at labor

1985 • 196 citations

The role of prostaglandins in human parturition

1998 • 190 citations

The Role of Systemic and Intrauterine Infection in Preterm Parturition

1991 • 179 citations

Corticotropin releasing hormone-binding protein (CRH-BP): plasma levels decrease during the third trimester of normal human pregnancy.

1993 • 179 citations

Differential Expression of 11β-Hydroxysteroid Dehydrogenase Types 1 and 2 in Human Placenta and Fetal Membranes¹

1997 • 164 citations

Expression of cyclo-oxygenase types-1 and -2 in human myometrium throughout pregnancy

1999 • 163 citations

Expression of cyclooxygenase types 1 and 2 in human fetal membranes at term

1995 • 161 citations

Maternal Corticotropin-Releasing Hormone Is Increased with Impending Preterm Birth

1998 • 157 citations

Initiation of Parturition

1994 • 152 citations

Prostaglandin endoperoxide-H synthase-1 and -2 messenger ribonucleic acid levels in human amnion with spontaneous labor onset.

1995 • 138 citations

Immunohistochemical localization, messenger ribonucleic acid abundance, and activity of 15-hydroxyprostaglandin dehydrogenase in placenta and fetal membranes during term and preterm labor.

1994 • 137 citations

Prostaglandin Output in Relation to Parturition by Cells Dispersed from Human Intrauterine Tissues*

1983 • 134 citations

Interleukin (IL)-6 and IL-8 Production by Human Amnion: Regulation by Cytokines, Growth Factors, Glucocorticoids, Phorbol Esters, and Bacterial Lipopolysaccharide1

1997 • 117 citations

The Differential Expression of Myometrial Connexin-43, Cyclooxygenase-1 and -2, and Gsα Proteins in the Upper and Lower Segments of the Human Uterus during Pregnancy and Labor1

1999 • 109 citations

Glucocorticoids stimulate the expression of prostaglandin endoperoxide H synthase-2 in amnion cells.

1995 • 108 citations

Prostaglandin endoperoxide-H synthase (PGHS) activity and immunoreactive PGHS-1 and PGHS-2 levels in human amnion throughout gestation, at term, and during labor.

1994 • 105 citations

Cyclooxygenases in reproductive medicine and biology

1999 • 105 citations

Expression of Myometrial Activation and Stimulation Genes in a Mouse Model of Preterm Labor: Myometrial Activation, Stimulation, and Preterm Labor

2000 • 97 citations

Estrogen stimulates oxytocin gene expression in human chorio-decidua.

1995 • 95 citations

Corticotropin releasing hormone-binding protein (CRH-BP): plasma levels decrease during the third trimester of normal human pregnancy

1993 • 93 citations

Steroid Regulation of Prostaglandin Dehydrogenase Activity and Expression in Human Term Placenta and Chorio-Decidua in Relation to Labor1

1999 • 92 citations

Changes in Expression of Contractile FP and Relaxatory EP2 Receptors in Pregnant Rat Myometrium during Late Gestation, at Labor, and Postpartum1

1998 • 90 citations

Differential cyclooxygenase-1 and -2 gene expression in human myometria from preterm and term deliveries.

1994 • 90 citations

Peptide signaling in human placenta and membranes: autocrine, paracrine, and endocrine mechanisms

1996 • 88 citations

Localization of prostaglandin H synthase type 2 protein and mRNA in term human fetal membranes and decidua

1996 • 84 citations

Prostaglandin dehydrogenase and the initiation of labor

1999 • 78 citations

Randomised, double‐blind, placebo controlled pilot study assessing nitroglycerin as a tocolytic

1999 • 77 citations

Fetal and Maternal Oxytocin in Human Parturition

1989 • 77 citations

Glucocorticoids stimulate prostaglandin H synthase type-2 (PGHS-2) in the fibroblast cells in human amnion cultures

1996 • 76 citations

Prostaglandin Production at the Onset of Ovine Parturition Is Regulated by Both Estrogen-Independent and Estrogen-Dependent Pathways¹

2000 • 72 citations

Chorionic prostaglandin catabolism is decreased in the lower uterine segment with term labour

1997 • 72 citations

A role for estriol in human labor, term and preterm

1999 • 71 citations

Prostaglandin F2 Potentiates Cortisol Production by Stimulating 11 -Hydroxysteroid Dehydrogenase 1: A Novel Feedback Loop That May Contribute to Human Labor

2001 • 68 citations

Paradoxical stimulation of both lipocortin and prostaglandin production in human amnion cells by dexamethasone

1988 • 66 citations

Can Excess Glucocorticoid, in Utero, Predispose to Cardiovascular and Metabolic Disease in Middle Age?

1999 • 61 citations

The molecular basis of labour and tocolysis

1998 • 60 citations

Vaginal fetal fibronectin measurements from 8 to 22 weeks' gestation and subsequent spontaneous preterm birth

2000 • 58 citations

Oxytocin and its Receptor in the Process of Parturition

2001 • 55 citations

The Endocrinology of Human Parturition

1997 • 54 citations

Key enzymes of prostaglandin biosynthesis and metabolism. Coordinate regulation of expression by cytokines in gestational tissues: a review

1999 • 53 citations

Regional variations in contractile responses to prostaglandins and prostanoid receptor messenger ribonucleic acid in pregnant baboon uterus

1998 • 53 citations

Differential Changes in 15-Hydroxyprostaglandin Dehydrogenase and Prostaglandin H Synthase (Types I and II) in Human Pregnant Myometrium

2002 • 51 citations

Changes in activity of cytosolic phospholipase A2 in human amnion at parturition

1997 • 49 citations

Differential cyclooxygenase-1 and -2 gene expression in human myometria from preterm and term deliveries

1994 • 45 citations

Effects of Gestational Age and Labor on Expression of Prostanoid Receptor Genes in Baboon Uterus1

2001 • 42 citations

Fetal-to-Maternal Progression of Prostaglandin H2 Synthase-2 Expression in Ovine Intrauterine Tissues During the Course of Labor1

2000 • 41 citations

Corticotropin-Releasing Hormone Stimulates P450 17α-Hydroxylase/17,20-Lyase in Human Fetal Adrenal Cells via Protein Kinase C*

1999 • 41 citations

Expression and Localization of the Contractile Prostaglandin F Receptor in Pregnant Rat Myometrium in Late Gestation, Labor, and Postpartum1

2001 • 36 citations

Expression of prostaglandin H synthase isoforms in human myometrium at parturition

1999 • 34 citations

Regulation of Placental Corticotropin‐Releasing Hormone by Steroids

1995 • 32 citations

Chapter 14. Prostanoid receptors and signal transduction

1996 • 31 citations

Altered Fetal Pituitary-Adrenal Function in the Ovine Fetus Treated with RU486 and Meloxicam, an Inhibitor of Prostaglandin Synthase-II1

2000 • 31 citations

Cortisol/Progesterone Antagonism in Regulation of 15-Hydroxysteroid Dehydrogenase Activity and mRNA Levels in Human Chorion and Placental Trophoblast Cells at Term

2002 • 30 citations

Immunohistochemical localization of phospholipase A2 isoforms in human myometrium during pregnancy and parturition

1997 • 29 citations

Dexamethasone stimulates arachidonic acid conversion to prostaglandin E2 in human amnion cells.

1989 • 28 citations

Cyclooxygenases in Reproductive Medicine and Biology

1999 • 28 citations

Temporal Expression of Prostaglandin H Synthase Type 2 (PGHS-2) and P450C17in Ovine Placentomes with the Natural Onset of Labour

2000 • 28 citations

Primary Culture of Cells from Human Chorion Laeve: Steroid Metabolism and Properties of Cells Grown in Defined Media Supplemented with 0.1% or 10% Fetal Calf Serum *

1986 • 20 citations

Use of Fetal Fibronectin in Women at Risk For Preterm Delivery

2000 • 16 citations

Expression of Prostaglandin Endoperoxide H Synthase 1 and 2 in Human Placenta at Term

1997 • 16 citations

The Canadian Consensus on the Use of Tocolytics for Preterm Labour

1995 • 12 citations

Characterization of Cyclin D2 Expression in Human Endometrium

2002 • 10 citations

The effects on offspring of premature parturition

2001 • 9 citations