High plasticity of multispecific DNA methyltransferases in the region carrying DNA target recognizing enzyme modules.

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector

1986 • 1,053 citations

Predictive motifs derived from cytosine methyltransferases

1989 • 505 citations

Escherichia coli K-12 restricts DNA containing 5-methylcytosine.

1986 • 325 citations

Sequence of the D-aspartyl/L-isoaspartyl protein methyltransferase from human erythrocytes

1989 • 254 citations

Direct identification of the active-site nucleophile in a DNA (cytosine-5)-methyltransferase

1991 • 246 citations

Cytosine-specific type II DNA methyltransferases

1989 • 230 citations

DNA methylation. The effect of minor bases on DNA-protein interactions

1990 • 181 citations

Sequence motifs characteristic of DNA[cytosine-N4]methyltransferases: similarity to adenine and cytosine-C5 DNA-methylases

1989 • 152 citations

The sequence specificity domain of cytosine-C5 methylases

1991 • 108 citations

Construction and use of chimeric SPR/phi 3T DNA methyltransferases in the definition of sequence recognizing enzyme regions.

1987 • 96 citations

Cytosine-specific DNA modification interferes with plasmid establishment in Escherichia coli K12: Involvement of rglB

1986 • 82 citations

Organization of multispecific DNA methyltransferases encoded by temperate Bacillus subtilis phages.

1987 • 74 citations

Chimeric multispecific DNA methyltransferases with novel combinations of target recognition

1988 • 72 citations

Restriction and modification in Bacillus subtilis: nucleotide sequence, functional organization and product of the DNA methyltransferase gene of bacteriophage SPR

1984 • 67 citations

Agmenellum quadruplicatum M.AquI, a novel modification methylase

1990 • 51 citations

The amino acid sequence of the CCGG recognizing DNA methyltransferase M.BsuFI: implications for the analysis of sequence recognition by cytosine DNA methyltransferases.

1990 • 35 citations

'Pseudo' domains in phage-encoded DNA methyltransferases

1991 • 31 citations

Characterization of the mcrBC region of Escherichia coli K-12 wild-type and mutant strains

1992 • 27 citations

M · H2I, a multispecific 5C-DNA methyltransferase encoded by Bacillus amyloliquefaciens phage H2

1991 • 22 citations

Complementation by detached parts of GGCC-specific DNA methyltransferases

1991 • 17 citations