Deletion of the Extracellular Membrane-Distal Cytokine Receptor Homology Module of Mpl Results in Constitutive Cell Growth and Loss of Thrombopoietin Binding

Structural design and molecular evolution of a cytokine receptor superfamily.

1990 • 2,104 citations

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand

1994 • 1,328 citations

Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

1994 • 1,138 citations

Stimulation of B-cell progenitors by cloned murine interleukin-7

1988 • 826 citations

A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors

1990 • 404 citations

Dissecting the thrombopoietin receptor: Functional elements of the Mpl cytoplasmic domain

1997 • 158 citations

Human Platelets Display High-Affinity Receptors for Thrombopoietin

1997 • 137 citations

Characterization of the murine Mpl proto-oncogene, a member of the hematopoietic cytokine receptor family: molecular cloning, chromosomal location and evidence for a function in cell growth.

1993 • 134 citations

Activating Mutations in Cytokine Receptors: Implications for Receptor Function and Role in Disease

1997 • 58 citations

Structure and transcription of the genomic locus encoding murine c-Mpl, a receptor for thrombopoietin.

1995 • 39 citations

Structure of mouse interleukin 3 (IL-3) binding protein (AIC2A). Amino acid residues critical for IL-3 binding.

1992 • 37 citations

Extracellular truncations of h beta c, the common signaling subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-5, lead to ligand-independent activation

1996 • 29 citations