Pharmacokinetic Considerations in the Use of Genes as Pharmaceuticals

Direct Gene Transfer into Mouse Muscle in Vivo

1990 • 3,985 citations

Receptor-mediated in vitro gene transformation by a soluble DNA carrier system.

1987 • 841 citations

Receptor-mediated gene delivery and expression in vivo.

1988 • 642 citations

Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats

1991 • 349 citations

Targeting Genes: Delivery and Persistent Expression of a Foreign Gene Driven by Mammalian Regulatory Elements in Vivo

1989 • 292 citations

Principles of Drug Action

1990 • 243 citations

Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro

1988 • 221 citations

In VivoGene Transfer into Rabbit Thyroid Follicular Cells by Direct DNA Injection

1994 • 141 citations

Overexpression of Human Methylmalonyl CoA Mutase in Mice afterIn VivoGene Transfer with Asialoglycoprotein/Polylysine/DNA Complexes

1994 • 104 citations

A novel mechanism for achieving transgene persistence in vivo after somatic gene transfer into hepatocytes.

1992 • 92 citations

Expression of Recombinant Human Methylmalonyl-CoA Mutase: In Primary mut Fibroblasts and Saccharomyces cerevisiae

1993 • 34 citations

Bradykinin and Kininogens in Bovine Milk

1989 • 33 citations

Perspectives on methylmalonic acidemia resulting from molecular cloning of methylmalonyl CoA mutase

1990 • 32 citations

Clinical application of somatic gene therapy in inborn errors of metabolism

1990 • 26 citations

Principles of drug action

2011 • 25 citations

Somatic Gene Therapy in Gastroenterology

1992 • 20 citations

Clinical Considerations in the Design of Protocols for Somatic Gene Therapy

1991 • 19 citations

Propionate metabolism in cultured human cells after overexpression of recombinant methylmalonyl CoA mutase: Implications for somatic gene therapy

1992 • 14 citations

Organ transplantation for genetic disease in children

1992 • 5 citations