Biosynthesis of active oestrogens in the breast

Etiology of Human Breast Cancer: A Review2

1973 • 781 citations

In Situ Estrogen Production via the Estrone Sulfatase Pathway in Breast Tumors: Relative Importance versus the Aromatase Pathway*

1984 • 403 citations

Aromatase, 17β-hydroxysteroid dehydrogenase and intratissular sex hormone concentrations in cancerous and normal glandular breast tissue in postmenopausal women

1986 • 249 citations

THE RELATIONSHIP BETWEEN 17β‐HYDROXYSTEROID DEHYDROGENASE ACTIVITY AND OESTROGEN CONCENTRATIONS IN HUMAN BREAST TUMOURS AND IN NORMAL BREAST TISSUE

1983 • 188 citations

Estrogen induction of growth factors specific for hormone-responsive mammary, pituitary, and kidney tumor cells.

1978 • 181 citations

Serum concentrations of total and non‐protein‐bound oestradiol in patients with breast cancer and in normal controls

1982 • 179 citations

STUDIES WITH TRITIUM-LABELLED HEXŒSTROL IN ADVANCED BREAST CANCER

1961 • 167 citations

SEX HORMONE LEVELS IN SERUM IN RELATION TO THE DEVELOPMENT OF BREAST CANCER

1987 • 164 citations

Aromatization of androgens by human breast cancer

1979 • 144 citations

Inadequate corpus luteum function: a pathophysiological interpretation of human breast cancer epidemiology.

1974 • 142 citations

Biological Significance of Aromatase Activity in Human Breast Tumors*

1983 • 134 citations

ŒSTRADIOL SYNTHESIS BY A HUMAN BREAST CARCINOMA

1974 • 119 citations

Plasma levels of estrone, estrone sulfate, and estradiol and the percentage of unbound estradiol in postmenopausal women with and without breast disease.

1983 • 117 citations

Estrogen synthesis and estradiol binding by human mammary tumors.

1978 • 78 citations

The Interaction of C-17 Esters of Estradiol with the Estrogen Receptor*

1984 • 74 citations

Estradiol Fatty Acid Esters Occur Naturally in Human Blood

1983 • 72 citations

Non-protein bound oestradiol, sex hormone binding globulin, breast cancer and breast cancer risk

1985 • 68 citations

Plasma concentration gradient of steroid hormones across human mammary tumours in vivo

1981 • 67 citations

17β-Hydroxysteroid Dehydrogenase Activity in Human Breast Epithelial Cell and Fibroblast Cultures

1984 • 64 citations

Steroid modulation of aromatase activity in human cultured breast carcinoma cells

1988 • 63 citations

Extraglandular oestrogen formation and serum binding of oestradiol: relationship to cancer.

1981 • 63 citations

Aromatization of steroids in peripheral tissues

1983 • 59 citations

A reassessment of the role of breast tumor aromatization.

1982 • 56 citations

Formation of estradiol-17β fatty acyl 17-esters in mammary tumors

1982 • 42 citations

Synthesis of estradiol fatty acid esters by human breast tumors: Fatty acid composition and comparison to estrogen and progesterone receptor content

1985 • 37 citations

The role of tissue steroids in regulating aromatase and oestradiol 17β-hydroxysteroid dehydrogenase activities in breast and endometrial cancer

1986 • 35 citations

Aromatization of testosterone and oestrogen receptor levels in human breast cancer

1981 • 33 citations

Estrogen synthesis and estradiol binding by human mammary tumors

1979 • 29 citations

Metabolism and Tissue Uptake of Estrogen in Women with Advanced Carcinoma of the Breast¹

1969 • 28 citations

Sex Hormone Binding Globulin as a Reliable Indicator of Hormone Dependence in Human Breast Cancer

1979 • 27 citations

Biogenesis of steroid hormones by human mammary gland in vivo and in vitro

1976 • 26 citations

Observations on the Role of Circulating Lymphocytes in Thyroid Auto-immunity

1969 • 23 citations

The Effect of Glucocorticoids on theIn VivoConversion of Androstenedione to Oestrone

1986 • 20 citations

Comparison of levels of cytosol estrogen receptors with “arterial” and “venous” concentrations of gonadic steroids in mammary tumors

1981 • 9 citations

[Evaluation of 17-beta-hydroxysteroid dehydrogenase activity as a marker of the hormone dependence of breast cancers].

1985 • 4 citations