Role of pertussis toxin-sensitive guanosine triphosphate-binding proteins in the response of erythroblasts to erythropoietin

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Isolation and characterization of genomic and cDNA clones of human erythropoietin

1985 • 1,101 citations

Human IL-3 (multi-CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3

1986 • 823 citations

Measurement of cytosolic free Ca2+ in individual small cells using fluorescence microscopy with dual excitation wavelengths

1985 • 660 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of the toxin-specific substrate in the Ca2+-mobilizing receptor-mediated biosignaling system.

1985 • 509 citations

ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizing biosignaling.

1984 • 389 citations

Human Recombinant Granulocyte-Macrophage Colony-Stimulating Factor: A Multilineage Hematopoietin

1985 • 374 citations

Signal transduction by guanine nucleotide binding proteins

1987 • 362 citations

Molecular basis for two forms of the G protein that stimulates adenylate cyclase.

1986 • 319 citations

Highly Cooperative Opening of Calcium Channels by Inositol 1,4,5-Trisphosphate

1988 • 307 citations

Techniques used in the identification and analysis of function of pertussis toxin-sensitive guanine nucleotide binding proteins

1988 • 275 citations

G protein multiplicity in eukaryotic signal transduction systems

1988 • 267 citations

Direct G protein gating of ion channels

1988 • 258 citations

Inhibition by islet-activating protein of a chemotactic peptide-induced early breakdown of inositol phospholipids and Ca2+ mobilization in guinea pig neutrophils.

1985 • 250 citations

Splice Variants of the α Subunit of the G Protein G _s Activate Both Adenylyl Cyclase and Calcium Channels

1989 • 225 citations

Molecular analysis of signal transduction by growth factors

1988 • 224 citations

[45] ADP-ribosylation of membrane components by pertussis and cholera toxin

1985 • 209 citations

Cholera toxin inhibits the T-cell antigen receptor-mediated increases in inositol trisphosphate and cytoplasmic free calcium.

1986 • 202 citations

A new GTP‐binding protein in brain tissues serving as the specific substrate of islet‐activating protein, pertussis toxin

1987 • 189 citations

The mechanism of action of erythropoietin

1986 • 185 citations

The regulation of glucose transport by cAMP stimulators via three different mechanisms in rat and human adipocytes.

1983 • 170 citations

Activation of a G protein promotes agonist responses to calcium channel ligands

1987 • 160 citations

Angiotensin II-induced stimulation of voltage-dependent Ca2+ currents in an adrenal cortical cell line.

1988 • 134 citations

Amiloride inhibits murine erythroleukemia cell differentiation: evidence for a Ca2+ requirement for commitment.

1980 • 101 citations

Erythropoietin stimulates a rise in intracellular free calcium concentration in single early human erythroid precursors.

1988 • 91 citations

Erythropoietin stimulates a rise in intracellular-free calcium concentration in single BFU-E derived erythroblasts at specific stages of differentiation

1989 • 78 citations

Erythropoietin stimulates 45Ca2+ uptake in Friend virus-infected erythroid cells.

1984 • 76 citations

Involvement of guanine nucleotide binding proteins in neutrophil activation and priming by GM-CSF

1989 • 56 citations

Three-dimensional intracellular calcium gradients in single human burst-forming units-erythroid-derived erythroblasts induced by erythropoietin.

1990 • 48 citations

Inhibition of interleukin 3 and colony-stimulating factor 1-stimulated marrow cell proliferation by pertussis toxin

1988 • 42 citations

Stimulation of the adenylate cyclase activity of rabbit bone marrow immature erythroblasts by erythropoietin and haemin

1986 • 37 citations

The effect of recombinant erythropoietin on intracellular free calcium in erythropoietin-responsive cells

1989 • 35 citations

Erythropoietin induces rapid increases in intracellular free calcium in human bone marrow cells.

1988 • 34 citations

The effects of pertussis toxin and cholera toxin on mitogen-induced interleukin-2 production: Evidence for G protein involvement in signal transduction

1988 • 26 citations

Mode of action of erythropoietin (Epo) in an Epo-dependent murine cell line. I. Involvement of adenosine 3',5'-cyclic monophosphate not as a second messenger but as a regulator of cell growth.

1989 • 26 citations

The role of cAMP and calcium in the stimulation of proliferation of immature erythroblasts by erythropoietin

1987 • 23 citations

Mechanism of erythropoietin action on the erythroid progenitor cells induced from murine erythroleukemia cells (TSA8)

1989 • 22 citations

Expression of G proteins in rat cardiac myocytes: effect of KCl depolarization

1990 • 22 citations