Selective and Non-Selective Seizure Related Brain Damage Produced by Kainic Acid

Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy

1985 • 1,730 citations

Release of endogenous Zn2+ from brain tissue during activity

1984 • 1,125 citations

Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats

1985 • 1,101 citations

Control of the repetitive discharge of rat CA 1 pyramidal neurones in vitro.

1984 • 748 citations

Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: A histological study

1980 • 700 citations

Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy

1981 • 654 citations

The neurotoxicity of excitatory amino acids is produced by passive chloride influx

1985 • 634 citations

“Epileptic” brain damage in rats induced by sustained electrical stimulation of the perforant path. I. Acute electrophysiological and light microscopic studies

1983 • 554 citations

Kainic acid induced seizures: Neurochemical and histopathological changes

1983 • 526 citations

The distribution of [3H]kainic acid binding sites in rat CNS as determined by autoradiography

1982 • 481 citations

Immunohistochemical mapping of vitamin D-dependent calcium-binding protein in brain

1981 • 405 citations

Electron microscopical localization of the zinc in hippocampal mossy fibre synapses by a modified sulfide silver procedure

1967 • 393 citations

Maturation of kainic acid seizure-brain damage syndrome in the rat. II. Histopathological sequelae

1984 • 355 citations

Kainic acid neurotoxicity toward hippocampal formation: Dependence on specific excitatory pathways

1980 • 286 citations

Autoradiographic localization of high-affinity [3H]kainic acid binding sites in the rat forebrain

1983 • 227 citations

Maturation of kainic acid seizure-brain damage syndrome in the rat. i. clinical, electrographic and metabolic observations

1984 • 207 citations

Electrophysiological mechanisms of kainic acid-induced epileptiform activity in the rat hippocampal slice

1984 • 199 citations

Hippocampal seizures and failure of inhibition

1979 • 181 citations

Comparative toxicity of kainic acid and other acidic amino acids toward rat hippocampal neurons

1981 • 160 citations

Spontaneous and evoked release of endogenous Zn2+ in the hippocampal mossy fiber zone of the rat in situ

1985 • 154 citations

On the relationship between kainic acid-induced epileptiform activity and hippocampal neuronal damage

1981 • 152 citations

Kainic acid produces depolarization of CA3 pyramidal cells in the in vitro hippocampal slice

1981 • 148 citations

Do kainate-lesioned hippocampi become epileptogenic?

1985 • 125 citations

Changes in extracellular Ca²⁺ and K⁺ activity accompanying hippocampal discharges

1980 • 125 citations

Kainate-like neurotoxicity of folates

1981 • 108 citations

Blood flow compensates oxygen demand in the vulnerable ca3 region of the hippocampus during kainate-induced seizures

1984 • 86 citations

Hippocampal Pathology in Temporal Lobe Epilepsy. A Golgi Survey

1973 • 70 citations

Autoradiographic visualization of [3H]kainic acid receptor subtypes in the rat hippocampus

1983 • 68 citations

Evidence from lesion studies for epileptogenic and non-epileptogenic neurotoxic interactions between kainic acid and excitatory innervation

1981 • 54 citations

Divalent transition-metal ions (Cu2+ and Zn2+) in the brains of epileptogenic and normal mice

1983 • 53 citations

3H-kainic acid binding: Relevance for evaluating the neurotoxicity of kainic acid

1979 • 51 citations

A multidisciplinary study of folic acid neurotoxicity: Interactions with kainate binding sites and relevance to the aetiology of epilepsy

1984 • 18 citations