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[12] One-step gene disruption in yeast

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1987 • 332 citations

Naturally occurring escape mutants of hepatitis B virus with various mutations in the S gene in carriers seropositive for antibody to hepatitis B surface antigen

1994 • 304 citations

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1993 • 224 citations

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1992 • 211 citations

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1992 • 187 citations

Genetic alterations in the gene encoding the major HBsAg: DNA and immunological analysis of recurrent HBsAg derived from monoclonal antibody—treated liver transplant patients

1992 • 183 citations

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1984 • 158 citations

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1991 • 146 citations

A novel hepatitis B virus variant in the sera of immunized children

1994 • 130 citations

Mutational analysis of the cysteine residues in the hepatitis B virus small envelope protein

1993 • 128 citations

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1991 • 121 citations

Gly145 to Arg substitution in HBs antigen of immune escape mutant of hepatitis B virus

1992 • 115 citations

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1994 • 90 citations

Mutants of the hepatitis b virus surface antigen that define some antigenically essential residues in the immunodominant a region

1989 • 60 citations

Hepatitis B virus (HBV)-specific cytotoxic T-cell (CTL) response in humans: characterization of HLA class II-restricted CTLs that recognize endogenously synthesized HBV envelope antigens

1992 • 52 citations

Glycine-to-arginine substitution at codon 145 of HBsAg in two infants Born to hepatitis B e antigen-positive carrier

1995 • 47 citations

Mutations of some critical amino acid residues in the hepatitis B virus surface antigen

1995 • 43 citations

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1996 • 40 citations

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1984 • 32 citations

A new immune escape mutant of hepatitis B virus with an Asp to Ala substitution in aa144 of the envelope major protein

1995 • 29 citations

Variant of hepatitis B virus isolated in zimbabwe

1994 • 28 citations

Site‐directed mutagenesis of cysteine residues of hepatitis B surface antigen Analysis of two single mutants and the double mutant

1994 • 25 citations

A Novel Antibody Escape Variant (Ala 144) of Hepatitis B Virus in an Identical Twin Before Selection in the Mother

1994 • 24 citations

A family cluster of an immune escape variant of hepatitis B virus infecting a mother and her two fully immunized children

1995 • 17 citations

Hepatitis B Virus Variants with Altered a Determinants Causing Infections in Immunized Children

1994 • 10 citations